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B6.Cg-Nr1i3tm1(NR1I3)Arte Cyp3a13tm1Nki Cyp3atm1109(CYP3A4,CYP3A7)Arte Cyp1a2tm2024.1(CYP1A2)Arte Cyp1a1tm2025.1(CYP1A1)Arte Cyp2dtm1836.1(CYP2D6_i2)Arte Nr1i2tm1(NR1I2)Arte Cyp2ctm1897.1(Alb-CYP2C9)Arte/Tac Strain Detail
Summary
  • Strain Name
    B6.Cg-Nr1i3tm1(NR1I3)Arte Cyp3a13tm1Nki Cyp3atm1109(CYP3A4,CYP3A7)Arte Cyp1a2tm2024.1(CYP1A2)Arte Cyp1a1tm2025.1(CYP1A1)Arte Cyp2dtm1836.1(CYP2D6_i2)Arte Nr1i2tm1(NR1I2)Arte Cyp2ctm1897.1(Alb-CYP2C9)Arte/Tac
  • Attributes
    mutant strain, targeted mutation
  • MGI ID
    MGI:6405110
  • Synonyms
    8HUM, B6.Cg-Nr1i3tm1(NR1I3)Arte Cyp3a13tm1Ahs Cyp3atm1109(CYP3A4,CYP3A7)Arte Cyp1a2tm2024.1(CYP1A2)Arte Cyp1a1tm2025.1(CYP1A1)Arte Cyp2dtm1836.1(CYP2D6_i2)Arte Nr1i2tm1(NR1I2)Arte Cyp2ctm1897.1(Alb-CYP2C9)Arte/Tac
Associated
Mutations,
Markers,
and QTL
7 associated mutations
References
  • Earliest
    J:286122 Henderson CJ, et al., An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials. Drug Metab Dispos. 2019 Jun;47(6):601-615
  • All
    1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory