B6.Cg-Tg(K18-ACE2)2Prlmn/J Strain Detail MGI Mouse MGI:6389236

B6.Cg-Tg(K18-ACE2)2Prlmn/J Strain Detail

Summary

1 associated mutation

Mutation Carried	Marker
Tg(K18-ACE2)2Prlmn	Tg(K18-ACE2)2Prlmn

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Human Diseases

	model 1
COVID-19	√

Key

√

disease model

expected model not found

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
JAX:034860	JAX	B6.Cg-Tg(K18-ACE2)2Prlmn/J	exact match to ID

Earliest

J:283648 McCray PB Jr, et al., Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. J Virol. 2007 Jan;81(2):813-21
All

127

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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