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B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax Strain Detail
Summary
  • Strain Name
    B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax
  • Attributes
    congenic, mutant strain, transgenic
  • MGI ID
    MGI:3611279
  • Synonyms
    B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/J
  • Other IDs
    JAX:005864, MMRRC:034832
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
Alzheimer's disease
Key disease model expected model not found
Find Mice (IMSR)
1 associated strain record at IMSR
IMSR Repository IMSR Strain Why Matched
MMRRC:034832 MMRRC B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax exact match to ID
References
  • Earliest
    J:87691 Jankowsky JL, et al., Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Hum Mol Genet. 2004 Jan 15;13(2):159-70
  • All

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory