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Sequence Detail
Q9R0S2 A2AUV7 Q9Z0J9 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2019-05-08
from provider
RecName: Full=Matrix metalloproteinase-24; Short=MMP-24; EC=3.4.24.-;AltName: Full=Matrix metalloproteinase-21; Short=MMP-21;AltName: Full=Membrane-type matrix metalloproteinase 5; Short=MT-MMP 5; Short=MTMMP5;AltNa
Polypeptide 618 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Mmp24 matrix metallopeptidase 24 28 4 9 5
Sequence references in MGI J:50709 Pei D, Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP. J Biol Chem. 1999 Mar 26;274(13):8925-32
J:73165 Hayashita-Kinoh H, et al., Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth. Cell Growth Differ. 2001 Nov;12(11):573-80
J:153230 Folgueras AR, et al., Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16451-6
J:212810 Wang P, et al., Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV. J Biol Chem. 2004 May 7;279(19):20461-70
J:213556 Porlan E, et al., MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin. Nat Cell Biol. 2014 Jul;16(7):629-38

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory