Sequence Detail

ID/Version

Q9QXS1 E9QN87 Q9CS65 Q9QXQ9 Q9QXQ8 Q9QXR0 Q9QXR8 Q9QXR4 Q6S384 Q9QXR7 Q9QXR9 Q9QUT2 Q9QXS2 Q9QXR2 Q9QXS0 Q6S394 Q9QXR1 Q9QXR5 Q6S389 Q9QXS3 Q9QXR3 Q9QXR6 (UniProt | EBI)

Last sequence update: 2014-04-16
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Plectin; Short=PCN; Short=PLTN;AltName: Full=Plectin-1;AltName: Full=Plectin-6;

Provider

SWISS-PROT

Sequence

Polypeptide 4691 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plec	plectin	112	100	4	36

Sequence references in MGI

J:58810 Fuchs P, et al., Unusual 5' transcript complexity of plectin isoforms: novel tissue-specific exons modulate actin binding activity. Hum Mol Genet. 1999 Dec;8(13):2461-72
J:78852 Lunter PC, et al., Direct binding of plectin to Fer kinase and negative regulation of its catalytic activity. Biochem Biophys Res Commun. 2002 Aug 30;296(4):904-10
J:86756 Zhang T, et al., Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation. Genome Res. 2004 Jan;14(1):79-89
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104496 Wilhelmsen K, et al., Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin. J Cell Biol. 2005 Dec 5;171(5):799-810
J:115898 Sevcik J, et al., Actin-binding domain of mouse plectin. Crystal structure and binding to vimentin. Eur J Biochem. 2004 May;271(10):1873-84
J:140957 Nery FC, et al., TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton. J Cell Sci. 2008 Oct 15;121(Pt 20):3476-86
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:156784 Steiner-Champliaud MF, et al., BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin. Exp Cell Res. 2010 Feb 1;316(3):297-313
J:175548 Maddala R, et al., Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers. Dev Biol. 2011 Sep 1;357(1):179-90
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:322687 Bouameur JE, et al., Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure. J Invest Dermatol. 2014 Nov;134(11):2776-2783