Sequence Detail

ID/Version

Q9ET39 C6ESQ1 Q9ET40 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=SLAM family member 6;AltName: Full=Lymphocyte antigen 108;AltName: CD_antigen=CD352;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 351 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slamf6	SLAM family member 6	12	96	3	12

Sequence references in MGI

J:60849 Peck SR, et al., Ly108: a new member of the mouse CD2 family of cell surface proteins. Immunogenetics. 2000 Nov;52(1-2):63-72
J:127620 Griewank K, et al., Homotypic interactions mediated by slamf1 and slamf6 receptors control NKT cell lineage development. Immunity. 2007 Nov;27(5):751-62
J:151768 Dong Z, et al., Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells. Nat Immunol. 2009 Sep;10(9):973-80
J:157915 Cannons JL, et al., Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity. 2010 Feb 26;32(2):253-65
J:177322 Keszei M, et al., A novel isoform of the Ly108 gene ameliorates murine lupus. J Exp Med. 2011 Apr 11;208(4):811-22
J:187429 Kageyama R, et al., The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. Immunity. 2012 Jun 29;36(6):986-1002
J:244548 Wong EB, et al., B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance. J Immunol. 2015 May 01;194(9):4130-43
J:244675 Wang N, et al., Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors. Front Immunol. 2015;6:158
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89