Sequence Detail

ID/Version

Q8CIV7 Q9D949 Q505Q7 Q8K0D6 Q6F661 Q8CIV6 (UniProt | EBI)

Last sequence update: 2011-06-28
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Transcription factor Ovo-like 2 {ECO:0000305}; Short=mOvo2;AltName: Full=Zinc finger OVO2;AltName: Full=Zinc finger protein 339;AltName: Full=Zinc finger protein mOVO;

Provider

SWISS-PROT

Sequence

Polypeptide 274 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ovol2	ovo like zinc finger 2	48	105	3	31

Sequence references in MGI

J:45546 Masu Y, et al., Expression of murine novel zinc finger proteins highly homologous to Drosophila ovo gene product in testis. FEBS Lett. 1998 Jan 16;421(3):224-8
J:78915 Li B, et al., Ovol2, a Mammalian Homolog of Drosophila ovo: Gene Structure, Chromosomal Mapping, and Aberrant Expression in Blind-Sterile Mice. Genomics. 2002 Sep;80(3):319
J:91895 Unezaki S, et al., Characterization of the isoforms of MOVO zinc finger protein, a mouse homologue of Drosophila Ovo, as transcription factors. Gene. 2004 Jul 7;336(1):47-58
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106405 Mackay DR, et al., The mouse Ovol2 gene is required for cranial neural tube development. Dev Biol. 2006 Mar 1;291(1):38-52
J:211311 Watanabe K, et al., Mammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressor. Dev Cell. 2014 Apr 14;29(1):59-74
J:213415 Lee B, et al., Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells. Dev Cell. 2014 Apr 14;29(1):47-58
J:284691 Hayashi M, et al., Conserved role of Ovo in germline development in mouse and Drosophila. Sci Rep. 2017 Jan 6;7:40056
J:330954 Zhang Z, et al., Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis. Cell Metab. 2022 Nov 1;34(11):1860-1874.e4