Sequence Detail

ID/Version

Q8BYK4 Q9D1Y4 Q91WA5 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Retinol dehydrogenase 12; EC=1.1.1.300 {ECO:0000250|UniProtKB:Q96NR8};

Provider

SWISS-PROT

Sequence

Polypeptide 316 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rdh12	retinol dehydrogenase 12	15	102	5	5

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117483 Maeda A, et al., Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice. J Biol Chem. 2006 Dec 8;281(49):37697-704
J:156738 Marchette LD, et al., Retinol dehydrogenase 12 detoxifies 4-hydroxynonenal in photoreceptor cells. Free Radic Biol Med. 2010 Jan 1;48(1):16-25
J:188863 Chen C, et al., Reduction of all-trans-retinal in vertebrate rod photoreceptors requires the combined action of RDH8 and RDH12. J Biol Chem. 2012 Jul 13;287(29):24662-70
J:268014 Haeseleer F, et al., Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina. J Biol Chem. 2002 Nov 22;277(47):45537-45546