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Sequence Detail
ID/Version
Q8BUE4 Q8CHZ2 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Ferroptosis suppressor protein 1 {ECO:0000250|UniProtKB:Q9BRQ8}; Short=FSP1 {ECO:0000250|UniProtKB:Q9BRQ8}; EC=1.6.5.- {ECO:0000250|UniProtKB:Q9BRQ8};AltName: Full=Apoptosis-inducing factor homologous mitochondrion-associated
Provider SWISS-PROT
Sequence
Polypeptide 373 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Aifm2 apoptosis-inducing factor, mitochondrion-associated 2 43 98 3 15
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:105660 Mei J, et al., The p53-inducible apoptotic protein AMID is not required for normal development and tumor suppression. Oncogene. 2006 Feb 9;25(6):849-56
J:281212 Miriyala S, et al., Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling. Free Radic Biol Med. 2016 Feb;91:68-80
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:332780 Mishima E, et al., A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Nature. 2022 Aug;608(7924):778-783

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory