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Sequence Detail
ID/Version
Q80WM4 Q80XX2 Q05AB1 (UniProt | EBI) Last sequence update: 2004-05-24
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Hyaluronan and proteoglycan link protein 4;AltName: Full=Brain link protein 2;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 400 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Hapln4 hyaluronan and proteoglycan link protein 4 13 103 3 7
Sequence references in MGI J:83776 Spicer AP, et al., A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links. J Biol Chem. 2003 Jun 6;278(23):21083-91
J:85957 Bekku Y, et al., Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets. Mol Cell Neurosci. 2003 Sep;24(1):148-59
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:263658 Bekku Y, et al., Bral2 is indispensable for the proper localization of brevican and the structural integrity of the perineuronal net in the brainstem and cerebellum. J Comp Neurol. 2012 Jun 1;520(8):1721-36
J:269125 Edamatsu M, et al., Hapln4/Bral2 is a selective regulator for formation and transmission of GABAergic synapses between Purkinje and deep cerebellar nuclei neurons. J Neurochem. 2018 Dec;147(6):748-763

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory