Sequence Detail

ID/Version

Q80W99 Q5FWA9 Q9D5T9 (UniProt | EBI)

Last sequence update: 2007-07-24
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cation channel sperm-associated protein 3; Short=CatSper3;

Provider

SWISS-PROT

Sequence

Polypeptide 395 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Catsper3	cation channel, sperm associated 3	33	97	2	9

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116406 Qi H, et al., All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1219-23
J:117731 Jin JL, et al., Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis. Biol Reprod. 2005 Dec;73(6):1235-42
J:124054 Jin J, et al., Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse. Biol Reprod. 2007 Jul;77(1):37-44
J:182472 Chung JJ, et al., A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa. Nat Commun. 2011 Jan 11;2:153
J:314092 Lin S, et al., Structure of a mammalian sperm cation channel complex. Nature. 2021 Jul;595(7869):746-750
J:321418 Hwang JY, et al., C2cd6-encoded CatSpertau targets sperm calcium channel to Ca(2+) signaling domains in the flagellar membrane. Cell Rep. 2022 Jan 18;38(3):110226
J:354398 Lishko PV, et al., Progesterone activates the principal Ca2+ channel of human sperm. Nature. 2011 Mar 17;471(7338):387-91