Sequence Detail

ID/Version

Q62209 E9QP17 P70192 B2RQK2 Q62329 O09205 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Synaptonemal complex protein 1 {ECO:0000303|PubMed:15944401}; Short=SCP-1;

Provider

SWISS-PROT

Sequence

Polypeptide 993 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sycp1	synaptonemal complex protein 1	45	121	3	9

Sequence references in MGI

J:28808 Sage J, et al., cDNA sequence of the murine synaptonemal complex protein 1 (SCP1). Biochim Biophys Acta. 1995 Sep 19;1263(3):258-60
J:98718 de Vries FA, et al., Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation. Genes Dev. 2005 Jun 1;19(11):1376-89
J:99196 Costa Y, et al., Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the centre of meiosis. J Cell Sci. 2005 Jun 15;118(Pt 12):2755-62
J:111287 Yang F, et al., Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis. J Cell Biol. 2006 May 22;173(4):497-507
J:113188 Hamer G, et al., Characterization of a novel meiosis-specific protein within the central element of the synaptonemal complex. J Cell Sci. 2006 Oct 1;119(Pt 19):4025-32
J:187175 Bisig CG, et al., Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. PLoS Genet. 2012 Jun;8(6):e1002701
J:268520 Zhang Q, et al., Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis. Commun Biol. 2018;1:147
J:277855 Parvanov ED, et al., PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis. Mol Biol Cell. 2017 Feb 1;28(3):488-499
J:285969 Liu H, et al., SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice. Nucleic Acids Res. 2019 Jun 20;47(11):5670-5683
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:297328 Zhang Q, et al., SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I. Sci Adv. 2019 Jan;5(1):eaau9780