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Sequence Detail
Q61091 A2RTK9 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2018-09-12
from provider
RecName: Full=Frizzled-8; Short=Fz-8; Short=mFz8;Flags: Precursor;
Polypeptide 685 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Fzd8 frizzled class receptor 8 46 21 9 3
Sequence references in MGI J:37068 Wang Y, et al., A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem. 1996 Feb 23;271(8):4468-76
J:93897 Lu W, et al., Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell. 2004 Oct 1;119(1):97-108
J:113117 Nam JS, et al., Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem. 2006 May 12;281(19):13247-57
J:114051 Yao R, et al., Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled. Biochem Biophys Res Commun. 2001 Aug 31;286(4):771-8
J:229368 Janda CY, et al., Structural basis of Wnt recognition by Frizzled. Science. 2012 Jul 6;337(6090):59-64

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory