Sequence Detail

ID/Version

Q60809 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=CCR4-NOT transcription complex subunit 7; EC=3.1.13.4;AltName: Full=CCR4-associated factor 1; Short=CAF-1;

Provider

SWISS-PROT

Sequence

Polypeptide 285 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cnot7	CCR4-NOT transcription complex, subunit 7	103	108	3	21

Sequence references in MGI

J:26204 Draper MP, et al., Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex. Mol Cell Biol. 1995 Jul;15(7):3487-95
J:157579 Suzuki A, et al., NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3594-9
J:196089 Fabian MR, et al., Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Mol Cell. 2009 Sep 24;35(6):868-80
J:196241 Zheng X, et al., Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation. Stem Cells. 2012 May;30(5):910-22
J:197524 Rouault JP, et al., Interaction of BTG1 and p53-regulated BTG2 gene products with mCaf1, the murine homolog of a component of the yeast CCR4 transcriptional regulatory complex. J Biol Chem. 1998 Aug 28;273(35):22563-9
J:245369 Yu C, et al., BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes. Nat Struct Mol Biol. 2016 May;23(5):387-94
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89