Sequence Detail

ID/Version

Q5DW34 Q6PGM0 A2AIS4 Q5EBR1 A2AIS3 (UniProt | EBI)

Last sequence update: 2011-03-08
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Histone-lysine N-methyltransferase EHMT1; EC=2.1.1.- {ECO:0000269|PubMed:15774718}; EC=2.1.1.367 {ECO:0000269|PubMed:15774718};AltName: Full=Euchromatic histone-lysine N-methyltransferase 1; Short=Eu-HMTase1;AltName:

Provider

SWISS-PROT

Sequence

Polypeptide 1296 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ehmt1	euchromatic histone methyltransferase 1	42	103	4	103

Sequence references in MGI

J:97244 Tachibana M, et al., Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev. 2005 Apr 1;19(7):815-26
J:143343 Tachibana M, et al., G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J. 2008 Oct 22;27(20):2681-90
J:170429 Levy D, et al., Lysine methylation of the NF-kappaB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-kappaB signaling. Nat Immunol. 2011 Jan;12(1):29-36
J:293487 Yuan J, et al., Two conserved epigenetic regulators prevent healthy ageing. Nature. 2020 Mar;579(7797):118-122
J:338223 Wang J, et al., The MSX1 homeoprotein recruits G9a methyltransferase to repressed target genes in myoblast cells. PLoS One. 2012;7(5):e37647