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Sequence Detail
Q5DTL9 Q9EST0 J7K287 G3F8Y9 I6VS12 E9NX85 G3F8Z0 G3F8Y8 F1DFN1 Q8CFS3 G3F8Y7 (UniProt | EBI) Last sequence update: 2006-07-11
Last annotation update: 2019-10-16
from provider
RecName: Full=Sodium-driven chloride bicarbonate exchanger {ECO:0000303|PubMed:10993873};AltName: Full=Solute carrier family 4 member 10 {ECO:0000312|MGI:MGI:2150150};
Polypeptide 1118 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Slc4a10 solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 45 7 10 6
Sequence references in MGI J:70983 Wang CZ, et al., The Na+-driven Cl-/HCO3- exchanger. Cloning, tissue distribution, and functional characterization. J Biol Chem. 2000 Nov 10;275(45):35486-90
J:87933 Praetorius J, et al., A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells. Am J Physiol Cell Physiol. 2004 Mar;286(3):C601-10
J:94053 Hubner CA, et al., Expression of the sodium-driven chloride bicarbonate exchanger NCBE during prenatal mouse development. Gene Expr Patterns. 2004 Dec;5(2):219-23
J:130810 Chen LM, et al., Use of a new polyclonal antibody to study the distribution and glycosylation of the sodium-coupled bicarbonate transporter NCBE in rodent brain. Neuroscience. 2008 Jan 24;151(2):374-85
J:131058 Jacobs S, et al., Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):311-6
J:191940 Hilgen G, et al., Lack of the sodium-driven chloride bicarbonate exchanger NCBE impairs visual function in the mouse retina. PLoS One. 2012;7(10):e46155
J:239653 Sinning A, et al., Disruption of Slc4a10 augments neuronal excitability and modulates synaptic short-term plasticity. Front Cell Neurosci. 2015;9:223
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:271710 Liu Y, et al., Distribution of NBCn2 (SLC4A10) splice variants in mouse brain. Neuroscience. 2010 Sep 1;169(3):951-64
J:273558 Damkier HH, et al., Na+-dependent HCO3- import by the slc4a10 gene product involves Cl- export. J Biol Chem. 2010 Aug 27;285(35):26998-7007
J:274854 Song X, et al., Neuron type- and input pathway-dependent expression of Slc4a10 in adult mouse brains. Eur J Neurosci. 2014 Sep;40(5):2797-810

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory