Sequence Detail

ID/Version

Q5DTL9 G3F8Y9 I6VS12 E9NX85 G3F8Z0 G3F8Y7 G3F8Y8 J7K287 Q8CFS3 Q9EST0 F1DFN1 (UniProt | EBI)

Last sequence update: 2006-07-11
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Sodium-driven chloride bicarbonate exchanger {ECO:0000303|PubMed:10993873};AltName: Full=Solute carrier family 4 member 10 {ECO:0000312|MGI:MGI:2150150};

Provider

SWISS-PROT

Sequence

Polypeptide 1118 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc4a10	solute carrier family 4, sodium bicarbonate cotransporter-like, member 10	43	108	4	7

Sequence references in MGI

J:70983 Wang CZ, et al., The Na+-driven Cl-/HCO3- exchanger. Cloning, tissue distribution, and functional characterization. J Biol Chem. 2000 Nov 10;275(45):35486-90
J:87933 Praetorius J, et al., A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells. Am J Physiol Cell Physiol. 2004 Mar;286(3):C601-10
J:94053 Hubner CA, et al., Expression of the sodium-driven chloride bicarbonate exchanger NCBE during prenatal mouse development. Gene Expr Patterns. 2004 Dec;5(2):219-23
J:130810 Chen LM, et al., Use of a new polyclonal antibody to study the distribution and glycosylation of the sodium-coupled bicarbonate transporter NCBE in rodent brain. Neuroscience. 2008 Jan 24;151(2):374-85
J:131058 Jacobs S, et al., Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):311-6
J:191940 Hilgen G, et al., Lack of the sodium-driven chloride bicarbonate exchanger NCBE impairs visual function in the mouse retina. PLoS One. 2012;7(10):e46155
J:239653 Sinning A, et al., Disruption of Slc4a10 augments neuronal excitability and modulates synaptic short-term plasticity. Front Cell Neurosci. 2015;9:223
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:271710 Liu Y, et al., Distribution of NBCn2 (SLC4A10) splice variants in mouse brain. Neuroscience. 2010 Sep 1;169(3):951-64
J:273558 Damkier HH, et al., Na+-dependent HCO3- import by the slc4a10 gene product involves Cl- export. J Biol Chem. 2010 Aug 27;285(35):26998-7007
J:274854 Song X, et al., Neuron type- and input pathway-dependent expression of Slc4a10 in adult mouse brains. Eur J Neurosci. 2014 Sep;40(5):2797-810
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89