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Sequence Detail
ID/Version
Q3UZD5 Q3UX75 Q2I2X0 B9EIB0 Q2I2X1 (UniProt | EBI) Last sequence update: 2005-10-11
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Putative histone-lysine N-methyltransferase PRDM6; EC=2.1.1.361 {ECO:0000305|PubMed:17662997};AltName: Full=PR domain zinc finger protein 6;AltName: Full=PR domain-containing protein 6;AltName: Full=PR domain-containing protein in sm
Provider SWISS-PROT
Sequence
Polypeptide 596 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Prdm6 PR domain containing 6 17 102 3 5
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106935 Davis CA, et al., PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells. Mol Cell Biol. 2006 Apr;26(7):2626-36
J:130641 Wu Y, et al., PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation. J Mol Cell Cardiol. 2008 Jan;44(1):47-58
J:252161 Li N, et al., Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. Am J Hum Genet. 2016 Jun 2;98(6):1082-1091

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory