Sequence Detail

ID/Version

P58242 (UniProt | EBI)

Last sequence update: 2001-08-29
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Acid sphingomyelinase-like phosphodiesterase 3b; Short=ASM-like phosphodiesterase 3b; EC=3.1.4.- {ECO:0000269|PubMed:26095358, ECO:0000269|PubMed:27687724};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 456 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Smpdl3b	sphingomyelin phosphodiesterase, acid-like 3B	21	97	3	64

Sequence references in MGI

J:224870 Heinz LX, et al., The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity. Cell Rep. 2015 Jun 30;11(12):1919-28
J:271707 Gorelik A, et al., Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. J Biol Chem. 2016 Nov 11;291(46):24054-24064
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89