Sequence Detail

ID/Version

P51807 Q5M8S6 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Dynein light chain Tctex-type 1;AltName: Full=Activator of G-protein signaling 2; Short=AGS2;AltName: Full=T-complex testis-specific protein 1;AltName: Full=TCTEX-1;

Provider

SWISS-PROT

Sequence

Polypeptide 113 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dynlt1b	dynein light chain Tctex-type 1B	49	103	3	1

Sequence references in MGI

J:9988 Lader E, et al., tctex-1: a candidate gene family for a mouse t complex sterility locus. Cell. 1989 Sep 8;58(5):969-79
J:69001 Mok YK, et al., Structure of Tctex-1 and its interaction with cytoplasmic dynein intermediate chain. J Biol Chem. 2001 Apr 27;276(17):14067-74
J:76904 DiBella LM, et al., The Tctex1/Tctex2 class of dynein light chains. Dimerization, differential expression, and interaction with the LC8 protein family. J Biol Chem. 2001 Apr 27;276(17):14366-73
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:161097 Gauthier-Fisher A, et al., Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells. Nat Neurosci. 2009 Jun;12(6):735-44
J:233943 Takesono A, et al., Receptor-independent activators of heterotrimeric G-protein signaling pathways. J Biol Chem. 1999 Nov 19;274(47):33202-5
J:289069 Zhang Y, et al., Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat. J Mol Cell Biol. 2019 May 1;11(5):383-394
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:319365 Liu S, et al., CFAP61 is required for sperm flagellum formation and male fertility in human and mouse. Development. 2021 Dec 1;148(23):dev199805