Sequence Detail

ID/Version

P49769 P49769 Q91WK6 (UniProt | EBI)

Last sequence update: 1996-10-01 Last annotation update: 2013-02-06

Sequence description from provider

RecName: Full=Presenilin-1; Short=PS-1; EC=3.4.23.-;AltName: Full=Protein S182;Contains: RecName: Full=Presenilin-1 NTF subunit;Contains: RecName: Full=Presenilin-1 CTF subunit;Contains: RecName: Full=Presenilin-1 CTF12; Short

Provider

SWISS-PROT

Sequence

Polypeptide 467 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Psen1	presenilin 1	187	8	6	34

Sequence references in MGI

J:37100 Sherrington R, et al., Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease [see comments]. Nature. 1995 Jun 29;375(6534):754-60
J:43028 Mitsuda N, et al., Transcriptional regulation of the mouse presenilin-1 gene. J Biol Chem. 1997 Sep 19;272(38):23489-97
J:79164 Kashiwa A, et al., Isolation and characterization of novel presenilin binding protein. J Neurochem. 2000 Jul;75(1):109-16
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54