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Sequence Detail
ID/Version
P49769 Q9JLP9 Q91WK6 (UniProt | EBI) Last sequence update: 1996-10-01
Last annotation update: 2014-03-19
Sequence
description
from provider
RecName: Full=Presenilin-1; Short=PS-1; EC=3.4.23.-;AltName: Full=Protein S182;Contains: RecName: Full=Presenilin-1 NTF subunit;Contains: RecName: Full=Presenilin-1 CTF subunit;Contains: RecName: Full=Presenilin-1 CTF12; Short
Provider SWISS-PROT
Sequence
Polypeptide 467 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Psen1 presenilin 1 193 8 6 35
Sequence references in MGI J:37100 Sherrington R, et al., Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease [see comments]. Nature. 1995 Jun 29;375(6534):754-60
J:43028 Mitsuda N, et al., Transcriptional regulation of the mouse presenilin-1 gene. J Biol Chem. 1997 Sep 19;272(38):23489-97
J:79164 Kashiwa A, et al., Isolation and characterization of novel presenilin binding protein. J Neurochem. 2000 Jul;75(1):109-16
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory