Sequence Detail

ID/Version

P45376 O70130 Q99KC9 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Aldo-keto reductase family 1 member B1; EC=1.1.1.300 {ECO:0000250|UniProtKB:P15121}; EC=1.1.1.372 {ECO:0000250|UniProtKB:P15121}; EC=1.1.1.54 {ECO:0000250|UniProtKB:P15121};AltName: Full=Aldehyde reductase;AltName: Fu

Provider

SWISS-PROT

Sequence

Polypeptide 316 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Akr1b1	aldo-keto reductase family 1 member B	58	101	4	11

Sequence references in MGI

J:23037 Gui T, et al., Presence of a closely related subgroup in the aldo-ketoreductase family of the mouse. Eur J Biochem. 1995 Jan 15;227(1-2):448-53
J:47521 McGowan MH, et al., Characterization of the mouse aldose reductase gene and promoter in a lens epithelial cell line. Mol Vis. 1998 Jan 28;4:2
J:53108 Ho HT, et al., Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes. Eur J Biochem. 1999 Feb;259(3):726-30
J:53268 Li H, et al., Characterization of genomic regions directing the cell-specific expression of the mouse aldose reductase gene. Biochem Biophys Res Commun. 1999 Feb 24;255(3):759-64
J:77647 Ho HT, et al., Aldose reductase-deficient mice develop nephrogenic diabetes insipidus. Mol Cell Biol. 2000 Aug;20(16):5840-6
J:125596 Spite M, et al., Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes. Biochem J. 2007 Jul 1;405(1):95-105
J:149086 Kabututu Z, et al., Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7. J Biochem. 2009 Feb;145(2):161-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89