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Sequence Detail
P22599 Q80ZH5 Q61283 Q8VC20 (UniProt | EBI) Last sequence update: 2005-06-21
Last annotation update: 2019-06-05
from provider
RecName: Full=Alpha-1-antitrypsin 1-2; Short=AAT;AltName: Full=Alpha-1 protease inhibitor 2;AltName: Full=Alpha-1-antiproteinase;AltName: Full=Serine protease inhibitor 1-2;AltName: Full=Serine protease inhibitor A1b; Short=Serpin A1b;Flag
Polypeptide 413 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Serpina1b serine (or cysteine) preptidase inhibitor, clade A, member 1B 22 2 15 2
Sequence references in MGI J:10300 Sifers RN, et al., Complete cDNA sequence and chromosomal localization of mouse alpha 1-antitrypsin. Genomics. 1990 Jan;6(1):100-4
J:23546 Borriello F, et al., Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9417-21
J:31321 Paterson T, et al., The expression and characterization of five recombinant murine alpha 1-protease inhibitor proteins. Biochem Biophys Res Commun. 1996 Feb 6;219(1):64-9
J:76390 Barbour KW, et al., Functional Diversification During Evolution of the Murine alpha(1)-Proteinase Inhibitor Family: Role of the Hypervariable Reactive Center Loop. Mol Biol Evol. 2002 May;19(5):718-27
J:80096 Barbour KW, et al., The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure. Genomics. 2002 Nov;80(5):515-22
J:82699 Forsyth S, et al., A review and comparison of the murine alpha(1)-antitrypsin and alpha(1)-antichymotrypsin multigene clusters with the human clade A serpins. Genomics. 2003 Mar;81(3):336-45

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory