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Sequence Detail
ID/Version
P22315 (UniProt | EBI) Last sequence update: 1991-11-01
Last annotation update: 2014-10-01
Sequence
description
from provider
RecName: Full=Ferrochelatase, mitochondrial; EC=4.99.1.1;AltName: Full=Heme synthase;AltName: Full=Protoheme ferro-lyase;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 420 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Fech ferrochelatase 36 2 4 4
Sequence references in MGI J:10830 Taketani S, et al., Molecular cloning, sequencing, and expression of mouse ferrochelatase. J Biol Chem. 1990 Nov 15;265(32):19377-80
J:10979 Brenner DA, et al., Cloning of murine ferrochelatase. Proc Natl Acad Sci U S A. 1991 Feb 1;88(3):849-53
J:12757 Boulechfar S, et al., Ferrochelatase structural mutant (Fechm1Pas) in the house mouse. Genomics. 1993 Jun;16(3):645-8
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory