Sequence Detail

ID/Version

P17433 Q99L57 (UniProt | EBI)

Last sequence update: 2005-02-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Transcription factor PU.1 {ECO:0000303|PubMed:2180582};AltName: Full=31 kDa-transforming protein;AltName: Full=SFFV proviral integration 1 protein;

Provider

SWISS-PROT

Sequence

Polypeptide 272 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Spi1	Spi-1 proto-oncogene	112	121	4	47

Sequence references in MGI

J:10149 Moreau-Gachelin F, et al., The putative oncogene Spi-1: murine chromosomal localization and transcriptional activation in murine acute erythroleukemias [published erratum appears in Oncogene 1990 Jun;5(6):941]. Oncogene. 1989 Dec;4(12):1449-56
J:10374 Klemsz MJ, et al., The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene [see comments]. Cell. 1990 Apr 6;61(1):113-24
J:10894 Paul R, et al., The Sfpi-1 proviral integration site of Friend erythroleukemia encodes the ets-related transcription factor Pu.1. J Virol. 1991 Jan;65(1):464-7
J:20348 Scott EW, et al., Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science. 1994 Sep 9;265(5178):1573-7
J:113820 Hallier M, et al., The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrb. J Biol Chem. 1996 May 10;271(19):11177-81
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:175175 Dahl R, et al., The transcriptional repressor GFI-1 antagonizes PU.1 activity through protein-protein interaction. J Biol Chem. 2007 Mar 2;282(9):6473-83