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Sequence Detail
P17433 Q99L57 (UniProt | EBI) Last sequence update: 2005-02-01
Last annotation update: 2021-06-02
from provider
RecName: Full=Transcription factor PU.1;AltName: Full=31 kDa-transforming protein;AltName: Full=SFFV proviral integration 1 protein;
Polypeptide 272 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Spi1 spleen focus forming virus (SFFV) proviral integration oncogene 108 107 4 43
Sequence references in MGI J:10149 Moreau-Gachelin F, et al., The putative oncogene Spi-1: murine chromosomal localization and transcriptional activation in murine acute erythroleukemias [published erratum appears in Oncogene 1990 Jun;5(6):941]. Oncogene. 1989 Dec;4(12):1449-56
J:10374 Klemsz MJ, et al., The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene [see comments]. Cell. 1990 Apr 6;61(1):113-24
J:10894 Paul R, et al., The Sfpi-1 proviral integration site of Friend erythroleukemia encodes the ets-related transcription factor Pu.1. J Virol. 1991 Jan;65(1):464-7
J:113820 Hallier M, et al., The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrb. J Biol Chem. 1996 May 10;271(19):11177-81
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:175175 Dahl R, et al., The transcriptional repressor GFI-1 antagonizes PU.1 activity through protein-protein interaction. J Biol Chem. 2007 Mar 2;282(9):6473-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory