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Sequence Detail
P11344 (UniProt | EBI) Last sequence update: 2007-05-29
Last annotation update: 2017-11-22
from provider
RecName: Full=Tyrosinase; EC=;AltName: Full=Albino locus protein;AltName: Full=Monophenol monooxygenase;Flags: Precursor;
Polypeptide 533 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Tyr tyrosinase 30 11 9 229
Sequence references in MGI J:1962 Tsukamoto K, et al., A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. EMBO J. 1992 Feb;11(2):519-26
J:9242 Kwon BS, et al., Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression. Biochem Biophys Res Commun. 1988 Jun 30;153(3):1301-9
J:9824 Kwon BS, et al., Molecular basis of mouse Himalayan mutation. Biochem Biophys Res Commun. 1989 May 30;161(1):252-60
J:10058 Kwon BS, et al., Isolation, chromosomal mapping, and expression of the mouse tyrosinase gene. J Invest Dermatol. 1989 Nov;93(5):589-94
J:10488 Shibahara S, et al., A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine----serine substitution at position 85. Eur J Biochem. 1990 Apr 30;189(2):455-61
J:18122 Terao M, et al., Isolation and characterization of variant cDNAs encoding mouse tyrosinase. Biochem Biophys Res Commun. 1989 Mar 15;159(2):848-53
J:19279 Beermann F, et al., Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice. EMBO J. 1990 Sep;9(9):2819-26
J:32467 Muller G, et al., Functional analysis of alternatively spliced tyrosinase gene transcripts. EMBO J. 1988 Sep;7(9):2723-30
J:230050 Marubashi S, et al., RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes. J Biol Chem. 2016 Jan 15;291(3):1427-40

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last database update
MGI 6.12
The Jackson Laboratory