Sequence Detail

ID/Version

P09925 Q99KB4 Q9DCU5 (UniProt | EBI)

Last sequence update: 2002-06-06
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Surfeit locus protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 306 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Surf1	surfeit gene 1	12	99	3	5

Sequence references in MGI

J:29566 Williams TJ, et al., The MES-1 murine enhancer element is closely associated with the heterogeneous 5' ends of two divergent transcription units. Mol Cell Biol. 1986 Dec;6(12):4558-69
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117871 Dell'agnello C, et al., Increased longevity and refractoriness to Ca2+-dependent neurodegeneration in Surf1 knockout mice. Hum Mol Genet. 2007 Feb 15;16(4):431-44
J:192149 Stettner GM, et al., Hypoxic and hypercapnic challenges unveil respiratory vulnerability of Surf1 knockout mice, an animal model of Leigh syndrome. Mitochondrion. 2011 May;11(3):413-20
J:248388 Pulliam DA, et al., Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses. Biochem J. 2014 Sep 1;462(2):359-71
J:284999 Lin AL, et al., Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice. J Cereb Blood Flow Metab. 2013 Oct;33(10):1605-11
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89