Sequence Detail

ID/Version

O88967 Q7TNN5 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=ATP-dependent zinc metalloprotease YME1L1; EC=3.4.24.- {ECO:0000269|PubMed:27495975};AltName: Full=ATP-dependent metalloprotease FtsH1;AltName: Full=YME1-like protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 715 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Yme1l1	YME1-like 1 (S. cerevisiae)	30	96	4	42

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:215813 Anand R, et al., The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission. J Cell Biol. 2014 Mar 17;204(6):919-29
J:229455 Wai T, et al., Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice. Science. 2015 Dec 4;350(6265):aad0116
J:235613 Hartmann B, et al., Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation. Elife. 2016;5:e16078
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89