Sequence Detail

ID/Version

O88491 Q8C480 Q9CT70 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Histone-lysine N-methyltransferase, H3 lysine-36 specific; EC=2.1.1.357 {ECO:0000269|PubMed:12805229};AltName: Full=H3-K36-HMTase;AltName: Full=Nuclear receptor-binding SET domain-containing protein 1; Short=NR-binding SET do

Provider

SWISS-PROT

Sequence

Polypeptide 2588 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nsd1	nuclear receptor-binding SET-domain protein 1	42	105	4	324

Sequence references in MGI

J:48279 Huang N, et al., Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO J. 1998 Jun 15;17(12):3398-412
J:83923 Rayasam GV, et al., NSD1 is essential for early post-implantation development and has a catalytically active SET domain. EMBO J. 2003 Jun 16;22(12):3153-63
J:91024 Nielsen AL, et al., Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif. Mol Cell Biol. 2004 Jun;24(12):5184-96
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89