Sequence Detail

ID/Version

O54908 Q80UL5 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Dickkopf-related protein 1; Short=Dickkopf-1; Short=Dkk-1; Short=mDkk-1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 272 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dkk1	dickkopf WNT signaling pathway inhibitor 1	74	167	4	22

Sequence references in MGI

J:51745 Glinka A, et al., Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 1998 Jan 22;391(6665):357-62
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:137914 Ellwanger K, et al., Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Mol Cell Biol. 2008 Aug;28(15):4875-82
J:240374 Causeret F, et al., Kremen1 and Dickkopf1 control cell survival in a Wnt-independent manner. Cell Death Differ. 2016 Feb;23(2):323-32