Sequence Detail

ID/Version

O08710 Q2NKY1 O88590 Q9QWY7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Thyroglobulin; Short=Tg;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 2766 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tg	thyroglobulin	28	118	3	21

Sequence references in MGI

J:8567 Beamer WG, et al., Inherited congenital goiter in mice. Endocrinology. 1987 Feb;120(2):838-40
J:43991 Caturegli P, et al., Cloning and characterization of murine thyroglobulin cDNA. Clin Immunol Immunopathol. 1997 Nov;85(2):221-6
J:49474 Kim PS, et al., A single amino acid change in the acetylcholinesterase-like domain of thyroglobulin causes congenital goiter with hypothyroidism in the cog/cog mouse: a model of human endoplasmic reticulum storage diseases. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9909-13
J:83877 Friedrichs B, et al., Thyroid functions of mouse cathepsins B, K, and L. J Clin Invest. 2003 Jun;111(11):1733-45
J:281193 Lee J, et al., The cholinesterase-like domain, essential in thyroglobulin trafficking for thyroid hormone synthesis, is required for protein dimerization. J Biol Chem. 2009 May 8;284(19):12752-61