Sequence Detail

ID/Version

E9PV24 Q99K47 (UniProt | EBI)

Last sequence update: 2011-04-05
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Fibrinogen alpha chain;Contains: RecName: Full=Fibrinopeptide A {ECO:0000250|UniProtKB:P06399};Contains: RecName: Full=Fibrinogen alpha chain;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 789 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fga	fibrinogen alpha chain	46	102	3	16

Sequence references in MGI

J:28436 Suh TT, et al., Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice. Genes Dev. 1995 Aug 15;9(16):2020-33
J:63750 Ni H, et al., Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest. 2000 Aug;106(3):385-92
J:69961 Drew AF, et al., Wound-healing defects in mice lacking fibrinogen. Blood. 2001 Jun 15;97(12):3691-8
J:99283 Mullarky IK, et al., Infection-stimulated fibrin deposition controls hemorrhage and limits hepatic bacterial growth during listeriosis. Infect Immun. 2005 Jul;73(7):3888-95
J:150774 Yang H, et al., Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression. Blood. 2009 Jul 9;114(2):425-36
J:194888 Luo D, et al., Fibrin Facilitates Both Innate and T Cell-Mediated Defense against Yersinia pestis. J Immunol. 2013 Apr 15;190(8):4149-61
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89