Sequence Detail

ID/Version

A1KXC4 A1KXC8 Q148B9 A1KXC9 Q9D8T1 A1KXC6 (UniProt | EBI)

Last sequence update: 2007-04-17
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Immunoglobulin mu Fc receptor {ECO:0000250|UniProtKB:O60667}; Short=IgM FcR {ECO:0000250|UniProtKB:O60667};AltName: Full=Fas apoptotic inhibitory molecule 3 {ECO:0000250|UniProtKB:O60667}; Short=FAIM3 {ECO:0000303|PubMed:3478

Provider

SWISS-PROT

Sequence

Polypeptide 422 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fcmr	Fc fragment of IgM receptor	28	96	2	15

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:190113 Ouchida R, et al., Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):E2699-706
J:192603 Choi SC, et al., Mouse IgM Fc Receptor, FCMR, Promotes B Cell Development and Modulates Antigen-Driven Immune Responses. J Immunol. 2013 Feb 1;190(3):987-96
J:240689 Nguyen TT, et al., The IgM receptor FcmuR limits tonic BCR signaling by regulating expression of the IgM BCR. Nat Immunol. 2017 Mar;18(3):321-333
J:262882 Yu J, et al., Surface receptor Toso controls B cell-mediated regulation of T cell immunity. J Clin Invest. 2018 May 1;128(5):1820-1836
J:340662 Rochereau N, et al., Essential role of TOSO/FAIM3 in intestinal IgM reverse transcytosis. Cell Rep. 2021 Nov 16;37(7):110006