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Query Results -- Summary
69 matching items displayed in reverse chronological order

J:147068, Fleming CE; Mar FM; Franquinho F; Saraiva MJ; Sousa MM, Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity., J Neurosci 2009 Mar 11;29(10):3220-32

J:149003, Spoelgen R; Adams KW; Koker M; Thomas AV; Andersen OM; Hallett PJ; Bercury KK; Joyner DF; Deng M; Stoothoff WH; Strickland DK; Willnow TE; Hyman BT, Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11., Neuroscience 2009 Feb 18;158(4):1460-8

J:151683, Parreira KS; Debaix H; Cnops Y; Geffers L; Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability., Pflugers Arch 2009 Aug;458(4):745-59

J:136759, Zhang H; Yoshioka S; Miyazaki M; Kannagi R; Suzuki A, Core 2 GlcNAc modification and megalin ligand-binding activity., Biochim Biophys Acta 2008 Mar;1780(3):479-85

J:130836, Gerbe F; Cox B; Rossant J; Chazaud C, Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst., Dev Biol 2008 Jan 15;313(2):594-602

J:134797, Konig O; Ruttiger L; Muller M; Zimmermann U; Erdmann B; Kalbacher H; Gross M; Knipper M, Estrogen and the inner ear: megalin knockout mice suffer progressive hearing loss., FASEB J 2008 Feb;22(2):410-7

J:133662, Olson GE; Winfrey VP; Hill KE; Burk RF, Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells., J Biol Chem 2008 Mar 14;283(11):6854-60

J:152876, Gailly P; Jouret F; Martin D; Debaix H; Parreira KS; Nishita T; Blanchard A; Antignac C; Willnow TE; Courtoy PJ; Scheinman SJ; Christensen EI; Devuyst O, A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunction., Kidney Int 2008 Jul;74(1):52-61

J:136110, Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals), MGI Direct Data Submission 2008;():

J:136621, Wicher G; Aldskogius H, Megalin deficiency induces critical changes in mouse spinal cord development., Neuroreport 2008 Mar 26;19(5):559-63

J:121774, Kaseda R; Iino N; Hosojima M; Takeda T; Hosaka K; Kobayashi A; Yamamoto K; Suzuki A; Kasai A; Suzuki Y; Gejyo F; Saito A, Megalin-mediated endocytosis of cystatin C in proximal tubule cells., Biochem Biophys Res Commun 2007 Jun 15;357(4):1130-4

J:123312, Kurumada S; Onishi A; Imai H; Ishii K; Kobayashi T; Sato SB, Stage-specific association of apolipoprotein A-I and E in developing mouse retina., Invest Ophthalmol Vis Sci 2007 Apr;48(4):1815-23

J:150247, Theilig F; Kriz W; Jerichow T; Schrade P; Hahnel B; Willnow T; Le Hir M; Bachmann S, Abrogation of protein uptake through megalin-deficient proximal tubules does not safeguard against tubulointerstitial injury., J Am Soc Nephrol 2007 Jun;18(6):1824-34

J:121266, Yang DH; Cai KQ; Roland IH; Smith ER; Xu XX, Disabled-2 is an epithelial surface positioning gene., J Biol Chem 2007 Apr 27;282(17):13114-22

J:120117, Nielsen R; Courtoy PJ; Jacobsen C; Dom G; Lima WR; Jadot M; Willnow TE; Devuyst O; Christensen EI, Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells., Proc Natl Acad Sci U S A 2007 Mar 27;104(13):5407-12

J:108391, Gonzalez-Villalobos R; Klassen RB; Allen PL; Johanson K; Baker CB; Kobori H; Navar LG; Hammond TG, Megalin binds and internalizes angiotensin-(1-7)., Am J Physiol Renal Physiol 2006 May;290(5):F1270-5

J:119685, Smith BT; Mussell JC; Fleming PA; Barth JL; Spyropoulos DD; Cooley MA; Drake CJ; Argraves WS, Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formation., BMC Dev Biol 2006;6():30

J:104891, Osafune K; Takasato M; Kispert A; Asashima M; Nishinakamura R, Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay., Development 2006 Jan;133(1):151-61

J:104065, Faber K; Hvidberg V; Moestrup SK; Dahlback B; Nielsen LB, Megalin is a receptor for apolipoprotein M, and kidney-specific megalin-deficiency confers urinary excretion of apolipoprotein M., Mol Endocrinol 2006 Jan;20(1):212-8

J:117102, Zheng B; Tang T; Tang N; Kudlicka K; Ohtsubo K; Ma P; Marth JD; Farquhar MG; Lehtonen E, Essential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics., Proc Natl Acad Sci U S A 2006 Nov 7;103(45):16776-81

J:100535, Nagai J; Christensen EI; Morris SM; Willnow TE; Cooper JA; Nielsen R, Mutually dependent localization of megalin and Dab2 in the renal proximal tubule., Am J Physiol Renal Physiol 2005 Sep;289(3):F569-76

J:98256, Assemat E; Vinot S; Gofflot F; Linsel-Nitschke P; Illien F; Chatelet F; Verroust P; Louvet-Vallee S; Rinninger F; Kozyraki R, Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo., Biol Reprod 2005 May;72(5):1079-86

J:115189, Hammes A; Andreassen TK; Spoelgen R; Raila J; Hubner N; Schulz H; Metzger J; Schweigert FJ; Luppa PB; Nykjaer A; Willnow TE, Role of endocytosis in cellular uptake of sex steroids., Cell 2005 Sep 9;122(5):751-62

J:95319, Spoelgen R; Hammes A; Anzenberger U; Zechner D; Andersen OM; Jerchow B; Willnow TE, LRP2/megalin is required for patterning of the ventral telencephalon., Development 2005 Jan;132(2):405-14

J:150394, Jouret F; Auzanneau C; Debaix H; Wada GH; Pretto C; Marbaix E; Karet FE; Courtoy PJ; Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis., J Am Soc Nephrol 2005 Nov;16(11):3235-46

J:103780, Maurer ME; Cooper JA, Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein., J Cell Sci 2005 Nov 15;118(Pt 22):5345-55

J:104562, Wicher G; Larsson M; Rask L; Aldskogius H, Low-density lipoprotein receptor-related protein (LRP)-2/megalin is transiently expressed in a subpopulation of neural progenitors in the embryonic mouse spinal cord., J Comp Neurol 2005 Nov 14;492(2):123-31

J:102869, Raila J; Willnow TE; Schweigert FJ, Megalin-mediated reuptake of retinol in the kidneys of mice is essential for vitamin a homeostasis., J Nutr 2005 Nov;135(11):2512-6

J:104823, Lisi S; Segnani C; Mattii L; Botta R; Marcocci C; Dolfi A; McCluskey RT; Pinchera A; Bernardini N; Marino M, Thyroid dysfunction in megalin deficient mice., Mol Cell Endocrinol 2005 May 31;236(1-2):43-7

J:99680, The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome, Science 2005;309(5740):1559-1563

J:88400, Drake CJ; Fleming PA; Larue AC; Barth JL; Chintalapudi MR; Argraves WS, Differential distribution of cubilin and megalin expression in the mouse embryo., Anat Rec A Discov Mol Cell Evol Biol 2004 Mar;277(1):163-70

J:93296, Yu H; Wessels A; Chen J; Phelps AL; Oatis J; Tint GS; Patel SB, Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome., BMC Dev Biol 2004 Mar 2;4(1):1

J:98337, Strope S; Rivi R; Metzger T; Manova K; Lacy E, Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules., Development 2004 Oct;131(19):4787-95

J:102349, Bachmann S; Schlichting U; Geist B; Mutig K; Petsch T; Bacic D; Wagner CA; Kaissling B; Biber J; Murer H; Willnow TE, Kidney-specific inactivation of the megalin gene impairs trafficking of renal inorganic sodium phosphate cotransporter (NaPi-IIa)., J Am Soc Nephrol 2004 Apr;15(4):892-900

J:90197, Marschang P; Brich J; Weeber EJ; Sweatt JD; Shelton JM; Richardson JA; Hammer RE; Herz J, Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1., Mol Cell Biol 2004 May;24(9):3782-93

J:136795, Zarbalis K; May SR; Shen Y; Ekker M; Rubenstein JL; Peterson AS, A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development., PLoS Biol 2004 Aug;2(8):E219

J:81496, Leheste JR; Melsen F; Wellner M; Jansen P; Schlichting U; Renner-Muller I; Andreassen TT; Wolf E; Bachmann S; Nykjaer A; Willnow TE, Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect., FASEB J 2003 Feb;17(2):247-9

J:82078, Petersen HH; Hilpert J; Militz D; Zandler V; Jacobsen C; Roebroek AJ; Willnow TE, Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule., J Cell Sci 2003 Feb 1;116(Pt 3):453-61

J:91812, Stryke D; Kawamoto M; Huang CC; Johns SJ; King LA; Harper CA; Meng EC; Lee RE; Yee A; L'Italien L; Chuang PT; Young SG; Skarnes WC; Babbitt PC; Ferrin TE, BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic Acids Res 2003 Jan 1;31(1):278-81

J:85162, Hansen J; Floss T; Van Sloun P; Fuchtbauer EM; Vauti F; Arnold HH; Schnutgen F; Wurst W; von Melchner H; Ruiz P, A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome., Proc Natl Acad Sci U S A 2003 Aug 19;100(17):9918-22

J:84433, Christensen EI; Devuyst O; Dom G; Nielsen R; Van der Smissen P; Verroust P; Leruth M; Guggino WB; Courtoy PJ, Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules., Proc Natl Acad Sci U S A 2003 Jul 8;100(14):8472-7

J:86696, Zambrowicz BP; Abuin A; Ramirez-Solis R; Richter LJ; Piggott J; BeltrandelRio H; Buxton EC; Edwards J; Finch RA; Friddle CJ; Gupta A; Hansen G; Hu Y; Huang W; Jaing C; Key BW Jr; Kipp P; Kohlhauff B; Ma ZQ; Markesich D; Payne R; Potter DG; Qian N; Shaw J; Schrick J; Shi ZZ; Sparks MJ; Van Sligtenhorst I; Vogel P; Walke W; Xu N; Zhu Q; Person C; Sands AT, Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention., Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14109-14

J:75593, Birn H; Willnow TE; Nielsen R; Norden AG; Bonsch C; Moestrup SK; Nexo E; Christensen EI, Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B(12)., Am J Physiol Renal Physiol 2002 Mar;282(3):F408-16

J:79862, Yang DH; Smith ER; Roland IH; Sheng Z; He J; Martin WD; Hamilton TC; Lambeth JD; Xu XX, Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis., Dev Biol 2002 Nov 1;251(1):27-44

J:80000, The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs, Nature 2002;420():563-573

J:66998, Lammert F; Carey MC; Paigen B, Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map., Gastroenterology 2001 Jan;120(1):221-38

J:74182, Legallicier B; Trugnan G; Murphy G; Lelongt B; Ronco P, Expression of the type IV collagenase system during mouse kidney development and tubule segmentation., J Am Soc Nephrol 2001 Nov;12(11):2358-69

J:67137, Hammad SM; Barth JL; Knaak C; Argraves WS, Mus musculus low density lipoprotein receptor-related protein 2 LRP2 (Lrp2) mRNA, partial cds, GenBank Submission 2000;():AF197160

J:103160, Birn H; Vorum H; Verroust PJ; Moestrup SK; Christensen EI, Receptor-associated protein is important for normal processing of megalin in kidney proximal tubules., J Am Soc Nephrol 2000 Feb;11(2):191-202

J:67664, Hammad SM; Barth JL; Knaak C; Argraves WS, Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins., J Biol Chem 2000 Apr 21;275(16):12003-8

J:113901, Gotthardt M; Trommsdorff M; Nevitt MF; Shelton J; Richardson JA; Stockinger W; Nimpf J; Herz J, Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction., J Biol Chem 2000 Aug 18;275(33):25616-24

J:120568, Birn H; Fyfe JC; Jacobsen C; Mounier F; Verroust PJ; Orskov H; Willnow TE; Moestrup SK; Christensen EI, Cubilin is an albumin binding protein important for renal tubular albumin reabsorption., J Clin Invest 2000 May;105(10):1353-61

J:108230, Leheste JR; Rolinski B; Vorum H; Hilpert J; Nykjaer A; Jacobsen C; Aucouturier P; Moskaug JO; Otto A; Christensen EI; Willnow TE, Megalin knockout mice as an animal model of low molecular weight proteinuria., Am J Pathol 1999 Oct;155(4):1361-70

J:103285, Niemeier A; Willnow T; Dieplinger H; Jacobsen C; Meyer N; Hilpert J; Beisiegel U, Identification of megalin/gp330 as a receptor for lipoprotein(a) in vitro., Arterioscler Thromb Vasc Biol 1999 Mar;19(3):552-61

J:53162, Nykjaer A; Dragun D; Walther D; Vorum H; Jacobsen C; Herz J; Melsen F; Christensen EI; Willnow TE, An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3., Cell 1999 Feb 19;96(4):507-15

J:103274, Christensen EI; Moskaug JO; Vorum H; Jacobsen C; Gundersen TE; Nykjaer A; Blomhoff R; Willnow TE; Moestrup SK, Evidence for an essential role of megalin in transepithelial transport of retinol., J Am Soc Nephrol 1999 Apr;10(4):685-95

J:42314, Klingenspor M; Xu P; Cohen RD; Welch C; Reue K, Altered gene expression pattern in the fatty liver dystrophy mouse reveals impaired insulin-mediated cytoskeleton dynamics., J Biol Chem 1999 Aug 13;274(33):23078-84

J:59629, Lehtonen S; Riento K; Olkkonen VM; Lehtonen E, Syntaxin 3 and Munc-18-2 in epithelial cells during kidney development., Kidney Int 1999 Sep;56(3):815-26

J:58190, Bouchard G; Nelson HM; Lammert F; Rowe LB; Carey MC; Paigen B, High-resolution maps of the murine Chromosome 2 region containing the cholesterol gallstone locus, Lith1., Mamm Genome 1999 Nov;10(11):1070-4

J:46905, Moll S; Menoud PA; French L; Sappino AP; Pastore Y; Schifferli JA; Izui S, Tubular up-regulation of clusterin mRNA in murine lupus-like nephritis., Am J Pathol 1998 Apr;152(4):953-62

J:48038, Mehrabian M; Wen PZ; Fisler J; Davis RC; Lusis AJ, Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model., J Clin Invest 1998 Jun 1;101(11):2485-96

J:115131, Moestrup SK; Schousboe I; Jacobsen C; Leheste JR; Christensen EI; Willnow TE, beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin., J Clin Invest 1998 Sep 1;102(5):902-9

J:40697, Briquet-Laugier V; Xia YR; Rooke K; Mehrabian M; Lusis AJ; Doolittle MH, Mapping of three members of the mouse protein disulfide isomerase family., Mamm Genome 1998 Feb;9(2):176-7

J:39021, Jiang Y; Yu VC; Buchholz F; O'Connell S; Rhodes SJ; Candeloro C; Xia YR; Lusis AJ; Rosenfeld MG, A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland., J Biol Chem 1996 May 3;271(18):10723-30

J:34178, Welch CL; Xia YR; Shechter I; Farese R; Mehrabian M; Mehdizadeh S; Warden CH; Lusis AJ, Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes., J Lipid Res 1996 Jul;37(7):1406-21

J:34835, Willnow TE; Hilpert J; Armstrong SA; Rohlmann A; Hammer RE; Burns DK; Herz J, Defective forebrain development in mice lacking gp330/megalin., Proc Natl Acad Sci U S A 1996 Aug 6;93(16):8460-4

J:28745, Chowdhary BP; Lundgren S; Johansson M; Hjalm G; Akerstrom G; Gustavsson I; Rask L, In situ hybridization mapping of a 500-kDa calcium-sensing protein gene (LRP2) to human chromosome region 2q31-->q32.1 and porcine chromosome region 15q22-->q24., Cytogenet Cell Genet 1995;71(2):120-3

J:21620, Gueth-Hallonet C; Santa-Maria A; Verroust P; Maro B, Gp330 is specifically expressed in outer cells during epithelial differentiation in the preimplantation mouse embryo., Development 1994 Nov;120(11):3289-99

J:14575, Xia YR; Bachinsky DR; Smith JA; McCluskey RT; Warden CH; Lusis AJ, Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2., Genomics 1993 Sep;17(3):780-1


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