155 matching items displayed in reverse chronological order

J:148952, Rowbotham NJ; Hager-Theodorides AL; Furmanski AL; Ross SE; Outram SV; Dessens JT; Crompton T, Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanism., Blood 2009 May 21;113(21):5144-56

J:149309, Ward RJ; Lee L; Graham K; Satkunendran T; Yoshikawa K; Ling E; Harper L; Austin R; Nieuwenhuis E; Clarke ID; Hui CC; Dirks PB, Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma., Cancer Res 2009 Jun 1;69(11):4682-90

J:152817, Sehgal R; Sheibani N; Rhodes SJ; Belecky Adams TL, BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression., Dev Biol 2009 Aug 15;332(2):429-43

J:145182, Pan Y; Wang C; Wang B, Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development., Dev Biol 2009 Feb 1;326(1):177-89

J:153550, Yu W; Wang Y; McDonnell K; Stephen D; Bai CB, Patterning of ventral telencephalon requires positive function of Gli transcription factors., Dev Biol 2009 Oct 1;334(1):264-75

J:153098, Goss AM; Tian Y; Tsukiyama T; Cohen ED; Zhou D; Lu MM; Yamaguchi TP; Morrisey EE, Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut., Dev Cell 2009 Aug;17(2):290-8

J:153731, Pazin DE; Albrecht KH, Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation., Dev Dyn 2009 Nov;238(11):2877-90

J:154979, Miyagawa S; Moon A; Haraguchi R; Inoue C; Harada M; Nakahara C; Suzuki K; Matsumaru D; Kaneko T; Matsuo I; Yang L; Taketo MM; Iguchi T; Evans SM; Yamada G, Dosage-dependent hedgehog signals integrated with Wnt/{beta}-catenin signaling regulate external genitalia formation as an appendicular program., Development 2009 Dec;136(23):3969-78

J:144016, Ribes V; Le Roux I; Rhinn M; Schuhbaur B; Dolle P, Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways., Development 2009 Feb;136(4):665-76

J:151258, Kolterud A; Grosse AS; Zacharias WJ; Walton KD; Kretovich KE; Madison BB; Waghray M; Ferris JE; Hu C; Merchant JL; Dlugosz AA; Kottmann AH; Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning., Gastroenterology 2009 Aug;137(2):618-28

J:151923, Chen MH; Wilson CW; Li YJ; Law KK; Lu CS; Gacayan R; Zhang X; Hui CC; Chuang PT, Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved., Genes Dev 2009 Aug 15;23(16):1910-28

J:155992, Ching S; Vilain E, Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia., Genesis 2009 Sep;47(9):628-37

J:147584, Patterson VL; Damrau C; Paudyal A; Reeve B; Grimes DT; Stewart ME; Williams DJ; Siggers P; Greenfield A; Murdoch JN, Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway., Hum Mol Genet 2009 May 15;18(10):1719-39

J:147574, Norman RX; Ko HW; Huang V; Eun CM; Abler LL; Zhang Z; Sun X; Eggenschwiler JT, Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling., Hum Mol Genet 2009 May 15;18(10):1740-54

J:146198, Wall DS; Mears AJ; McNeill B; Mazerolle C; Thurig S; Wang Y; Kageyama R; Wallace VA, Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity., J Cell Biol 2009 Jan 12;184(1):101-12

J:153142, Clement CA; Kristensen SG; Mollgard K; Pazour GJ; Yoder BK; Larsen LA; Christensen ST, The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation., J Cell Sci 2009 Sep 1;122(Pt 17):3070-82

J:145723, Zhao M; Ko SY; Liu JH; Chen D; Zhang J; Wang B; Harris SE; Oyajobi BO; Mundy GR, Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2., Mol Cell Biol 2009 Mar;29(5):1291-305

J:150524, Chan JA; Balasubramanian S; Witt RM; Nazemi KJ; Choi Y; Pazyra-Murphy MF; Walsh CO; Thompson M; Segal RA, Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses., Nat Neurosci 2009 Apr;12(4):409-17

J:147759, Tan M; Davis SW; Saunders TL; Zhu Y; Sun Y, RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27., Proc Natl Acad Sci U S A 2009 Apr 14;106(15):6203-8

J:151965, Liem KF Jr; He M; Ocbina PJ; Anderson KV, Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling., Proc Natl Acad Sci U S A 2009 Aug 11;106(32):13377-82

J:150793, Zhou S; Degan S; Potts EN; Foster WM; Sunday ME, NPAS3 is a trachealess homolog critical for lung development and homeostasis., Proc Natl Acad Sci U S A 2009 Jul 14;106(28):11691-6

J:153743, Purcell P; Joo BW; Hu JK; Tran PV; Calicchio ML; O'Connell DJ; Maas RL; Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps., Proc Natl Acad Sci U S A 2009 Oct 27;106(43):18297-302

J:152259, Cheung HO; Zhang X; Ribeiro A; Mo R; Makino S; Puviindran V; Law KK; Briscoe J; Hui CC, The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling., Sci Signal 2009;2(76):ra29

J:139587, Gu LH; Coulombe PA, Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions., Am J Pathol 2008 Sep;173(3):752-61

J:136993, Sakai-Kato K; Ishiguro A; Mikoshiba K; Aruga J; Utsunomiya-Tate N, CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA., Biochim Biophys Acta 2008 Jul-Aug;1784(7-8):1011-9

J:135151, Sigulinsky CL; Green ES; Clark AM; Levine EM, Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina., Dev Biol 2008 May 15;317(2):560-75

J:138713, Cho A; Ko HW; Eggenschwiler JT, FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism., Dev Biol 2008 Sep 1;321(1):27-39

J:132152, Chamberlain CE; Jeong J; Guo C; Allen BL; McMahon AP, Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning., Development 2008 Mar;135(6):1097-106

J:143442, Sanchez-Camacho C; Bovolenta P, Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons., Development 2008 Nov;135(21):3531-41

J:143585, Yu W; McDonnell K; Taketo MM; Bai CB, Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner., Development 2008 Nov;135(22):3687-96

J:139508, Gao J; DeRouen MC; Chen CH; Nguyen M; Nguyen NT; Ido H; Harada K; Sekiguchi K; Morgan BA; Miner JH; Oro AE; Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis., Genes Dev 2008 Aug 1;22(15):2111-24

J:139256, Driver EC; Pryor SP; Hill P; Turner J; Ruther U; Biesecker LG; Griffith AJ; Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans., J Neurosci 2008 Jul 16;28(29):7350-8

J:141874, Cheng W; Yeung CK; Ng YK; Zhang JR; Hui CC; Kim PC, Sonic Hedgehog mediator Gli2 regulates bladder mesenchymal patterning., J Urol 2008;180(4):1543-50

J:144348, Ohazama A; Johnson EB; Ota MS; Choi HJ; Porntaveetus T; Oommen S; Itoh N; Eto K; Gritli-Linde A; Herz J; Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development., PLoS ONE 2008;3(12):e4092

J:139130, Breunig JJ; Sarkisian MR; Arellano JI; Morozov YM; Ayoub AE; Sojitra S; Wang B; Flavell RA; Rakic P; Town T, Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling., Proc Natl Acad Sci U S A 2008 Sep 2;105(35):13127-32

J:133905, Koyama E; Ochiai T; Rountree RB; Kingsley DM; Enomoto-Iwamoto M; Iwamoto M; Pacifici M, Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling., Ann N Y Acad Sci 2007 Nov;1116():100-12

J:119916, Yang HS; Hinds PW, pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development., BMC Dev Biol 2007;7():6

J:119875, Lebel M; Mo R; Shimamura K; Hui CC, Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain., Dev Biol 2007 Feb 1;302(1):345-55

J:119174, van Tuyl M; Groenman F; Wang J; Kuliszewski M; Liu J; Tibboel D; Post M, Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs., Dev Biol 2007 Mar 15;303(2):514-526

J:121301, Mau E; Whetstone H; Yu C; Hopyan S; Wunder JS; Alman BA, PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms., Dev Biol 2007 May 1;305(1):28-39

J:117334, Gritli-Linde A; Hallberg K; Harfe BD; Reyahi A; Kannius-Janson M; Nilsson J; Cobourne MT; Sharpe PT; McMahon AP; Linde A, Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling., Dev Cell 2007 Jan;12(1):99-112

J:117221, Shibukawa Y; Young B; Wu C; Yamada S; Long F; Pacifici M; Koyama E, Temporomandibular joint formation and condyle growth require Indian hedgehog signaling., Dev Dyn 2007 Feb;236(2):426-34

J:119913, Haraguchi R; Motoyama J; Sasaki H; Satoh Y; Miyagawa S; Nakagata N; Moon A; Yamada G, Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling., Development 2007 Feb;134(3):525-33

J:121232, Bok J; Dolson DK; Hill P; Ruther U; Epstein DJ; Wu DK, Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear., Development 2007 May;134(9):1713-22

J:127461, Shimoyama A; Wada M; Ikeda F; Hata K; Matsubara T; Nifuji A; Noda M; Amano K; Yamaguchi A; Nishimura R; Yoneda T, Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function., Mol Biol Cell 2007 Jul;18(7):2411-8

J:104803, Eggenschwiler JT; Bulgakov OV; Qin J; Li T; Anderson KV, Mouse Rab23 regulates Hedgehog signaling from Smoothened to Gli proteins., Dev Biol 2006 Feb 1;290(1):1-12

J:144902, Doles J; Cook C; Shi X; Valosky J; Lipinski R; Bushman W, Functional compensation in Hedgehog signaling during mouse prostate development., Dev Biol 2006 Jul 1;295(1):13-25

J:110699, Boras-Granic K; Chang H; Grosschedl R; Hamel PA, Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland., Dev Biol 2006 Jul 1;295(1):219-31

J:105832, Svard J; Henricson KH; Persson-Lek M; Rozell B; Lauth M; Bergstrom A; Ericson J; Toftgard R; Teglund S, Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway., Dev Cell 2006 Feb;10(2):187-97

J:112802, Lei Q; Jeong Y; Misra K; Li S; Zelman AK; Epstein DJ; Matise MP, Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube., Dev Cell 2006 Sep;11(3):325-37

J:106158, Furimsky M; Wallace VA, Complementary Gli activity mediates early patterning of the mouse visual system., Dev Dyn 2006 Mar;235(3):594-605

J:113421, Szczepny A; Hime GR; Loveland KL, Expression of hedgehog signalling components in adult mouse testis., Dev Dyn 2006 Nov;235(11):3063-70

J:104380, Hu MC; Mo R; Bhella S; Wilson CW; Chuang PT; Hui CC; Rosenblum ND, GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis., Development 2006 Feb;133(3):569-78

J:108509, Blaess S; Corrales JD; Joyner AL, Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region., Development 2006 May;133(9):1799-809

J:108507, Corrales JD; Blaess S; Mahoney EM; Joyner AL, The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation., Development 2006 May;133(9):1811-21

J:112460, Hatsell SJ; Cowin P, Gli3-mediated repression of Hedgehog targets is required for normal mammary development., Development 2006 Sep;133(18):3661-70

J:111617, Que J; Choi M; Ziel JW; Klingensmith J; Hogan BL, Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps., Differentiation 2006 Sep;74(7):422-37

J:111380, Lipinski RJ; Gipp JJ; Zhang J; Doles JD; Bushman W, Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling., Exp Cell Res 2006 Jul 1;312(11):1925-38

J:104154, Rice R; Connor E; Rice DP, Expression patterns of Hedgehog signalling pathway members during mouse palate development., Gene Expr Patterns 2006 Jan;6(2):206-12

J:111401, Zhao M; Qiao M; Harris SE; Chen D; Oyajobi BO; Mundy GR, The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling., Mol Cell Biol 2006 Aug;26(16):6197-208

J:108433, Pan Y; Bai CB; Joyner AL; Wang B, Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation., Mol Cell Biol 2006 May;26(9):3365-77

J:106707, Lien WH; Klezovitch O; Fernandez TE; Delrow J; Vasioukhin V, alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway., Science 2006 Mar 17;311(5767):1609-12

J:100687, Mill P; Mo R; Hu MC; Dagnino L; Rosenblum ND; Hui CC, Shh controls epithelial proliferation via independent pathways that converge on N-Myc., Dev Cell 2005 Aug;9(2):293-303

J:102853, Kim JH; Huang Z; Mo R, Gli3 null mice display glandular overgrowth of the developing stomach., Dev Dyn 2005 Dec;234(4):984-91

J:95234, Saitsu H; Komada M; Suzuki M; Nakayama R; Motoyama J; Shiota K; Ishibashi M, Expression of the mouse Fgf15 gene is directly initiated by Sonic hedgehog signaling in the diencephalon and midbrain., Dev Dyn 2005 Feb;232(2):282-92

J:110088, Taniwaki T; Haruna K; Nakamura H; Sekimoto T; Oike Y; Imaizumi T; Saito F; Muta M; Soejima Y; Utoh A; Nakagata N; Araki M; Yamamura K; Araki K, Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette., Dev Growth Differ 2005 Apr;47(3):163-72

J:102948, Koziel L; Wuelling M; Schneider S; Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation., Development 2005 Dec;132(23):5249-60

J:96926, Pan L; Yang Z; Feng L; Gan L, Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis., Development 2005 Feb;132(4):703-12

J:95326, McDermott A; Gustafsson M; Elsam T; Hui CC; Emerson CP Jr; Borycki AG, Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation., Development 2005 Jan;132(2):345-57

J:97242, Zhang XQ; Afink GB; Hu XR; Nister M; Forsberg-Nilsson K, Gli1 is not required for Pdgfralpha expression during mouse embryonic development., Differentiation 2005 Mar;73(2-3):109-19

J:103171, Barnfield PC; Zhang X; Thanabalasingham V; Yoshida M; Hui CC, Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms., Differentiation 2005 Oct;73(8):397-405

J:97323, Niedermaier M; Schwabe GC; Fees S; Helmrich A; Brieske N; Seemann P; Hecht J; Seitz V; Stricker S; Leschik G; Schrock E; Selby PB; Mundlos S, An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression., J Clin Invest 2005 Apr 1;115(4):900-909

J:112545, Wang XP; Aberg T; James MJ; Levanon D; Groner Y; Thesleff I, Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth., J Dent Res 2005 Feb;84(2):138-43

J:102358, Dillon AK; Fujita SC; Matise MP; Jarjour AA; Kennedy TE; Kollmus H; Arnold HH; Weiner JA; Sanes JR; Kaprielian Z, Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord., J Neurosci 2005 Nov 2;25(44):10119-30

J:126097, Cobellis G; Nicolaus G; Iovino M; Romito A; Marra E; Barbarisi M; Sardiello M; Di Giorgio FP; Iovino N; Zollo M; Ballabio A; Cortese R, Tagging genes with cassette-exchange sites., Nucleic Acids Res 2005;33(4):e44

J:115756, Haycraft CJ; Banizs B; Aydin-Son Y; Zhang Q; Michaud EJ; Yoder BK, Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function., PLoS Genet 2005 Oct;1(4):e53

J:92507, Ahn S; Joyner AL, Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning., Cell 2004 Aug 20;118(4):505-16

J:87948, Bai CB; Stephen D; Joyner AL, All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3., Dev Cell 2004 Jan;6(1):103-15

J:92067, Lei Q; Zelman AK; Kuang E; Li S; Matise MP, Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord., Development 2004 Aug;131(15):3593-604

J:90384, Palma V; Ruiz i Altaba A, Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex., Development 2004 Jan;131(2):337-45

J:88577, Mu X; Beremand PD; Zhao S; Pershad R; Sun H; Scarpa A; Liang S; Thomas TL; Klein WH, Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina., Development 2004 Mar;131(6):1197-210

J:94461, Corrales JD; Rocco GL; Blaess S; Guo Q; Joyner AL, Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development., Development 2004 Nov;131(22):5581-90

J:88344, Miao D; Liu H; Plut P; Niu M; Huo R; Goltzman D; Henderson JE, Impaired endochondral bone development and osteopenia in Gli2-deficient mice., Exp Cell Res 2004 Mar 10;294(1):210-22

J:91257, Gray PA; Fu H; Luo P; Zhao Q; Yu J; Ferrari A; Tenzen T; Yuk DI; Tsung EF; Cai Z; Alberta JA; Cheng LP; Liu Y; Stenman JM; Valerius MT; Billings N; Kim HA; Greenberg ME; McMahon AP; Rowitch DH; Stiles CD; Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis., Science 2004 Dec 24;306(5705):2255-2257

J:86613, Allen M; Grachtchouk M; Sheng H; Grachtchouk V; Wang A; Wei L; Liu J; Ramirez A; Metzger D; Chambon P; Jorcano J; Dlugosz AA, Hedgehog signaling regulates sebaceous gland development., Am J Pathol 2003 Dec;163(6):2173-8

J:82736, Charron F; Stein E; Jeong J; McMahon AP; Tessier-Lavigne M, The Morphogen Sonic Hedgehog Is an Axonal Chemoattractant that Collaborates with Netrin-1 in Midline Axon Guidance., Cell 2003 Apr 4;113(1):11-23

J:84056, Motoyama J; Milenkovic L; Iwama M; Shikata Y; Scott MP; Hui CC, Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification., Dev Biol 2003 Jul 1;259(1):150-61

J:87223, Buttitta L; Mo R; Hui CC; Fan CM, Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction., Development 2003 Dec;130(25):6233-43

J:103092, Line SR, Variation of tooth number in mammalian dentition: connecting genetics, development, and evolution., Evol Dev 2003 May-Jun;5(3):295-304

J:81295, Mill P; Mo R; Fu H; Grachtchouk M; Kim PC; Dlugosz AA; Hui CC, Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development., Genes Dev 2003 Jan 15;17(2):282-94

J:84432, Qi Y; Tan M; Hui CC; Qiu M, Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord., Mol Cell Neurosci 2003 Jul;23(3):440-50

J:91812, Stryke D; Kawamoto M; Huang CC; Johns SJ; King LA; Harper CA; Meng EC; Lee RE; Yee A; L'Italien L; Chuang PT; Young SG; Skarnes WC; Babbitt PC; Ferrin TE, BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic Acids Res 2003 Jan 1;31(1):278-81

J:85162, Hansen J; Floss T; Van Sloun P; Fuchtbauer EM; Vauti F; Arnold HH; Schnutgen F; Wurst W; von Melchner H; Ruiz P, A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome., Proc Natl Acad Sci U S A 2003 Aug 19;100(17):9918-22

J:86696, Zambrowicz BP; Abuin A; Ramirez-Solis R; Richter LJ; Piggott J; BeltrandelRio H; Buxton EC; Edwards J; Finch RA; Friddle CJ; Gupta A; Hansen G; Hu Y; Huang W; Jaing C; Key BW Jr; Kipp P; Kohlhauff B; Ma ZQ; Markesich D; Payne R; Potter DG; Qian N; Shaw J; Schrick J; Shi ZZ; Sparks MJ; Van Sligtenhorst I; Vogel P; Walke W; Xu N; Zhu Q; Person C; Sands AT, Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention., Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14109-14

J:76411, Lim L; Kalinichenko VV; Whitsett JA; Costa RH, Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele., Am J Physiol Lung Cell Mol Physiol 2002 May;282(5):L1012-22

J:74270, Chen J; Harrison DE, Quantitative trait loci regulating relative lymphocyte proportions in mouse peripheral blood., Blood 2002 Jan 15;99(2):561-6

J:78407, O'Rourke MP; Soo K; Behringer RR; Hui CC; Tam PP, Twist plays an essential role in FGF and SHH signal transduction during mouse limb development., Dev Biol 2002 Aug 1;248(1):143-56

J:77264, Nguyen NM; Miner JH; Pierce RA; Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung., Dev Biol 2002 Jun 15;246(2):231-44

J:78990, Lamm ML; Catbagan WS; Laciak RJ; Barnett DH; Hebner CM; Gaffield W; Walterhouse D; Iannaccone P; Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation., Dev Biol 2002 Sep 15;249(2):349-66

J:80081, Gritli-Linde A; Bei M; Maas R; Zhang XM; Linde A; McMahon AP, Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization., Development 2002 Dec;129(23):5323-37

J:79392, Bai CB; Auerbach W; Lee JS; Stephen D; Joyner AL, Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway., Development 2002 Oct;129(20):4753-61

J:76394, Koebernick K; Pieler T, Gli-type zinc finger proteins as bipotential transducers of Hedgehog signaling., Differentiation 2002 May;70(2-3):69-76

J:80052, Nakashima M; Tanese N; Ito M; Auerbach W; Bai C; Furukawa T; Toyono T; Akamine A; Joyner AL, A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development., Mech Dev 2002 Nov;119(1):21

J:80000, The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs, Nature 2002;420():563-573

J:70870, Mo R; Kim JH; Zhang J; Chiang C; Hui CC; Kim PC, Anorectal malformations caused by defects in sonic hedgehog signaling., Am J Pathol 2001 Aug;159(2):765-74

J:69771, Lewis PM; Dunn MP; McMahon JA; Logan M; Martin JF; St-Jacques B; McMahon AP, Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1., Cell 2001 Jun 1;105(5):599-612

J:72024, Lewis MT; Ross S; Strickland PA; Sugnet CW; Jimenez E; Hui Cc CC; Daniel CW, The gli2 transcription factor is required for normal mouse mammary gland development., Dev Biol 2001 Oct 1;238(1):133-44

J:73074, Bai CB; Joyner AL, Gli1 can rescue the in vivo function of Gli2., Development 2001 Dec;128(24):5161-72

J:73075, Dahmane N; Sanchez P; Gitton Y; Palma V; Sun T; Beyna M; Weiner H; Ruiz i Altaba A, The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis., Development 2001 Dec;128(24):5201-12

J:72303, Haraguchi R; Mo R; Hui C; Motoyama J; Makino S; Shiroishi T; Gaffield W; Yamada G, Unique functions of Sonic hedgehog signaling during external genitalia development., Development 2001 Nov;128(21):4241-50

J:114033, Koyabu Y; Nakata K; Mizugishi K; Aruga J; Mikoshiba K, Physical and functional interactions between Zic and Gli proteins., J Biol Chem 2001 Mar 9;276(10):6889-92

J:113186, Kim PC; Mo R; Hui Cc C, Murine models of VACTERL syndrome: Role of sonic hedgehog signaling pathway., J Pediatr Surg 2001 Feb;36(2):381-4

J:70831, Becker MB; Zulch A; Bosse A; Gruss P, Irx1 and Irx2 expression in early lung development., Mech Dev 2001 Aug;106(1-2):155-8

J:70832, Zulch A; Becker MB; Gruss P, Expression pattern of Irx1 and Irx2 during mouse digit development., Mech Dev 2001 Aug;106(1-2):159-62

J:66532, Hecksher-Sorensen J; Sharpe J, 3D confocal reconstruction of gene expression in mouse., Mech Dev 2001 Jan;100(1):59-63

J:60986, Park HL; Bai C; Platt KA; Matise MP; Beeghly A; Hui CC; Nakashima M; Joyner AL, Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation., Development 2000 Apr;127(8):1593-605

J:59288, Baur ST; Mai JJ; Dymecki SM, Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity., Development 2000 Feb;127(3):605-19

J:64678, Epstein DJ; Martinu L; Michaud JL; Losos KM; Fan C; Joyner AL, Members of the bHLH-PAS family regulate shh transcription in forebrain regions of the mouse CNS, Development 2000 Nov;127(21):4701-9

J:65294, Dassule HR; Lewis P; Bei M; Maas R; McMahon AP, Sonic hedgehog regulates growth and morphogenesis of the tooth, Development 2000 Nov;127(22):4775-85

J:62920, Grimmond S; Hateren NV; Siggers P; Arkell R; Larder R; Soares MB; Bonaldo Md; Smith L; Tymowska-Lalanne Z; Wells C; Greenfield A, Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development, Hum Mol Genet 2000 Jun 12;9(10):1553-60

J:64180, Outram SV; Varas A; Pepicelli CV; Crompton T, Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte., Immunity 2000 Aug;13(2):187-97

J:60446, Kimmel SG; Mo R; Hui CC; Kim PC, New mouse models of congenital anorectal malformations, J Pediatr Surg 2000 Feb;35(2):227-31

J:65651, Neidhardt L; Gasca S; Wertz K; Obermayr F; Worpenberg S; Lehrach H; Herrmann BG, Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos, Mech Dev 2000 Nov;98(1-2):77-94

J:113893, Murone M; Luoh SM; Stone D; Li W; Gurney A; Armanini M; Grey C; Rosenthal A; de Sauvage FJ, Gli regulation by the opposing activities of fused and suppressor of fused., Nat Cell Biol 2000 May;2(5):310-2

J:60757, Grachtchouk M; Mo R; Yu S; Zhang X; Sasaki H; Hui CC; Dlugosz AA, Basal cell carcinomas in mice overexpressing Gli2 in skin., Nat Genet 2000 Mar;24(3):216-7

J:54985, Warburton D; Zhao J; Berberich MA; Bernfield M, Molecular embryology of the lung: then, now, and in the future., Am J Physiol 1999 May;276(5 Pt 1):L697-704

J:52981, Hogan BL, Morphogenesis., Cell 1999 Jan 22;96(2):225-33

J:60109, Hardcastle Z; Hui CC; Sharpe PT, The Shh signalling pathway in early tooth development., Cell Mol Biol (Noisy-le-grand) 1999 Jul;45(5):567-78

J:93290, Araki K; Imaizumi T; Sekimoto T; Yoshinobu K; Yoshimuta J; Akizuki M; Miura K; Araki M; Yamamura K, Exchangeable gene trap using the Cre/mutated lox system., Cell Mol Biol (Noisy-le-grand) 1999 Jul;45(5):737-50

J:54746, Matise MP; Lustig M; Sakurai T; Grumet M; Joyner AL, Ventral midline cells are required for the local control of commissural axon guidance in the mouse spinal cord., Development 1999 Aug;126(16):3649-59

J:55583, Tribioli C; Lufkin T, The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen., Development 1999 Dec;126(24):5699-711

J:20187, Dahmane N; Ruiz-i-Altaba A, Sonic hedgehog regulates the growth and patterning of the cerebellum., Development 1999 Jun;126(14):3089-100

J:42408, Lewis MT; Ross S; Strickland PA; Sugnet CW; Jimenez E; Scott MP; Daniel CW, Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1., Development 1999 Nov;126(22):5181-93

J:58673, Heymer J; Ruther U, Syndactyly of Ft/+ mice correlates with an imbalance in bmp4 and fgf8 expression., Mech Dev 1999 Nov;88(2):173-81

J:52548, Wechsler-Reya RJ; Scott MP, Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog [see comments], Neuron 1999 Jan;22(1):103-14

J:53098, Peters H; Balling R, Teeth. Where and how to make them., Trends Genet 1999 Feb;15(2):59-65

J:50050, St-Jacques B; Dassule HR; Karavanova I; Botchkarev VA; Li J; Danielian PS; McMahon JA; Lewis PM; Paus R; McMahon AP, Sonic hedgehog signaling is essential for hair development., Curr Biol 1998 Sep 24;8(19):1058-68

J:50051, Pepicelli CV; Lewis PM; McMahon AP, Sonic hedgehog regulates branching morphogenesis in the mammalian lung., Curr Biol 1998 Sep 24;8(19):1083-6

J:45211, Buscher D; Ruther U, Expression profile of Gli family members and Shh in normal and mutant mouse limb development., Dev Dyn 1998 Jan;211(1):88-96

J:49251, Matise MP; Epstein DJ; Park HL; Platt KA; Joyner AL, Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system., Development 1998 Aug;125(15):2759-70

J:49252, Hardcastle Z; Mo R; Hui CC; Sharpe PT, The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants., Development 1998 Aug;125(15):2803-11

J:49653, Yang Y; Guillot P; Boyd Y; Lyon MF; McMahon AP, Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling., Development 1998 Aug;125(16):3123-32

J:49164, Ding Q; Motoyama J; Gasca S; Mo R; Sasaki H; Rossant J; Hui CC, Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice., Development 1998 Jul;125(14):2533-43

J:49603, Motoyama J; Liu J; Mo R; Ding Q; Post M; Hui CC, Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus [see comments], Nat Genet 1998 Sep;20(1):54-7

J:42454, Grindley JC; Bellusci S; Perkins D; Hogan BL, Evidence for the involvement of the Gli gene family in embryonic mouse lung development., Dev Biol 1997 Aug 15;188(2):337-48

J:40390, Sasaki H; Hui C; Nakafuku M; Kondoh H, A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro., Development 1997 Apr;124(7):1313-22

J:38381, Mo R; Freer AM; Zinyk DL; Crackower MA; Michaud J; Heng HH; Chik KW; Shi XM; Tsui LC; Cheng SH; Joyner AL; Hui C, Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development., Development 1997 Jan;124(1):113-23

J:41684, Lee J; Platt KA; Censullo P; Ruiz i Altaba A, Gli1 is a target of Sonic hedgehog that induces ventral neural tube development., Development 1997 Jul;124(13):2537-52

J:38297, Hughes DC; Allen J; Morley G; Sutherland K; Ahmed W; Prosser J; Lettice L; Allan G; Mattei MG; Farrall M; Hill RE, Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region., Genomics 1997 Jan 15;39(2):205-15

J:39659, Platt KA; Michaud J; Joyner AL, Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice., Mech Dev 1997 Mar;62(2):121-35

J:41861, Hynes M; Stone DM; Dowd M; Pitts-Meek S; Goddard A; Gurney A ; Rosenthal A, Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1., Neuron 1997 Jul;19(1):15-26

J:40587, Persengiev SP; Kondova II; Millette CF; Kilpatrick DL, Gli family members are differentially expressed during the mitotic phase of spermatogenesis., Oncogene 1997 May 15;14(19):2259-64

J:30339, Millen KJ; Hui CC; Joyner AL, A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum., Development 1995 Dec;121(12):3935-45

J:17485, Hui CC; Slusarski D; Platt KA; Holmgren R; Joyner AL, Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development., Dev Biol 1994 Apr;162(2):402-13

J:4086, Hui CC; Joyner AL, A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene., Nat Genet 1993 Mar;3(3):241-6