J:156169, Cheng Y; Sudarov A; Szulc KU; Sgaier SK; Stephen D; Turnbull DH; Joyner AL, The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum., Development 2010 Feb;137(3):519-29
J:153963, Sato T; Joyner AL, The duration of Fgf8 isthmic organizer expression is key to patterning different tectal-isthmo-cerebellum structures., Development 2009 Nov;136(21):3617-26
J:151144, Moy SS; Nadler JJ; Young NB; Nonneman RJ; Grossman AW; Murphy DL; D'Ercole AJ; Crawley JN; Magnuson TR; Lauder JM, Social approach in genetically engineered mouse lines relevant to autism., Genes Brain Behav 2009 Mar;8(2):129-42
J:147446, Yamauchi K; Mizushima S; Tamada A; Yamamoto N; Takashima S; Murakami F, FGF8 signaling regulates growth of midbrain dopaminergic axons by inducing semaphorin 3F., J Neurosci 2009 Apr 1;29(13):4044-55
J:148961, Tripathi PP; Sgado P; Scali M; Viaggi C; Casarosa S; Simon HH; Vaglini F; Corsini GU; Bozzi Y, Increased susceptibility to kainic acid-induced seizures in Engrailed-2 knockout mice., Neuroscience 2009 Mar 17;159(2):842-9
J:143929, Robinson JF; Yu X; Hong S; Griffith WC; Beyer R; Kim E; Faustman EM, Cadmium-induced differential toxicogenomic response in resistant and sensitive mouse strains undergoing neurulation., Toxicol Sci 2009 Jan;107(1):206-19
J:142596, Hirano M; Hashimoto S; Yonemura S; Sabe H; Aizawa S, EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition., J Cell Biol 2008 Sep 22;182(6):1217-30
J:142371, Sillitoe RV; Stephen D; Lao Z; Joyner AL, Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum., J Neurosci 2008 Nov 19;28(47):12150-62
J:136110, Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals), MGI Direct Data Submission 2008;():
J:141773, Holst MI; Maercker C; Pintea B; Masseroli M; Liebig C; Jankowski J; Miething A; Martini J; Schwaller B; Oberdick J; Schilling K; Baader SL, Engrailed-2 regulates genes related to vesicle formation and transport in cerebellar Purkinje cells., Mol Cell Neurosci 2008 Aug;38(4):495-504
J:139698, Wataya T; Ando S; Muguruma K; Ikeda H; Watanabe K; Eiraku M; Kawada M; Takahashi J; Hashimoto N; Sasai Y, Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation., Proc Natl Acad Sci U S A 2008 Aug 19;105(33):11796-801
J:116544, Kuemerle B; Gulden F; Cherosky N; Williams E; Herrup K, The mouse Engrailed genes: A window into autism., Behav Brain Res 2007 Jan 10;176(1):121-32
J:130649, Fossat N; Le Greneur C; Beby F; Vincent S; Godement P; Chatelain G; Lamonerie T, A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors., BMC Dev Biol 2007;7():122
J:117489, Horn Z; Papachristou P; Shariatmadari M; Peyronnet J; Eriksson B; Ringstedt T, Wnt7a overexpression delays beta-tubulin III expression in transgenic mouse embryos., Brain Res 2007 Jan 26;1130(1):67-72
J:134435, Anselme I; Laclef C; Lanaud M; Ruther U; Schneider-Maunoury S, Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes., Dev Biol 2007 Apr 1;304(1):208-20
J:118803, Ribes V; Otto DM; Dickmann L; Schmidt K; Schuhbaur B; Henderson C; Blomhoff R; Wolf CR; Tickle C; Dolle P, Rescue of cytochrome P450 oxidoreductase (Por) mouse mutants reveals functions in vasculogenesis, brain and limb patterning linked to retinoic acid homeostasis., Dev Biol 2007 Mar 1;303(1):66-81
J:124187, Correia AC; Costa M; Moraes F; Bom J; Novoa A; Mallo M, Bmp2 is required for migration but not for induction of neural crest cells in the mouse., Dev Dyn 2007 Sep;236(9):2493-501
J:117035, Guo C; Qiu HY; Huang Y; Chen H; Yang RQ; Chen SD; Johnson RL; Chen ZF; Ding YQ, Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice., Development 2007 Jan;134(2):317-25
J:134516, Sgaier SK; Lao Z; Villanueva MP; Berenshteyn F; Stephen D; Turnbull RK; Joyner AL, Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins., Development 2007 Jun;134(12):2325-35
J:124270, Ono Y; Nakatani T; Sakamoto Y; Mizuhara E; Minaki Y; Kumai M; Hamaguchi A; Nishimura M; Inoue Y; Hayashi H; Takahashi J; Imai T, Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells., Development 2007 Sep;134(17):3213-25
J:114464, Cheh MA; Millonig JH; Roselli LM; Ming X; Jacobsen E; Kamdar S; Wagner GC, En2 knockout mice display neurobehavioral and neurochemical alterations relevant to autism spectrum disorder., Brain Res 2006 Oct 20;1116(1):166-76
J:108393, Chung AC; Xu X; Niederreither KA; Cooney AJ, Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer., Dev Biol 2006 May 1;293(1):13-24
J:108723, Andersson O; Reissmann E; Jornvall H; Ibanez CF, Synergistic interaction between Gdf1 and Nodal during anterior axis development., Dev Biol 2006 May 15;293(2):370-81
J:112633, Jukkola T; Lahti L; Naserke T; Wurst W; Partanen J, FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region., Dev Biol 2006 Sep 1;297(1):141-57
J:108519, Waters ST; Lewandoski M, A threshold requirement for Gbx2 levels in hindbrain development., Development 2006 May;133(10):1991-2000
J:119561, Hirata T; Nakazawa M; Muraoka O; Nakayama R; Suda Y; Hibi M, Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions., Development 2006 Oct;133(20):3993-4004
J:107825, Thompson LH; Andersson E; Jensen JB; Barraud P; Guillemot F; Parmar M; Bjorklund A, Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon., Exp Neurol 2006 Mar;198(1):183-98
J:115270, Sgado P; Alberi L; Gherbassi D; Galasso SL; Ramakers GM; Alavian KN; Smidt MP; Dyck RH; Simon HH, Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice., Proc Natl Acad Sci U S A 2006 Oct 10;103(41):15242-7
J:95765, Echevarria D; Martinez S; Marques S; Lucas-Teixeira V; Belo JA, Mkp3 is a negative feedback modulator of Fgf8 signaling in the mammalian isthmic organizer., Dev Biol 2005 Jan 1;277(1):114-28
J:95363, Ramos-Mejia V; Escalante-Alcalde D; Kunath T; Ramirez L; Gertsenstein M; Nagy A; Lomeli H, Phenotypic analyses of mouse embryos with ubiquitous expression of Oct4: effects on mid-hindbrain patterning and gene expression., Dev Dyn 2005 Jan;232(1):180-90
J:98485, Nishioka N; Nagano S; Nakayama R; Kiyonari H; Ijiri T; Taniguchi K; Shawlot W; Hayashizaki Y; Westphal H; Behringer RR; Matsuda Y; Sakoda S; Kondoh H; Sasaki H, Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex., Development 2005 Jun;132(11):2535-46
J:98482, Bouchard M; Grote D; Craven SE; Sun Q; Steinlein P; Busslinger M, Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region., Development 2005 Jun;132(11):2633-43
J:102949, Li C; Xu X; Nelson DK; Williams T; Kuehn MR; Deng CX, FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis., Development 2005 Nov;132(21):4755-64
J:98184, Juenger CH; Holst MI; Duffe K; Jankowski J; Baader SL, Tetraspanin-5 (Tm4sf9) mRNA expression parallels neuronal maturation in the cerebellum of normal and L7En-2 transgenic mice., J Comp Neurol 2005 Mar 14;483(3):318-28
J:98539, Kimura J; Suda Y; Kurokawa D; Hossain ZM; Nakamura M; Takahashi M; Hara A; Aizawa S, Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium., J Neurosci 2005 May 25;25(21):5097-108
J:95392, Simon HH; Scholz C; O'Leary DD, Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner., Mol Cell Neurosci 2005 Jan;28(1):96-105
J:95823, Sgaier SK; Millet S; Villanueva MP; Berenshteyn F; Song C; Joyner AL, Morphogenetic and cellular movements that shape the mouse cerebellum; insights from genetic fate mapping., Neuron 2005 Jan 6;45(1):27-40
J:126097, Cobellis G; Nicolaus G; Iovino M; Romito A; Marra E; Barbarisi M; Sardiello M; Di Giorgio FP; Iovino N; Zollo M; Ballabio A; Cortese R, Tagging genes with cassette-exchange sites., Nucleic Acids Res 2005;33(4):e44
J:99680, The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome, Science 2005;309(5740):1559-1563
J:94933, Simon HH; Thuret S; Alberi L, Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors., Cell Tissue Res 2004 Oct;318(1):53-61
J:98363, Alberi L; Sgado P; Simon HH, Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons., Development 2004 Jul;131(13):3229-36
J:88592, Smidt MP; Smits SM; Bouwmeester H; Hamers FP; van der Linden AJ; Hellemons AJ; Graw J; Burbach JP, Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3., Development 2004 Mar;131(5):1145-55
J:135878, Jankowski J; Holst MI; Liebig C; Oberdick J; Baader SL, Engrailed-2 negatively regulates the onset of perinatal Purkinje cell differentiation., J Comp Neurol 2004 Apr 19;472(1):87-99
J:147559, Thuret S; Alavian KN; Gassmann M; Lloyd CK; Smits SM; Smidt MP; Klein R; Dyck RH; Simon HH, The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta., J Neurochem 2004 Dec;91(6):1302-11
J:90898, Andrae J; Afink G; Zhang XQ; Wurst W; Nister M, Forced expression of platelet-derived growth factor B in the mouse cerebellar primordium changes cell migration during midline fusion and causes cerebellar ectopia., Mol Cell Neurosci 2004 Jun;26(2):308-21
J:91004, Panhuysen M; Vogt Weisenhorn DM; Blanquet V; Brodski C; Heinzmann U; Beisker W; Wurst W, Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region., Mol Cell Neurosci 2004 May;26(1):101-11
J:91257, Gray PA; Fu H; Luo P; Zhao Q; Yu J; Ferrari A; Tenzen T; Yuk DI; Tsung EF; Cai Z; Alberta JA; Cheng LP; Liu Y; Stenman JM; Valerius MT; Billings N; Kim HA; Greenberg ME; McMahon AP; Rowitch DH; Stiles CD; Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis., Science 2004 Dec 24;306(5705):2255-2257
J:81152, Mukhopadhyay M; Teufel A; Yamashita T; Agulnick AD; Chen L; Downs KM; Schindler A; Grinberg A; Huang SP; Dorward D; Westphal H, Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation., Development 2003 Feb;130(3):495-505
J:83004, Trokovic R; Trokovic N; Hernesniemi S; Pirvola U; Vogt Weisenhorn DM; Rossant J; McMahon AP; Wurst W; Partanen J, FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals., EMBO J 2003 Apr 15;22(8):1811-23
J:81797, Lagutin OV; Zhu CC; Kobayashi D; Topczewski J; Shimamura K; Puelles L; Russell HR; McKinnon PJ; Solnica-Krezel L; Oliver G, Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development., Genes Dev 2003 Feb 1;17(3):368-79
J:84363, Bilovocky NA; Romito-DiGiacomo RR; Murcia CL; Maricich SM; Herrup K, Factors in the genetic background suppress the engrailed-1 cerebellar phenotype., J Neurosci 2003 Jun 15;23(12):5105-12
J:91812, Stryke D; Kawamoto M; Huang CC; Johns SJ; King LA; Harper CA; Meng EC; Lee RE; Yee A; L'Italien L; Chuang PT; Young SG; Skarnes WC; Babbitt PC; Ferrin TE, BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic Acids Res 2003 Jan 1;31(1):278-81
J:85162, Hansen J; Floss T; Van Sloun P; Fuchtbauer EM; Vauti F; Arnold HH; Schnutgen F; Wurst W; von Melchner H; Ruiz P, A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome., Proc Natl Acad Sci U S A 2003 Aug 19;100(17):9918-22
J:86696, Zambrowicz BP; Abuin A; Ramirez-Solis R; Richter LJ; Piggott J; BeltrandelRio H; Buxton EC; Edwards J; Finch RA; Friddle CJ; Gupta A; Hansen G; Hu Y; Huang W; Jaing C; Key BW Jr; Kipp P; Kohlhauff B; Ma ZQ; Markesich D; Payne R; Potter DG; Qian N; Shaw J; Schrick J; Shi ZZ; Sparks MJ; Van Sligtenhorst I; Vogel P; Walke W; Xu N; Zhu Q; Person C; Sands AT, Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention., Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14109-14
J:86465, Inatani M; Irie F; Plump AS; Tessier-Lavigne M; Yamaguchi Y, Mammalian brain morphogenesis and midline axon guidance require heparan sulfate., Science 2003 Nov 7;302(5647):1044-6
J:78344, Mustonen T; Tummers M; Mikami T; Itoh N; Zhang N; Gridley T; Thesleff I, Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth., Dev Biol 2002 Aug 15;248(2):281-93
J:74631, Tian E; Kimura C; Takeda N; Aizawa S; Matsuo I, Otx2 is required to respond to signals from anterior neural ridge for forebrain specification., Dev Biol 2002 Feb 15;242(2):204-23
J:80178, Simon AM; McWhorter AR, Vascular Abnormalities in Mice Lacking the Endothelial Gap Junction Proteins connexin37 and connexin40., Dev Biol 2002 Nov 15;251(2):206-20
J:76367, Rathjen J; Haines BP; Hudson KM; Nesci A; Dunn S; Rathjen PD, Directed differentiation of pluripotent cells to neural lineages: homogeneous formation and differentiation of a neurectoderm population., Development 2002 Jun;129(11):2649-61
J:73494, Aruga J; Inoue T; Hoshino J; Mikoshiba K, Zic2 controls cerebellar development in cooperation with zic1., J Neurosci 2002 Jan 1;22(1):218-25
J:74490, Degenhardt K; Rentschler S; Fishman G; Sassoon DA, Cellular and cis-regulation of En-2 expression in the mandibular arch., Mech Dev 2002 Feb;111(1-2):125-36
J:75491, Roberts C; Sutherland HF; Farmer H; Kimber W; Halford S; Carey A; Brickman JM; Wynshaw-Boris A; Scambler PJ, Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality., Mol Cell Biol 2002 Apr;22(7):2318-28
J:76658, Gross MK; Dottori M; Goulding M, Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord., Neuron 2002 May 16;34(4):535-49
J:80667, Iratni R; Yan YT; Chen C; Ding J; Zhang Y; Price SM; Reinberg D; Shen MM, Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1., Science 2002 Dec 6;298(5600):1996-9
J:69637, Alavizadeh A; Kiernan AE; Nolan P; Lo C; Steel KP; Bucan M, The wheels mutation in the mouse causes vascular, hindbrain, and inner ear defects., Dev Biol 2001 Jun 1;234(1):244-60
J:67742, Degenhardt K; Sassoon DA, A role for Engrailed-2 in determination of skeletal muscle physiologic properties., Dev Biol 2001 Mar 1;231(1):175-89
J:71787, Mukhopadhyay M; Shtrom S; Rodriguez-Esteban C; Chen L; Tsukui T; Gomer L; Dorward DW; Glinka A; Grinberg A; Huang SP; Niehrs C; Belmonte JC; Westphal H, Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse., Dev Cell 2001 Sep;1(3):423-34
J:66592, Liu A; Joyner AL, EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region., Development 2001 Jan;128(2):181-91
J:70745, Suda Y; Hossain ZM; Kobayashi C; Hatano O; Yoshida M; Matsuo I; Aizawa S, Emx2 directs the development of diencephalon in cooperation with Otx2., Development 2001 Jul;128(13):2433-50
J:71074, Hirata H; Tomita K; Bessho Y; Kageyama R, Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain., EMBO J 2001 Aug 15;20(16):4454-66
J:67399, Abu-Abed S; Dolle P; Metzger D; Beckett B; Chambon P; Petkovich M, The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures., Genes Dev 2001 Jan 15;15(2):226-40
J:69594, Hoodless PA; Pye M; Chazaud C; Labbe E; Attisano L; Rossant J; Wrana JL, FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse., Genes Dev 2001 May 15;15(10):1257-71
J:68925, Simon HH; Saueressig H; Wurst W; Goulding MD; O'Leary DD, Fate of midbrain dopaminergic neurons controlled by the engrailed genes., J Neurosci 2001 May 1;21(9):3126-34
J:59301, Ben-Zur T; Feige E; Motro B; Wides R, The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles., Dev Biol 2000 Jan 1;217(1):107-20
J:62984, Kitajima S; Takagi A; Inoue T; Saga Y, MesP1 and MesP2 are essential for the development of cardiac mesoderm., Development 2000 Aug;127(15):3215-26
J:53473, Niederreither K; Vermot J; Schuhbaur B; Chambon P; Dolle P, Retinoic acid synthesis and hindbrain patterning in the mouse embryo., Development 2000 Jan;127(1):75-85
J:61429, Xu J; Liu Z; Ornitz DM, Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures., Development 2000 May;127(9):1833-43
J:63451, Schimenti JC; Libby BJ; Bergstrom RA; Wilson LA; Naf D; Tarantino LM; Alavizadeh A; Lengeling A; Bucan M, Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells, Genome Res 2000 Jul;10(7):1043-50
J:63394, Clark RM; Marker PC; Kingsley DM, A novel candidate gene for mouse and human preaxial polydactyly with altered expression in limbs of Hemimelic extra-toes mutant mice, Genomics 2000 Jul 1;67(1):19-27
J:62530, Tarantino LM; Feiner L; Alavizadeh A; Wiltshire T; Hurle B; Ornitz DM; Webber AL; Raper J; Lengeling A; Rowe LB; Bucan M, A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5., Genomics 2000 May 15;66(1):55-64
J:60433, Li Song D; Joyner AL, Two Pax2/5/8-binding sites in Engrailed2 are required for proper initiation of endogenous mid-hindbrain expression., Mech Dev 2000 Feb;90(2):155-65
J:59069, Klingensmith J; Ang SL; Bachiller D; Rossant J, Neural induction and patterning in the mouse in the absence of the node and its derivatives., Dev Biol 1999 Dec 15;216(2):535-49
J:57262, Song J; Oh SP; Schrewe H; Nomura M; Lei H; Okano M; Gridley T; Li E, The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice., Dev Biol 1999 Sep 1;213(1):157-69
J:53291, Hentges K; Thompson K; Peterson A, The flat-top gene is required for the expansion and regionalization of the telencephalic primordium., Development 1999 Apr;126(8):1601-9
J:58078, Liu A; Losos K; Joyner AL, FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate., Development 1999 Nov;126(21):4827-38
J:55817, Rhinn M; Dierich A; Le Meur M; Ang S, Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain., Development 1999 Oct;126(19):4295-304
J:58939, Wallen A; Zetterstrom RH; Solomin L; Arvidsson M; Olson L; Perlmann T, Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice., Exp Cell Res 1999 Dec 15;253(2):737-46
J:74853, Caetano AR; Shiue YL; Lyons LA; O'Brien SJ; Laughlin TF; Bowling AT; Murray JD, A comparative gene map of the horse (Equus caballus)., Genome Res 1999 Dec;9(12):1239-49
J:53282, Gemel J; Jacobsen C; MacArthur CA, Fibroblast growth factor-8 expression is regulated by intronic engrailed and Pbx1-binding sites., J Biol Chem 1999 Feb 26;274(9):6020-6
J:51994, Retaux S; Rogard M; Bach I; Failli V; Besson MJ, Lhx9: a novel LIM-homeodomain gene expressed in the developing forebrain., J Neurosci 1999 Jan 15;19(2):783-93
J:55154, Schwarz M; Alvarez-Bolado G; Dressler G; Urbanek P; Busslinger M; Gruss P, Pax2/5 and Pax6 subdivide the early neural tube into three domains., Mech Dev 1999 Apr;82(1-2):29-39
J:56411, Yamamoto M; Fujinuma M; Tanaka M; Drager UC; McCaffery P, Sagittal band expression of COUP-TF2 gene in the developing cerebellum., Mech Dev 1999 Jun;84(1-2):143-6
J:47966, McClive P; Pall G; Newton K; Lee M; Mullins J; Forrester L, Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector., Dev Dyn 1998 Jun;212(2):267-76
J:49657, Dufort D; Schwartz L; Harpal K; Rossant J, The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis., Development 1998 Aug;125(16):3015-25
J:46641, Rhinn M; Dierich A; Shawlot W; Behringer RR; Le Meur M; Ang SL, Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification., Development 1998 Mar;125(5):845-56
J:47899, Acampora D; Avantaggiato V; Tuorto F; Barone P; Reichert H; Finkelstein R; Simeone A, Murine Otx1 and Drosophila otd genes share conserved genetic functions required in invertebrate and vertebrate brain development., Development 1998 May;125(9):1691-702
J:50418, Fujita A; Horio Y; Copeland NG; Gilbert DJ; Jenkins NA; Kurachi Y, Assignment of mouse cardiac two-pore background K+ channel gene (Kcnk4) to the proximal region of mouse chromosome 5., Genomics 1998 Nov 15;54(1):183-4
J:46505, Baader SL; Sanlioglu S; Berrebi AS; Parker-Thornburg J; Oberdick J, Ectopic overexpression of engrailed-2 in cerebellar Purkinje cells causes restricted cell loss and retarded external germinal layer development at lobule junctions., J Neurosci 1998 Mar 1;18(5):1763-73
J:46439, Freeman TC; Dixon AK; Campbell EA; Tait TM; Richardson PJ; Rice KM; Maslen GL; Metcalfe AD; Streuli CH; Bentley DR, Expression Mapping of Mouse Genes, MGI Direct Data Submission 1998;():
J:50926, Hough RB; Lengeling A; Bedian V; Lo C; Bucan M, Rump white inversion in the mouse disrupts dipeptidyl aminopeptidase-like protein 6 and causes dysregulation of Kit expression., Proc Natl Acad Sci U S A 1998 Nov 10;95(23):13800-5
J:49977, Yu BD; Hanson RD; Hess JL; Horning SE; Korsmeyer SJ, MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis., Proc Natl Acad Sci U S A 1998 Sep 1;95(18):10632-6
J:44554, London B; Trudeau MC; Newton KP; Beyer AK; Copeland NG; Gilbert DJ; Jenkins NA; Satler CA; Robertson GA, Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current., Circ Res 1997 Nov;81(5):870-8
J:47774, Fowler KJ; Newson AJ; MacDonald AC; Kalitsis P; Lyu MS; Kozak CA ; Choo KH, Chromosomal localization of mouse Cenpa gene., Cytogenet Cell Genet 1997;79(3-4):298-301
J:38197, Sheng HZ; Bertuzzi S; Chiang C; Shawlot W; Taira M; Dawid I; Westphal H, Expression of murine Lhx5 suggests a role in specifying the forebrain., Dev Dyn 1997 Feb;208(2):266-77
J:42110, Wassarman KM; Lewandoski M; Campbell K; Joyner AL; Rubenstein JL ; Martinez S ; Martin GR, Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function., Development 1997 Aug;124(15):2923-34
J:45302, Erickson SL; O'Shea KS; Ghaboosi N; Loverro L; Frantz G; Bauer M; Lu LH; Moore MW, ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice., Development 1997 Dec;124(24):4999-5011
J:41809, Filosa S; RiveraPerez JA; Gomez AP; Gansmuller A; Sasaki H; Behringer RR; Ang SL, goosecoid and HNF-3 beta genetically interact to regulate neural tube patterning during mouse embryogenesis., Development 1997 JUL;124(14):2843-2854
J:39204, Lee SM; Danielian PS; Fritzsch B; McMahon AP, Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain., Development 1997 Mar;124(5):959-69
J:43763, Gavalas A; Davenne M; Lumsden A; Chambon P; Rijli FM, Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning., Development 1997 Oct;124(19):3693-702
J:43308, Acampora D; Avantaggiato V; Tuorto F; Simeone A, Genetic control of brain morphogenesis through Otx gene dosage requirement., Development 1997 Sep;124(18):3639-50
J:43466, Kuemerle B; Zanjani H; Joyner A; Herrup K, Pattern deformities and cell loss in Engrailed-2 mutant mice suggest two separate patterning events during cerebellar development., J Neurosci 1997 Oct 15;17(20):7881-9
J:39617, Allen J; Colleaux L; Davidson D; Graham E; Lee M; Hill R; Abbott C ; Gordon C, Expression and mapping of the mouse S7/Pmsc2 gene, homolog of an essential mitotic gene in yeast., Mamm Genome 1997 May;8(5):352-4
J:37599, Wightman PJ; Hayward BE; Bonthron DT, The genes encoding glucokinase regulatory protein and ketohexokinase co-localize to mouse chromosome 5., Mamm Genome 1997 Sep;8(9):700-1
J:45681, Suda Y; Matsuo I; Aizawa S, Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain, Mech Dev 1997 Dec;69(1-2):125-41
J:45075, Schwarz M; Alvarez-Bolado G; Urbanek P; Busslinger M; Gruss P, Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations., Proc Natl Acad Sci U S A 1997 Dec 23;94(26):14518-23
J:40910, Urbanek P; Fetka I; Meisler MH; Busslinger M, Cooperation of Pax2 and Pax5 in midbrain and cerebellum development., Proc Natl Acad Sci U S A 1997 May 27;94(11):5703-8
J:31921, Gerlai R; Millen KJ; Herrup K; Fabien K; Joyner AL; Roder J, Impaired motor learning performance in cerebellar En-2 mutant mice., Behav Neurosci 1996 Feb;110(1):126-33
J:36711, Vogel MW; Ji Z; Millen K; Joyner AL, The Engrailed-2 homeobox gene and patterning of spinocerebellar mossy fiber afferents., Brain Res Dev Brain Res 1996 Oct 23;96(1-2):210-8
J:32929, Avantaggiato V; Acampora D; Tuorto F; Simeone A, Retinoic acid induces stage-specific repatterning of the rostral central nervous system., Dev Biol 1996 May 1;175(2):347-57
J:31472, Song DL; Chalepakis G; Gruss P; Joyner AL, Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene., Development 1996 Feb;122(2):627-35
J:30828, Ang SL; Jin O; Rhinn M; Daigle N; Stevenson L; Rossant J, A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain., Development 1996 Jan;122(1):243-52
J:37068, Wang Y; Macke JP; Abella BS; Andreasson K; Worley P; Gilbert DJ; Copeland NG; Jenkins NA; Nathans J, A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled., J Biol Chem 1996 Feb 23;271(8):4468-76
J:35802, Chiang C; Litingtung Y; Lee E; Young KE; Corden JL; Westphal H; Beachy PA, Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function., Nature 1996 Oct 3;383(6599):407-13
J:35491, Danielian PS; McMahon AP, Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development., Nature 1996 Sep 26;383(6598):332-4
J:37242, Palmiter RD; Cole TB; Quaife CJ; Findley SD, ZnT-3, a putative transporter of zinc into synaptic vesicles., Proc Natl Acad Sci U S A 1996 Dec 10;93(25):14934-9
J:24365, Bucan M; Nagle DL; Hough RB; Chapman VM; Lo CW, Lethality of Rw/Rw mouse embryos during early postimplantation development., Dev Biol 1995 Apr;168(2):307-18
J:30339, Millen KJ; Hui CC; Joyner AL, A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum., Development 1995 Dec;121(12):3935-45
J:29276, Acampora D; Mazan S; Lallemand Y; Avantaggiato V; Maury M; Simeone A; Brulet P, Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation., Development 1995 Oct;121(10):3279-90
J:24349, Chen ZF; Behringer RR, twist is required in head mesenchyme for cranial neural tube morphogenesis., Genes Dev 1995 Mar 15;9(6):686-99
J:29682, Matsuo I; Kuratani S; Kimura C; Takeda N; Aizawa S, Mouse Otx2 functions in the formation and patterning of rostral head., Genes Dev 1995 Nov 1;9(21):2646-58
J:28413, Ohshima T; Nagle JW; Pant HC; Joshi JB; Kozak CA; Brady RO; Kulkarni AB, Molecular cloning and chromosomal mapping of the mouse cyclin-dependent kinase 5 gene., Genomics 1995 Aug 10;28(3):585-8
J:27750, Marigo V; Roberts DJ; Lee SM; Tsukurov O; Levi T; Gastier JM; Epstein DJ; Gilbert DJ; Copeland NG; Seidman CE; Jenkins NA; Seidman JG; McMahon AP; Tabin C., Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog., Genomics 1995 Jul 1;28(1):44-51
J:29267, Zeitlin S; Liu JP; Chapman DL; Papaioannou VE; Efstratiadis A, Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue., Nat Genet 1995 Oct;11(2):155-63
J:24115, Shawlot W; Behringer RR, Requirement for Lim1 in head-organizer function [see comments], Nature 1995 Mar 30;374(6521):425-30
J:27767, Hanks M; Wurst W; Anson-Cartwright L; Auerbach AB; Joyner AL, Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2 [see comments], Science 1995 Aug 4;269(5224):679-82
J:27770, Sadler TW; Liu ET; Augustine KA, Antisense targeting of engrailed-1 causes abnormal axis formation in mouse embryos., Teratology 1995 May;51(5):292-9
J:27769, Augustine KA; Liu ET; Sadler TW, Antisense inhibition of engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development., Teratology 1995 May;51(5):300-10
J:19895, Ang SL; Rossant J, HNF-3 beta is essential for node and notochord formation in mouse development., Cell 1994 Aug 26;78(4):561-74
J:16438, Sasaki H; Hogan BL, HNF-3 beta as a regulator of floor plate development., Cell 1994 Jan 14;76(1):103-15
J:19212, Wurst W; Auerbach AB; Joyner AL, Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum., Development 1994 Jul;120(7):2065-75
J:17203, Millen KJ; Wurst W; Herrup K; Joyner AL, Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants., Development 1994 Mar;120(3):695-706
J:18125, Salinas PC; Fletcher C; Copeland NG; Jenkins NA; Nusse R, Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells., Development 1994 May;120(5):1277-86
J:18585, Jenuth JP; Fung E; Snyder FF, Assignment of a gene that determines erythrocytic guanosine-5'-triphosphate concentration (Gtpc) to mouse chromosome 9., Genome 1994 Jun;37(3):399-404
J:16931, Ceci JD; Matsuda Y; Grubber JM; Jenkins NA; Copeland NG; Chapman VM, Interspecific backcrosses provide an important new tool for centromere mapping of mouse chromosomes., Genomics 1994 Feb;19(3):515-24
J:19414, Nasir J; Lin B; Bucan M; Koizumi T; Nadeau JH; Hayden MR, The murine homologues of the Huntington disease gene (Hdh) and the alpha-adducin gene (Add1) map to mouse chromosome 5 within a region of conserved synteny with human chromosome 4p16.3., Genomics 1994 Jul 1;22(1):198-201
J:22174, Montgomery JC; Guarnieri MH; Tartaglia KE; Flaherty LA, High-resolution genetic map and YAC contig around the mouse neurological locus reeler., Mamm Genome 1994 Dec;5(12):756-61
J:19185, Grosson CL; MacDonald ME; Duyao MP; Ambrose CM; Roffler-Tarlov S; Gusella JF, Synteny conservation of the Huntington's disease gene and surrounding loci on mouse Chromosome 5., Mamm Genome 1994 Jul;5(7):424-8
J:19181, Robert B; Montagutelli X; Houzelstein D; Ferland L; Cohen A; Buckingham M; Guenet JL, Msx1 is close but not allelic to either Hm or Hx on mouse chromosome 5., Mamm Genome 1994 Jul;5(7):446-9
J:18646, Stephenson DA; Lee KH; Nagle DL; Yen CH; Morrow A; Miller D; Chapman VM; Bucan M, Mouse rump-white mutation associated with an inversion of chromosome 5., Mamm Genome 1994 Jun;5(6):342-8
J:21534, Miao GG; Smeyne RJ; D'Arcangelo G; Copeland NG; Jenkins NA; Morgan JI; Curran T, Isolation of an allele of reeler by insertional mutagenesis., Proc Natl Acad Sci U S A 1994 Nov 8;91(23):11050-4
J:19405, Lee CC; Kozak CA; Yamada KM, Structure, genetic mapping, and expression of the mouse Hgf/scatter factor gene., Cell Adhes Commun 1993 Sep;1(2):101-11
J:4604, Logan C; Khoo WK; Cado D; Joyner AL, Two enhancer regions in the mouse En-2 locus direct expression to the mid/hindbrain region and mandibular myoblasts., Development 1993 Mar;117(3):905-16
J:11882, Ang SL; Rossant J, Anterior mesendoderm induces mouse Engrailed genes in explant cultures., Development 1993 May;118(1):139-49
J:4620, Wada K; Zimmerman KL; Adamson MC; Yokotani N; Wenthold RJ; Kozak CA, Genetic mapping of the mouse gene encoding dipeptidyl aminopeptidase-like proteins., Mamm Genome 1993;4(4):234-7
J:12770, Frohman MA; Dickinson ME; Hogan BLM; Martin GR, Mapping of Gbx-1 to mouse Chromosome 5 and Gbx-2 to mouse Chromosome 1, Mouse Genome 1993 June;91(2):323-25
J:4243, Kessel M, Reversal of axonal pathways from rhombomere 3 correlates with extra Hox expression domains., Neuron 1993 Mar;10(3):379-93
J:971, McMahon AP; Joyner AL; Bradley A; McMahon JA, The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum., Cell 1992 May 15;69(4):581-95
J:1520, Yamaguchi TP; Conlon RA; Rossant J, Expression of the fibroblast growth factor receptor FGFR-1/flg during gastrulation and segmentation in the mouse embryo., Dev Biol 1992 Jul;152(1):75-88
J:17915, Logan C; Hanks MC; Noble-Topham S; Nallainathan D; Provart NJ; Joyner AL, Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions., Dev Genet 1992;13(5):345-58
J:2140, Bally-Cuif L; Alvarado-Mallart RM; Darnell DK; Wassef M, Relationship between Wnt-1 and En-2 expression domains during early development of normal and ectopic met-mesencephalon., Development 1992 Aug;115(4):999-1009
J:3685, Shimamura K; Takeichi M, Local and transient expression of E-cadherin involved in mouse embryonic brain morphogenesis., Development 1992 Dec;116(4):1011-9
J:3101, Conlon RA; Rossant J, Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo., Development 1992 Oct;116(2):357-68
J:1525, Goffinet AM, The reeler gene: a clue to brain development and evolution., Int J Dev Biol 1992 Mar;36(1):101-7
J:1064, Wilkie TM; Gilbert DJ; Olsen AS; Chen XN; Amatruda TT; Korenberg JR; Trask BJ; de Jong P; Reed RR; Simon MI; Jenkins NA; Copeland NG, Evolution of the mammalian G protein alpha subunit multigene family., Nat Genet 1992 May;1(2):85-91
J:1682, Dumont DJ; Yamaguchi TP; Conlon RA; Rossant J; Breitman ML, tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors., Oncogene 1992 Aug;7(8):1471-80
J:31181, Davis CA; Holmyard DP; Millen KJ; Joyner AL, Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum., Development 1991 Feb;111(2):287-98
J:2349, Dernoncourt C; Ruelle D; Goffinet AM, Estimation of genetic distances between reeler and nearby loci on mouse chromosome 5., Genomics 1991 Dec;11(4):1167-9
J:562, Goffinet AM; Dernoncourt C, Localization of the reeler gene relative to flanking loci on mouse chromosome 5., Mamm Genome 1991;1(2):100-3
J:1775, Singh G; Kaur S; Stock JL; Jenkins NA; Gilbert DJ; Copeland NG; Potter SS, Identification of 10 murine homeobox genes., Proc Natl Acad Sci U S A 1991 Dec 1;88(23):10706-10
J:67524, Joyner AL; Herrup K; Auerbach BA; Davis CA; Rossant J, Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox., Science 1991 Mar 8;251(4998):1239-43
J:10929, Holland PW; Williams NA, Conservation of engrailed-like homeobox sequences during vertebrate evolution., FEBS Lett 1990 Dec 17;277(1-2):250-2
J:10340, Martin GR; Richman M; Reinsch S; Nadeau JH; Joyner A, Mapping of the two mouse engrailed-like genes: close linkage of En-1 to dominant hemimelia (Dh) on chromosome 1 and of En-2 to hemimelic extra-toes (Hx) on chromosome 5., Genomics 1990 Feb;6(2):302-8
J:9723, Hill RE; Jones PF; Rees AR; Sime CM; Justice MJ; Copeland NG; Jenkins NA; Graham E; Davidson DR, A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1., Genes Dev 1989 Jan;3(1):26-37
J:9752, Poole SJ; Law ML; Kao FT; Lau YF, Isolation and chromosomal localization of the human En-2 gene., Genomics 1989 Apr;4(3):225-31
J:9598, Mock BA; Nordan RP; Justice MJ; Kozak C; Jenkins NA; Copeland NG; Clark SC; Wong GG; Rudikoff S, The murine Il-6 gene maps to the proximal region of chromosome 5., J Immunol 1989 Feb 15;142(4):1372-6
J:9141, Johnson PA; Peschon JJ; Yelick PC; Palmiter RD; Hecht NB, Sequence homologies in the mouse protamine 1 and 2 genes., Biochim Biophys Acta 1988 May 6;950(1):45-53
J:9911, Davidson D; Graham E; Sime C; Hill R, A gene with sequence similarity to Drosophila engrailed is expressed during the development of the neural tube and vertebrae in the mouse., Development 1988 Oct;104(2):305-16
J:31313, Davis CA; Joyner AL, Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development., Genes Dev 1988 Dec;2(12B):1736-44
J:31312, Davis CA; Noble-Topham SE; Rossant J; Joyner AL, Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain., Genes Dev 1988 Mar;2(3):361-71
J:9012, Joyner AL; Martin GR, En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis [published erratum appears in Genes Dev 1987 Jul;1(5):521], Genes Dev 1987 Mar;1(1):29-38
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