537 matching items displayed in reverse chronological order

J:147382, Genethliou N; Panayiotou E; Panayi H; Orford M; Mean R; Lapathitis G; Malas S, Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord., Biochem Biophys Res Commun 2009 Apr 24;382(1):69-73

J:144571, Perry JM; Harandi OF; Porayette P; Hegde S; Kannan AK; Paulson RF, Maintenance of the BMP4-dependent stress erythropoiesis pathway in the murine spleen requires hedgehog signaling., Blood 2009 Jan 22;113(4):911-8

J:151338, Siggins SL; Nguyen NY; McCormack MP; Vasudevan S; Villani R; Jane SM; Wainwright BJ; Curtis DJ, The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms., Blood 2009 Jul 30;114(5):995-1004

J:144811, Read TA; Fogarty MP; Markant SL; McLendon RE; Wei Z; Ellison DW; Febbo PG; Wechsler-Reya RJ, Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma., Cancer Cell 2009 Feb 3;15(2):135-47

J:144974, Ecke I; Petry F; Rosenberger A; Tauber S; Monkemeyer S; Hess I; Dullin C; Kimmina S; Pirngruber J; Johnsen SA; Uhmann A; Nitzki F; Wojnowski L; Schulz-Schaeffer W; Witt O; Hahn H, Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice., Cancer Res 2009 Feb 1;69(3):887-95

J:149309, Ward RJ; Lee L; Graham K; Satkunendran T; Yoshikawa K; Ling E; Harper L; Austin R; Nieuwenhuis E; Clarke ID; Hui CC; Dirks PB, Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma., Cancer Res 2009 Jun 1;69(11):4682-90

J:144867, Mancuso M; Gallo D; Leonardi S; Pierdomenico M; Pasquali E; De Stefano I; Rebessi S; Tanori M; Scambia G; Di Majo V; Covelli V; Pazzaglia S; Saran A, Modulation of basal and squamous cell carcinoma by endogenous estrogen in mouse models of skin cancer., Carcinogenesis 2009 Feb;30(2):340-7

J:149148, Zibat A; Uhmann A; Nitzki F; Wijgerde M; Frommhold A; Heller T; Armstrong V; Wojnowski L; Quintanilla-Martinez L; Reifenberger J; Schulz-Schaeffer W; Hahn H, Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts., Carcinogenesis 2009 Jun;30(6):918-26

J:152551, Endoh-Yamagami S; Evangelista M; Wilson D; Wen X; Theunissen JW; Phamluong K; Davis M; Scales SJ; Solloway MJ; de Sauvage FJ; Peterson AS, The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development., Curr Biol 2009 Aug 11;19(15):1320-6

J:155112, Tsiairis CD; McMahon AP, An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry., Curr Biol 2009 Dec 1;19(22):1912-7

J:149459, Wuelling M; Kaiser FJ; Buelens LA; Braunholz D; Shivdasani RA; Depping R; Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3., Dev Biol 2009 Apr 1;328(1):40-53

J:143544, Cortellino S; Wang C; Wang B; Bassi MR; Caretti E; Champeval D; Calmont A; Jarnik M; Burch J; Zaret KS; Larue L; Bellacosa A, Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4., Dev Biol 2009 Jan 1;325(1):225-37

J:150375, Cobourne MT; Xavier GM; Depew M; Hagan L; Sealby J; Webster Z; Sharpe PT, Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome., Dev Biol 2009 Jul 1;331(1):38-49

J:150755, Oh S; Huang X; Liu J; Litingtung Y; Chiang C, Shh and Gli3 activities are required for timely generation of motor neuron progenitors., Dev Biol 2009 Jul 15;331(2):261-9

J:149232, Xiong W; He F; Morikawa Y; Yu X; Zhang Z; Lan Y; Jiang R; Cserjesi P; Chen Y, Hand2 is required in the epithelium for palatogenesis in mice., Dev Biol 2009 Jun 1;330(1):131-41

J:145732, Aoto K; Shikata Y; Imai H; Matsumaru D; Tokunaga T; Shioda S; Yamada G; Motoyama J, Mouse Shh is required for prechordal plate maintenance during brain and craniofacial morphogenesis., Dev Biol 2009 Mar 1;327(1):106-20

J:146434, Maatouk DM; Choi KS; Bouldin CM; Harfe BD, In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth., Dev Biol 2009 Mar 15;327(2):516-23

J:154376, Stottmann RW; Tran PV; Turbe-Doan A; Beier DR, Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain., Dev Biol 2009 Nov 1;335(1):166-78

J:154375, Ng A; Wong M; Viviano B; Erlich JM; Alba G; Pflederer C; Jay PY; Saunders S, Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development., Dev Biol 2009 Nov 1;335(1):208-15

J:152420, Denaxa M; Sharpe PT; Pachnis V, The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition., Dev Biol 2009 Sep 15;333(2):324-36

J:149477, Zhang Z; Verheyden JM; Hassell JA; Sun X, FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds., Dev Cell 2009 Apr;16(4):607-13

J:151466, Gamer LW; Cox K; Carlo JM; Rosen V, Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures., Dev Dyn 2009 Aug 3;238(9):2374-2381

J:150706, Abler LL; Mansour SL; Sun X, Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung., Dev Dyn 2009 Jul 17;238(8):1999-2013

J:148411, Cameron DA; Pennimpede T; Petkovich M, Tulp3 is a critical repressor of mouse hedgehog signaling., Dev Dyn 2009 May;238(5):1140-9

J:154363, Bluske KK; Kawakami Y; Koyano-Nakagawa N; Nakagawa Y, Differential activity of Wnt/beta-catenin signaling in the embryonic mouse thalamus., Dev Dyn 2009 Nov 18;238(12):3297-3309

J:154370, Heydeck W; Zeng H; Liu A, Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse., Dev Dyn 2009 Oct 29;238(12):3035-3042

J:154373, Town L; McGlinn E; Fiorenza S; Metzis V; Butterfield NC; Richman JM; Wicking C, The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors., Dev Dyn 2009 Oct 29;238(12):3175-3184

J:147287, Retting KN; Song B; Yoon BS; Lyons KM, BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation., Development 2009 Apr;136(7):1093-104

J:147278, Tzchori I; Day TF; Carolan PJ; Zhao Y; Wassif CA; Li L; Lewandoski M; Gorivodsky M; Love PE; Porter FD; Westphal H; Yang Y, LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth., Development 2009 Apr;136(8):1375-85

J:147277, Lan Y; Jiang R, Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth., Development 2009 Apr;136(8):1387-96

J:152851, Huang X; Ketova T; Fleming JT; Wang H; Dey SK; Litingtung Y; Chiang C, Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus., Development 2009 Aug;136(15):2535-43

J:154905, Joeng KS; Long F, The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization., Development 2009 Dec;136(24):4177-85

J:144194, Suzuki K; Yamaguchi Y; Villacorte M; Mihara K; Akiyama M; Shimizu H; Taketo MM; Nakagata N; Tsukiyama T; Yamaguchi TP; Birchmeier W; Kato S; Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling., Development 2009 Feb;136(3):367-72

J:142685, Yu J; Carroll TJ; Rajagopal J; Kobayashi A; Ren Q; McMahon AP, A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney., Development 2009 Jan;136(1):161-71

J:146634, Ohazama A ; Haycraft CJ ; Seppala M ; Blackburn J ; Ghafoor S ; Cobourne M ; Martinelli DC ; Fan CM ; Peterkova R ; Lesot H ; Yoder BK ; Sharpe PT, Primary cilia regulate Shh activity in the control of molar tooth number., Development 2009 Mar;136(6):897-903

J:148018, Sagai T; Amano T; Tamura M; Mizushina Y; Sumiyama K; Shiroishi T, A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings., Development 2009 May;136(10):1665-74

J:148019, Huang J; Dattilo LK; Rajagopal R; Liu Y; Kaartinen V; Mishina Y; Deng CX; Umans L; Zwijsen A; Roberts AB; Beebe DC, FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate., Development 2009 May;136(10):1741-50

J:148020, Hoffmann AD; Peterson MA; Friedland-Little JM; Anderson SA; Moskowitz IP, sonic hedgehog is required in pulmonary endoderm for atrial septation., Development 2009 May;136(10):1761-70

J:147994, Moraes RC; Chang H; Harrington N; Landua JD; Prigge JT; Lane TF; Wainwright BJ; Hamel PA; Lewis MT, Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation., Development 2009 May;136(9):1423-32

J:153618, Ahrens MJ; Li Y; Jiang H; Dudley AT, Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins., Development 2009 Oct;136(20):3463-74

J:153595, Butterfield NC; Metzis V; McGlinn E; Bruce SJ; Wainwright BJ; Wicking C, Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb., Development 2009 Oct;136(20):3515-24

J:150837, Shim JH; Greenblatt MB; Xie M; Schneider MD; Zou W; Zhai B; Gygi S; Glimcher LH, TAK1 is an essential regulator of BMP signalling in cartilage., EMBO J 2009 Jul 22;28(14):2028-41

J:151258, Kolterud A; Grosse AS; Zacharias WJ; Walton KD; Kretovich KE; Madison BB; Waghray M; Ferris JE; Hu C; Merchant JL; Dlugosz AA; Kottmann AH; Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning., Gastroenterology 2009 Aug;137(2):618-28

J:151923, Chen MH; Wilson CW; Li YJ; Law KK; Lu CS; Gacayan R; Zhang X; Hui CC; Chuang PT, Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved., Genes Dev 2009 Aug 15;23(16):1910-28

J:143859, Kessler JD; Hasegawa H; Brun SN; Emmenegger BA; Yang ZJ; Dutton JW; Wang F; Wechsler-Reya RJ, N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma., Genes Dev 2009 Jan 15;23(2):157-70

J:150728, Zhao J; Ding J; Li Y; Ren K; Sha J; Zhu M; Gao X, HnRNP U mediates the long-range regulation of Shh expression during limb development., Hum Mol Genet 2009 Aug 15;18(16):3090-7

J:147584, Patterson VL; Damrau C; Paudyal A; Reeve B; Grimes DT; Stewart ME; Williams DJ; Siggers P; Greenfield A; Murdoch JN, Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway., Hum Mol Genet 2009 May 15;18(10):1719-39

J:147574, Norman RX; Ko HW; Huang V; Eun CM; Abler LL; Zhang Z; Sun X; Eggenschwiler JT, Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling., Hum Mol Genet 2009 May 15;18(10):1740-54

J:147576, Kunisada M; Cui CY; Piao Y; Ko MS; Schlessinger D, Requirement for Shh and Fox family genes at different stages in sweat gland development., Hum Mol Genet 2009 May 15;18(10):1769-78

J:146198, Wall DS; Mears AJ; McNeill B; Mazerolle C; Thurig S; Wang Y; Kageyama R; Wallace VA, Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity., J Cell Biol 2009 Jan 12;184(1):101-12

J:150516, Hu Z; Wang C; Xiao Y; Sheng N; Chen Y; Xu Y; Zhang L; Mo W; Jing N; Hu G, NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development., J Cell Sci 2009 Apr 15;122(Pt 8):1145-54

J:147427, Vue TY; Bluske K; Alishahi A; Yang LL; Koyano-Nakagawa N; Novitch B; Nakagawa Y, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice., J Neurosci 2009 Apr 8;29(14):4484-97

J:145945, Szabo NE; Zhao T; Zhou X; Alvarez-Bolado G, The role of Sonic hedgehog of neural origin in thalamic differentiation in the mouse., J Neurosci 2009 Feb 25;29(8):2453-66

J:149516, Szabo NE; Zhao T; Cankaya M; Theil T; Zhou X; Alvarez-Bolado G, Role of neuroepithelial Sonic hedgehog in hypothalamic patterning., J Neurosci 2009 May 27;29(21):6989-7002

J:149237, Perez-Balaguer A; Puelles E; Wurst W; Martinez S, Shh dependent and independent maintenance of basal midbrain., Mech Dev 2009 May-Jun;126(5-6):301-13

J:153498, In progress, MGI Direct Data Submission 2009;():

J:148989, Schmidt K; Hughes C; Chudek JA; Goodyear SR; Aspden RM; Talbot R; Gundersen TE; Blomhoff R; Henderson C; Wolf CR; Tickle C, Cholesterol metabolism: the main pathway acting downstream of cytochrome P450 oxidoreductase in skeletal development of the limb., Mol Cell Biol 2009 May;29(10):2716-29

J:153980, Matsushita T; Chan YY; Kawanami A; Balmes G; Landreth GE; Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis., Mol Cell Biol 2009 Nov;29(21):5843-57

J:155889, Lin AC; Seeto BL; Bartoszko JM; Khoury MA; Whetstone H; Ho L; Hsu C; Ali AS; Alman BA, Modulating hedgehog signaling can attenuate the severity of osteoarthritis., Nat Med 2009 Dec;15(12):1421-5

J:150524, Chan JA; Balasubramanian S; Witt RM; Nazemi KJ; Choi Y; Pazyra-Murphy MF; Walsh CO; Thompson M; Segal RA, Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses., Nat Neurosci 2009 Apr;12(4):409-17

J:147878, Gao B; Hu J; Stricker S; Cheung M; Ma G; Law KF; Witte F; Briscoe J; Mundlos S; He L; Cheah KS; Chan D, A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range., Nature 2009 Apr 30;458(7242):1196-200

J:147583, Thomas WD; Chen J; Gao YR; Cheung B; Koach J; Sekyere E; Norris MD; Haber M; Ellis T; Wainwright B; Marshall GM, Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression., Oncogene 2009 Apr 2;28(13):1605-15

J:151456, Nakata M; Takada Y; Hishiki T; Saito T; Terui K; Sato Y; Koseki H; Yoshida H, Induction of Wnt5a-expressing mesenchymal cells adjacent to the cloacal plate is an essential process for its proximodistal elongation and subsequent anorectal development., Pediatr Res 2009 Aug;66(2):149-54

J:154102, Cain JE; Islam E; Haxho F; Chen L; Bridgewater D; Nieuwenhuis E; Hui CC; Rosenblum ND, GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells., PLoS One 2009;4(10):e7313

J:153607, Hammond R; Blaess S; Abeliovich A, Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons., PLoS One 2009;4(9):e7007

J:151965, Liem KF Jr; He M; Ocbina PJ; Anderson KV, Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling., Proc Natl Acad Sci U S A 2009 Aug 11;106(32):13377-82

J:151950, Hyman JM; Firestone AJ; Heine VM; Zhao Y; Ocasio CA; Han K; Sun M; Rack PG; Sinha S; Wu JJ; Solow-Cordero DE; Jiang J; Rowitch DH; Chen JK, Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade., Proc Natl Acad Sci U S A 2009 Aug 18;106(33):14132-7

J:146492, Uziel T; Karginov FV; Xie S; Parker JS; Wang YD; Gajjar A; He L; Ellison D; Gilbertson RJ; Hannon G; Roussel MF, The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma., Proc Natl Acad Sci U S A 2009 Feb 24;106(8):2812-7

J:144617, Frappart PO; Lee Y; Russell HR; Chalhoub N; Wang YD; Orii KE; Zhao J; Kondo N; Baker SJ; McKinnon PJ, Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency., Proc Natl Acad Sci U S A 2009 Jan 21;():

J:146777, Tian H; Callahan CA; DuPree KJ; Darbonne WC; Ahn CP; Scales SJ; de Sauvage FJ, Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis., Proc Natl Acad Sci U S A 2009 Mar 17;106(11):4254-9

J:153743, Purcell P; Joo BW; Hu JK; Tran PV; Calicchio ML; O'Connell DJ; Maas RL; Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps., Proc Natl Acad Sci U S A 2009 Oct 27;106(43):18297-302

J:153693, Ayrault O; Godeny MD; Dillon C; Zindy F; Fitzgerald P; Roussel MF; Beere HM, Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma., Proc Natl Acad Sci U S A 2009 Oct 6;106(40):17037-42

J:144933, Benazet JD; Bischofberger M; Tiecke E; Goncalves A; Martin JF; Zuniga A; Naef F; Zeller R, A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning., Science 2009 Feb 20;323(5917):1050-3

J:132011, Sun J; Chen H; Chen C; Whitsett JA; Mishina Y; Bringas P Jr; Ma JC; Warburton D; Shi W, Prenatal lung epithelial cell-specific abrogation of alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation., Am J Pathol 2008 Mar;172(3):571-82

J:139978, Dakubo GD; Beug ST; Mazerolle CJ; Thurig S; Wang Y; Wallace VA, Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells., Brain Res 2008 Sep 4;1228():27-42

J:139573, Yang ZJ; Ellis T; Markant SL; Read TA; Kessler JD; Bourboulas M; Schuller U; Machold R; Fishell G; Rowitch DH; Wainwright BJ; Wechsler-Reya RJ, Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells., Cancer Cell 2008 Aug 12;14(2):135-45

J:141160, Dierks C; Beigi R; Guo GR; Zirlik K; Stegert MR; Manley P; Trussell C; Schmitt-Graeff A; Landwerlin K; Veelken H; Warmuth M, Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation., Cancer Cell 2008 Sep 9;14(3):238-49

J:133329, Becher OJ; Hambardzumyan D; Fomchenko EI; Momota H; Mainwaring L; Bleau AM; Katz AM; Edgar M; Kenney AM; Cordon-Cardo C; Blasberg RG; Holland EC, Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas., Cancer Res 2008 Apr 1;68(7):2241-9

J:140638, Corcoran RB; Bachar Raveh T; Barakat MT; Lee EY; Scott MP, Insulin-like growth factor 2 is required for progression to advanced medulloblastoma in patched1 heterozygous mice., Cancer Res 2008 Nov 1;68(21):8788-95

J:139958, Tanori M; Mancuso M; Pasquali E; Leonardi S; Rebessi S; Di Majo V; Guilly MN; Giangaspero F; Covelli V; Pazzaglia S; Saran A, PARP-1 cooperates with Ptc1 to suppress medulloblastoma and basal cell carcinoma., Carcinogenesis 2008 Oct;29(10):1911-9

J:135990, Lin S; Ikegami M; Xu Y; Bosserhoff AK; Malkinson AM; Shannon JM, Misexpression of MIA disrupts lung morphogenesis and causes neonatal death., Dev Biol 2008 Apr 15;316(2):441-55

J:131988, Han D; Jeon S; Sohn DH; Lee C; Ahn S; Kim WK; Chung H; Seong RH, SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development., Dev Biol 2008 Mar 1;315(1):136-46

J:132568, Glotzer DJ; Zelzer E; Olsen BR, Impaired skin and hair follicle development in Runx2 deficient mice., Dev Biol 2008 Mar 15;315(2):459-73

J:135151, Sigulinsky CL; Green ES; Clark AM; Levine EM, Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina., Dev Biol 2008 May 15;317(2):560-75

J:139732, Ribes V; Stutzmann F; Bianchetti L; Guillemot F; Dolle P; Le Roux I, Combinatorial signalling controls Neurogenin2 expression at the onset of spinal neurogenesis., Dev Biol 2008 Sep 15;321(2):470-81

J:135170, Mak KK; Bi Y; Wan C; Chuang PT; Clemens T; Young M; Yang Y, Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression., Dev Cell 2008 May;14(5):674-88

J:135169, Ohba S; Kawaguchi H; Kugimiya F; Ogasawara T; Kawamura N; Saito T; Ikeda T; Fujii K; Miyajima T; Kuramochi A; Miyashita T; Oda H; Nakamura K; Takato T; Chung UI, Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity., Dev Cell 2008 May;14(5):689-99

J:135168, Capurro MI; Xu P; Shi W; Li F; Jia A; Filmus J, Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding., Dev Cell 2008 May;14(5):700-11

J:132977, McGlinn E; Richman JM; Metzis V; Town L; Butterfield NC; Wainwright BJ; Wicking C, Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb., Dev Dyn 2008 Apr;237(4):1172-82

J:132940, Lin W; Zhang Z; Srajer G; Chen YC; Huang M; Phan HM; Dent SY, Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos., Dev Dyn 2008 Apr;237(4):928-40

J:142646, Yi L; Domyan ET; Lewandoski M; Sun X, Fibroblast growth factor 9 signaling inhibits airway smooth muscle differentiation in mouse lung., Dev Dyn 2008 Dec 18;238(1):123-137

J:130163, Ratzka A; Kalus I; Moser M; Dierks T; Mundlos S; Vortkamp A, Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development., Dev Dyn 2008 Feb;237(2):339-53

J:134674, Fogel JL; Chiang C; Huang X; Agarwala S, Ventral specification and perturbed boundary formation in the mouse midbrain in the absence of Hedgehog signaling., Dev Dyn 2008 May;237(5):1359-72

J:139635, Huang X; Goudy SL; Ketova T; Litingtung Y; Chiang C, Gli3-deficient mice exhibit cleft palate associated with abnormal tongue development., Dev Dyn 2008 Sep 24;237(10):3079-3087

J:133600, Aoki M; Kiyonari H; Nakamura H; Okamoto H, R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development., Dev Growth Differ 2008 Feb;50(2):85-95

J:144627, He F; Xiong W; Yu X; Espinoza-Lewis R; Liu C; Gu S; Nishita M; Suzuki K; Yamada G; Minami Y; Chen Y, Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development., Development 2008 Dec;135(23):3871-9

J:144626, Liu W; Lan Y; Pauws E; Meester-Smoor MA; Stanier P; Zwarthoff EC; Jiang R, The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice., Development 2008 Dec;135(23):3959-68

J:142506, Hoover AN; Wynkoop A; Zeng H; Jia J; Niswander LA; Liu A, C2cd3 is required for cilia formation and Hedgehog signaling in mouse., Development 2008 Dec;135(24):4049-58

J:137353, Sohaskey ML; Yu J; Diaz MA; Plaas AH; Harland RM, JAWS coordinates chondrogenesis and synovial joint positioning., Development 2008 Jul;135(13):2215-20

J:134987, Mak KK; Kronenberg HM; Chuang PT; Mackem S; Yang Y, Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy., Development 2008 Jun;135(11):1947-56

J:132152, Chamberlain CE; Jeong J; Guo C; Allen BL; McMahon AP, Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning., Development 2008 Mar;135(6):1097-106

J:134643, Goddeeris MM; Rho S; Petiet A; Davenport CL; Johnson GA; Meyers EN; Klingensmith J, Intracardiac septation requires hedgehog-dependent cellular contributions from outside the heart., Development 2008 May;135(10):1887-95

J:134483, Rajagopal J; Carroll TJ; Guseh JS; Bores SA; Blank LJ; Anderson WJ; Yu J; Zhou Q; McMahon AP; Melton DA, Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme., Development 2008 May;135(9):1625-34

J:143442, Sanchez-Camacho C; Bovolenta P, Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons., Development 2008 Nov;135(21):3531-41

J:143585, Yu W; McDonnell K; Taketo MM; Bai CB, Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner., Development 2008 Nov;135(22):3687-96

J:143587, Tang H; Brennan J; Karl J; Hamada Y; Raetzman L; Capel B, Notch signaling maintains Leydig progenitor cells in the mouse testis., Development 2008 Nov;135(22):3745-53

J:138769, Caubit X; Lye CM; Martin E; Core N; Long DA; Vola C; Jenkins D; Garratt AN; Skaer H; Woolf AS; Fasano L, Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4., Development 2008 Oct;135(19):3301-10

J:138814, Lavine KJ; Long F; Choi K; Smith C; Ornitz DM, Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development., Development 2008 Sep;135(18):3161-71

J:141804, Fendrich V; Esni F; Garay MV; Feldmann G; Habbe N; Jensen JN; Dor Y; Stoffers D; Jensen J; Leach SD; Maitra A, Hedgehog signaling is required for effective regeneration of exocrine pancreas., Gastroenterology 2008 Aug;135(2):621-31

J:139508, Gao J; DeRouen MC; Chen CH; Nguyen M; Nguyen NT; Ido H; Harada K; Sekiguchi K; Morgan BA; Miner JH; Oro AE; Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis., Genes Dev 2008 Aug 1;22(15):2111-24

J:132983, Zhao H; Ayrault O; Zindy F; Kim JH; Roussel MF, Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development., Genes Dev 2008 Mar 15;22(6):722-727

J:132980, Briggs KJ; Corcoran-Schwartz IM; Zhang W; Harcke T; Devereux WL; Baylin SB; Eberhart CG; Watkins DN, Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma., Genes Dev 2008 Mar 15;22(6):770-85

J:143455, Settembre C; Arteaga-Solis E; McKee MD; de Pablo R; Al Awqati Q; Ballabio A; Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification., Genes Dev 2008 Oct 1;22(19):2645-50

J:136877, Napierala D; Sam K; Morello R; Zheng Q; Munivez E; Shivdasani RA; Lee B, Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome., Hum Mol Genet 2008 Jul 15;17(14):2244-54

J:138862, Warr N; Powles-Glover N; Chappell A; Robson J; Norris D; Arkell RM, Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation., Hum Mol Genet 2008 Oct 1;17(19):2986-96

J:146351, Li Z; Zhang H; Denhard LA; Liu LH; Zhou H; Lan ZJ, Reduced white fat mass in adult mice bearing a truncated Patched 1., Int J Biol Sci 2008;4(1):29-36

J:143554, Wendling DS; Luck C; von Schweinitz D; Kappler R, Characteristic overexpression of the forkhead box transcription factor Foxf1 in Patched-associated tumors., Int J Mol Med 2008 Dec;22(6):787-92

J:143910, Li M; Li C; Liu YH; Xing Y; Hu L; Borok Z; Kwong KY; Minoo P, Mesodermal Deletion of Transforming Growth Factor-{beta} Receptor II Disrupts Lung Epithelial Morphogenesis: cross-talk between TGF-{beta} and Sonic hedgehog pathways., J Biol Chem 2008 Dec 26;283(52):36257-64

J:138557, Pallerla SR; Lawrence R; Lewejohann L; Pan Y; Fischer T; Schlomann U; Zhang X; Esko JD; Grobe K, Altered heparan sulfate structure in mice with deleted NDST3 gene function., J Biol Chem 2008 Jun 13;283(24):16885-94

J:148141, Wu Q; Chen D; Zuscik MJ; O'Keefe RJ; Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin., J Bone Miner Res 2008 Apr;23(4):552-63

J:141416, Leonard JM; Ye H; Wetmore C; Karnitz LM, Sonic Hedgehog signaling impairs ionizing radiation-induced checkpoint activation and induces genomic instability., J Cell Biol 2008 Nov 3;183(3):385-91

J:137685, Lavine KJ; Kovacs A; Ornitz DM, Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice., J Clin Invest 2008 Jul;118(7):2404-14

J:142730, Omenetti A; Porrello A; Jung Y; Yang L; Popov Y; Choi SS; Witek RP; Alpini G; Venter J; Vandongen HM; Syn WK; Baroni GS; Benedetti A; Schuppan D; Diehl AM, Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans., J Clin Invest 2008 Oct;118(10):3331-42

J:139256, Driver EC; Pryor SP; Hill P; Turner J; Ruther U; Biesecker LG; Griffith AJ; Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans., J Neurosci 2008 Jul 16;28(29):7350-8

J:142500, Willaredt MA; Hasenpusch-Theil K; Gardner HA; Kitanovic I; Hirschfeld-Warneken VC; Gojak CP; Gorgas K; Bradford CL; Spatz J; Wolfl S; Theil T; Tucker KL, A crucial role for primary cilia in cortical morphogenesis., J Neurosci 2008 Nov 26;28(48):12887-900

J:141874, Cheng W; Yeung CK; Ng YK; Zhang JR; Hui CC; Kim PC, Sonic Hedgehog mediator Gli2 regulates bladder mesenchymal patterning., J Urol 2008;180(4):1543-50

J:135300, Babbs C; Furniss D; Morriss-Kay GM; Wilkie AO, Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog., Mech Dev 2008 May-Jun;125(5-6):517-26

J:133725, Tran PV; Haycraft CJ; Besschetnova TY; Turbe-Doan A; Stottmann RW; Herron BJ; Chesebro AL; Qiu H; Scherz PJ; Shah JV; Yoder BK; Beier DR, THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia., Nat Genet 2008 Apr;40(4):403-10

J:141958, Hoseong Yang S; Andl T; Grachtchouk V; Wang A; Liu J; Syu LJ; Ferris J; Wang TS; Glick AB; Millar SE; Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling., Nat Genet 2008 Aug 1;():

J:135664, Han YG; Spassky N; Romaguera-Ros M; Garcia-Verdugo JM; Aguilar A; Schneider-Maunoury S; Alvarez-Buylla A, Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells., Nat Neurosci 2008 Mar;11(3):277-84

J:131535, De Langhe SP; Carraro G; Tefft D; Li C; Xu X; Chai Y; Minoo P; Hajihosseini MK; Drouin J; Kaartinen V; Bellusci S, Formation and Differentiation of Multiple Mesenchymal Lineages during Lung Development Is Regulated by beta-catenin Signaling., PLoS ONE 2008;3(1):e1516

J:144081, Andersson ER; Prakash N; Cajanek L; Minina E; Bryja V; Bryjova L; Yamaguchi TP; Hall AC; Wurst W; Arenas E, Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo., PLoS ONE 2008;3(10):e3517

J:144348, Ohazama A; Johnson EB; Ota MS; Choi HJ; Porntaveetus T; Oommen S; Itoh N; Eto K; Gritli-Linde A; Herz J; Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development., PLoS ONE 2008;3(12):e4092

J:154087, Trimarchi JM; Stadler MB; Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression., PLoS One 2008;3(2):e1588

J:138971, Mancuso M; Pasquali E; Leonardi S; Tanori M; Rebessi S; Di Majo V; Pazzaglia S; Toni MP; Pimpinella M; Covelli V; Saran A, Oncogenic bystander radiation effects in Patched heterozygous mouse cerebellum., Proc Natl Acad Sci U S A 2008 Aug 26;105(34):12445-50

J:131828, Kobayashi T; Lu J; Cobb BS; Rodda SJ; McMahon AP; Schipani E; Merkenschlager M; Kronenberg HM, Dicer-dependent pathways regulate chondrocyte proliferation and differentiation., Proc Natl Acad Sci U S A 2008 Feb 12;105(6):1949-54

J:137825, Passman JN; Dong XR; Wu SP; Maguire CT; Hogan KA; Bautch VL; Majesky MW, A sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1+ smooth muscle progenitor cells., Proc Natl Acad Sci U S A 2008 Jul 8;105(27):9349-54

J:144057, Hockman D; Cretekos CJ; Mason MK; Behringer RR; Jacobs DS; Illing N, A second wave of Sonic hedgehog expression during the development of the bat limb., Proc Natl Acad Sci U S A 2008 Nov 4;105(44):16982-7

J:139130, Breunig JJ; Sarkisian MR; Arellano JI; Morozov YM; Ayoub AE; Sojitra S; Wang B; Flavell RA; Rakic P; Town T, Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling., Proc Natl Acad Sci U S A 2008 Sep 2;105(35):13127-32

J:133905, Koyama E; Ochiai T; Rountree RB; Kingsley DM; Enomoto-Iwamoto M; Iwamoto M; Pacifici M, Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling., Ann N Y Acad Sci 2007 Nov;1116():100-12

J:127207, Uhmann A; Dittmann K; Nitzki F; Dressel R; Koleva M; Frommhold A; Zibat A; Binder C; Adham I; Nitsche M; Heller T; Armstrong V; Schulz-Schaeffer W; Wienands J; Hahn H, The Hedgehog receptor Patched controls lymphoid lineage commitment., Blood 2007 Sep 15;110(6):1814-23

J:119916, Yang HS; Hinds PW, pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development., BMC Dev Biol 2007;7():6

J:120317, Zindy F; Uziel T; Ayrault O; Calabrese C; Valentine M; Rehg JE; Gilbertson RJ; Sherr CJ; Roussel MF, Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors., Cancer Res 2007 Mar 15;67(6):2676-84

J:130260, Van Dyck F; Braem CV; Chen Z; Declercq J; Deckers R; Kim BM; Ito S; Wu MK; Cohen DE; Dewerchin M; Derua R; Waelkens E; Fiette L; Roebroek A; Schuit F; Van de Ven WJ; Shivdasani RA, Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons., Cell Metab 2007 Nov;6(5):406-13

J:124121, Galvin KE; Ye H; Wetmore C, Differential gene induction by genetic and ligand-mediated activation of the Sonic hedgehog pathway in neural stem cells., Dev Biol 2007 Aug 15;308(2):331-42

J:124084, Scherz PJ; McGlinn E; Nissim S; Tabin CJ, Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb., Dev Biol 2007 Aug 15;308(2):343-54

J:124280, Nieuwenhuis E; Barnfield PC; Makino S; Hui CC, Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1., Dev Biol 2007 Aug 15;308(2):547-60

J:122952, Hung IH; Yu K; Lavine KJ; Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod., Dev Biol 2007 Jul 15;307(2):300-13

J:122563, Wang G; Woods A; Agoston H; Ulici V; Glogauer M; Beier F, Genetic ablation of Rac1 in cartilage results in chondrodysplasia., Dev Biol 2007 Jun 15;306(2):612-23

J:119142, Soukkarieh C; Agius E; Soula C; Cochard P, Pax2 regulates neuronal-glial cell fate choice in the embryonic optic nerve., Dev Biol 2007 Mar 15;303(2):800-13

J:121342, Song B; Haycraft CJ; Seo HS; Yoder BK; Serra R, Development of the post-natal growth plate requires intraflagellar transport proteins., Dev Biol 2007 May 1;305(1):202-16

J:121301, Mau E; Whetstone H; Yu C; Hopyan S; Wunder JS; Alman BA, PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms., Dev Biol 2007 May 1;305(1):28-39

J:121311, Liu Z; Yu S; Manley NR, Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia., Dev Biol 2007 May 1;305(1):333-46

J:121344, Pachikara A; Dolson DK; Martinu L; Riccomagno MM; Jeong Y; Epstein DJ, Activation of Class I transcription factors by low level Sonic hedgehog signaling is mediated by Gli2-dependent and independent mechanisms., Dev Biol 2007 May 1;305(1):52-62

J:121609, Wang C; Ruther U; Wang B, The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning., Dev Biol 2007 May 15;305(2):460-9

J:124871, Kolpakova-Hart E; Jinnin M; Hou B; Fukai N; Olsen BR, Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms., Dev Biol 2007 Sep 15;309(2):273-84

J:117334, Gritli-Linde A; Hallberg K; Harfe BD; Reyahi A; Kannius-Janson M; Nilsson J; Cobourne MT; Sharpe PT; McMahon AP; Linde A, Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling., Dev Cell 2007 Jan;12(1):99-112

J:120712, Caspary T; Larkins CE; Anderson KV, The graded response to sonic hedgehog depends on cilia architecture., Dev Cell 2007 May;12(5):767-78

J:117221, Shibukawa Y; Young B; Wu C; Yamada S; Long F; Pacifici M; Koyama E, Temporomandibular joint formation and condyle growth require Indian hedgehog signaling., Dev Dyn 2007 Feb;236(2):426-34

J:118340, Wang C; Pan Y; Wang B, A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype., Dev Dyn 2007 Mar;236(3):769-76

J:135131, Kashiwagi M; Morgan BA; Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny., Development 2007 Apr;134(8):1571-82

J:135134, Goddeeris MM; Schwartz R; Klingensmith J; Meyers EN, Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development., Development 2007 Apr;134(8):1593-604

J:124105, Ruiz-Perez VL; Blair HJ; Rodriguez-Andres ME; Blanco MJ; Wilson A; Liu YN; Miles C; Peters H; Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia., Development 2007 Aug;134(16):2903-12

J:129204, Robertson EJ; Charatsi I; Joyner CJ; Koonce CH; Morgan M; Islam A; Paterson C; Lejsek E; Arnold SJ; Kallies A; Nutt SL; Bikoff EK, Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice., Development 2007 Dec;134(24):4335-45

J:119913, Haraguchi R; Motoyama J; Sasaki H; Satoh Y; Miyagawa S; Nakagata N; Moon A; Yamada G, Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling., Development 2007 Feb;134(3):525-33

J:117033, Haycraft CJ; Zhang Q; Song B; Jackson WS; Detloff PJ; Serra R; Yoder BK, Intraflagellar transport is essential for endochondral bone formation., Development 2007 Jan;134(2):307-16

J:122745, Vierkotten J; Dildrop R; Peters T; Wang B; Ruther U, Ftm is a novel basal body protein of cilia involved in Shh signalling., Development 2007 Jul;134(14):2569-77

J:122547, Huang X; Litingtung Y; Chiang C, Region-specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord., Development 2007 Jun;134(11):2095-105

J:118936, Moraes RC; Zhang X; Harrington N; Fung JY; Wu MF; Hilsenbeck SG; Allred DC; Lewis MT, Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia., Development 2007 Mar;134(6):1231-42

J:121411, Vokes SA; Ji H; McCuine S; Tenzen T; Giles S; Zhong S; Longabaugh WJ; Davidson EH; Wong WH; McMahon AP, Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning., Development 2007 May;134(10):1977-89

J:121232, Bok J; Dolson DK; Hill P; Ruther U; Epstein DJ; Wu DK, Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear., Development 2007 May;134(9):1713-22

J:128323, Shiroyanagi Y; Liu B; Cao M; Agras K; Li J; Hsieh MH; Willingham EJ; Baskin LS, Urothelial sonic hedgehog signaling plays an important role in bladder smooth muscle formation., Differentiation 2007 Dec;75(10):968-77

J:121824, De Bortoli M; Castellino RC; Skapura DG; Shen JJ; Su JM; Russell HV; Hicks MJ; Man TK; Kim JY, Patched haploinsufficient mouse rhabdomyosarcoma overexpress secreted phosphoprotein 1 and matrix metalloproteinases., Eur J Cancer 2007 May;43(8):1308-1317

J:115165, Hecht J; Seitz V; Urban M; Wagner F; Robinson PN; Stiege A; Dieterich C; Kornak U; Wilkening U; Brieske N; Zwingman C; Kidess A; Stricker S; Mundlos S, Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model., Gene Expr Patterns 2007 Jan;7(1-2):102-12

J:127131, Ueda T; Watanabe-Fukunaga R; Ogawa H; Fukuyama H; Higashi Y; Nagata S; Fukunaga R, Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis., Genes Cells 2007 May;12(5):581-92

J:121554, Martinelli DC; Fan CM, Gas1 extends the range of Hedgehog action by facilitating its signaling., Genes Dev 2007 May 15;21(10):1231-43

J:121553, Allen BL; Tenzen T; McMahon AP, The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development., Genes Dev 2007 May 15;21(10):1244-57

J:121700, Kolanczyk M; Kossler N; Kuhnisch J; Lavitas L; Stricker S; Wilkening U; Manjubala I; Fratzl P; Sporle R; Herrmann BG; Parada LF; Kornak U; Mundlos S, Multiple roles for neurofibromin in skeletal development and growth., Hum Mol Genet 2007 Apr 15;16(8):874-86

J:125109, Huang X; Litingtung Y; Chiang C, Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly., Hum Mol Genet 2007 Jun 15;16(12):1454-68

J:125087, Hill P; Wang B; Ruther U, The molecular basis of Pallister Hall associated polydactyly., Hum Mol Genet 2007 Sep 1;16(17):2089-96

J:132006, Eichenmuller M; Bauer R; Von Schweinitz D; Hahn H; Kappler R, Hedgehog-independent overexpression of transforming growth factor-beta1 in rhabdomyosarcoma of Patched1 mutant mice., Int J Oncol 2007 Aug;31(2):405-12

J:130545, Singh S; Robinson M; Nahi F; Coley B; Robinson ML; Bates CM; Kornacker K; McHugh KM, Identification of a unique transgenic mouse line that develops megabladder, obstructive uropathy, and renal dysfunction., J Am Soc Nephrol 2007 Feb;18(2):461-71

J:135374, Patra D; Xing X; Davies S; Bryan J; Franz C; Hunziker EB; Sandell LJ, Site-1 protease is essential for endochondral bone formation in mice., J Cell Biol 2007 Nov 19;179(4):687-700

J:122159, Seppala M; Depew MJ; Martinelli DC; Fan CM; Sharpe PT; Cobourne MT, Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog., J Clin Invest 2007 Jun;117(6):1575-84

J:121105, Matsumoto Y; Irie F; Inatani M; Tessier-Lavigne M; Yamaguchi Y, Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate., J Neurosci 2007 Apr 18;27(16):4342-50

J:125229, Welsh IC; Hagge-Greenberg A; O'brien TP, A dosage-dependent role for Spry2 in growth and patterning during palate development., Mech Dev 2007 Sep-Oct;124(9-10):746-61

J:129050, Yun JS; Rust JM; Ishimaru T; Diaz E, A novel role of the Mad family member Mad3 in cerebellar granule neuron precursor proliferation., Mol Cell Biol 2007 Dec;27(23):8178-89

J:126364, Merchan P; Bribian A; Sanchez-Camacho C; Lezameta M; Bovolenta P; de Castro F, Sonic hedgehog promotes the migration and proliferation of optic nerve oligodendrocyte precursors., Mol Cell Neurosci 2007 Nov;36(3):355-368

J:118622, Wakabayashi Y; Mao JH; Brown K; Girardi M; Balmain A, Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice., Nature 2007 Feb 15;445(7129):761-5

J:132162, Petryniak MA; Potter GB; Rowitch DH; Rubenstein JL, Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain., Neuron 2007 Aug 2;55(3):417-33

J:125534, Lee Y; Kawagoe R; Sasai K; Li Y; Russell HR; Curran T; McKinnon PJ, Loss of suppressor-of-fused function promotes tumorigenesis., Oncogene 2007 Sep 27;26(44):6442-7

J:133665, Saran A; Pazzaglia S; Mancuso M; Rebessi S; Di Majo V; Tanori M; Lovisolo GA; Pinto R; Marino C, Effects of exposure of newborn patched1 heterozygous mice to GSM, 900 MHz., Radiat Res 2007 Dec;168(6):733-40

J:123161, Rohatgi R; Milenkovic L; Scott MP, Patched1 regulates hedgehog signaling at the primary cilium., Science 2007 Jul 20;317(5836):372-6

J:111078, Sicklick JK; Li YX; Melhem A; Schmelzer E; Zdanowicz M; Huang J; Caballero M; Fair JH; Ludlow JW; McClelland RE; Reid LM; Diehl AM, Hedgehog signaling maintains resident hepatic progenitors throughout life., Am J Physiol Gastrointest Liver Physiol 2006 May;290(5):G859-70

J:112573, Uchikawa H; Toyoda M; Nagao K; Miyauchi H; Nishikawa R; Fujii K; Kohno Y; Yamada M; Miyashita T, Brain- and heart-specific Patched-1 containing exon 12b is a dominant negative isoform and is expressed in medulloblastomas., Biochem Biophys Res Commun 2006 Oct 13;349(1):277-83

J:110402, Caty V; Liu Y; Viau G; Bissonnette R, Multiple large surface photodynamic therapy sessions with topical methylaminolaevulinate in PTCH heterozygous mice., Br J Dermatol 2006 Apr;154(4):740-2

J:107056, Pazzaglia S, Ptc1 heterozygous knockout mice as a model of multi-organ tumorigenesis., Cancer Lett 2006 Mar 28;234(2):124-34

J:106653, Adolphe C; Hetherington R; Ellis T; Wainwright B, Patched1 functions as a gatekeeper by promoting cell cycle progression., Cancer Res 2006 Feb 15;66(4):2081-8

J:110565, Mancuso M; Leonardi S; Tanori M; Pasquali E; Pierdomenico M; Rebessi S; Di Majo V; Covelli V; Pazzaglia S; Saran A, Hair cycle-dependent basal cell carcinoma tumorigenesis in Ptc1neo67/+ mice exposed to radiation., Cancer Res 2006 Jul 1;66(13):6606-14

J:112118, Lee Y; Miller HL; Russell HR; Boyd K; Curran T; McKinnon PJ, Patched2 modulates tumorigenesis in patched1 heterozygous mice., Cancer Res 2006 Jul 15;66(14):6964-71

J:114992, Mao J; Ligon KL; Rakhlin EY; Thayer SP; Bronson RT; Rowitch D; McMahon AP, A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway., Cancer Res 2006 Oct 15;66(20):10171-8

J:107537, Uziel T; Zindy F; Sherr CJ; Roussel MF, The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma., Cell Cycle 2006 Feb;5(4):363-5

J:122447, Asai J; Takenaka H; Kusano KF; Ii M; Luedemann C; Curry C; Eaton E; Iwakura A; Tsutsumi Y; Hamada H; Kishimoto S; Thorne T; Kishore R; Losordo DW, Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling., Circulation 2006 May 23;113(20):2413-24

J:119323, Atit R; Sgaier SK; Mohamed OA; Taketo MM; Dufort D; Joyner AL; Niswander L; Conlon RA, Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse., Dev Biol 2006 Aug 1;296(1):164-76

J:119664, Houde C; Dickinson RJ; Houtzager VM; Cullum R; Montpetit R; Metzler M; Simpson EM; Roy S; Hayden MR; Hoodless PA; Nicholson DW, Hippi is essential for node cilia assembly and Sonic hedgehog signaling., Dev Biol 2006 Dec 15;300(2):523-33

J:144308, Ovchinnikov DA; Selever J; Wang Y; Chen YT; Mishina Y; Martin JF; Behringer RR, BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning., Dev Biol 2006 Jul 1;295(1):103-15

J:110699, Boras-Granic K; Chang H; Grosschedl R; Hamel PA, Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland., Dev Biol 2006 Jul 1;295(1):219-31

J:110617, Stottmann RW; Berrong M; Matta K; Choi M; Klingensmith J, The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms., Dev Biol 2006 Jul 15;295(2):647-63

J:106405, Mackay DR; Hu M; Li B; Rheaume C; Dai X, The mouse Ovol2 gene is required for cranial neural tube development., Dev Biol 2006 Mar 1;291(1):38-52

J:108713, Itaranta P; Chi L; Seppanen T; Niku M; Tuukkanen J; Peltoketo H; Vainio S, Wnt-4 signaling is involved in the control of smooth muscle cell fate via Bmp-4 in the medullary stroma of the developing kidney., Dev Biol 2006 May 15;293(2):473-83

J:114714, DeLaurier A; Schweitzer R; Logan M, Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb., Dev Biol 2006 Nov 1;299(1):22-34

J:105832, Svard J; Henricson KH; Persson-Lek M; Rozell B; Lauth M; Bergstrom A; Ericson J; Toftgard R; Teglund S, Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway., Dev Cell 2006 Feb;10(2):187-97

J:108747, Tenzen T; Allen BL; Cole F; Kang JS; Krauss RS; McMahon AP, The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice., Dev Cell 2006 May;10(5):647-56

J:108746, Zhang W; Kang JS; Cole F; Yi MJ; Krauss RS, Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly., Dev Cell 2006 May;10(5):657-65

J:106158, Furimsky M; Wallace VA, Complementary Gli activity mediates early patterning of the mouse visual system., Dev Dyn 2006 Mar;235(3):594-605

J:144140, Hill TP; Taketo MM; Birchmeier W; Hartmann C, Multiple roles of mesenchymal beta-catenin during murine limb patterning., Development 2006 Apr;133(7):1219-29

J:107406, White AC; Xu J; Yin Y; Smith C; Schmid G; Ornitz DM, FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains., Development 2006 Apr;133(8):1507-17

J:107400, Laurikkala J; Mikkola ML; James M; Tummers M; Mills AA; Thesleff I, p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation., Development 2006 Apr;133(8):1553-63

J:119030, Spater D; Hill TP; O'sullivan RJ; Gruber M; Conner DA; Hartmann C, Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis., Development 2006 Aug;133(15):3039-49

J:119669, Yoon BS; Pogue R; Ovchinnikov DA; Yoshii I; Mishina Y; Behringer RR; Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways., Development 2006 Dec;133(23):4667-78

J:104523, Ribes V; Wang Z; Dolle P; Niederreither K, Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling., Development 2006 Jan;133(2):351-61

J:109528, Capellini TD; Di Giacomo G; Salsi V; Brendolan A; Ferretti E; Srivastava D; Zappavigna V; Selleri L, Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression., Development 2006 Jun;133(11):2263-73

J:109474, Ilagan R; Abu-Issa R; Brown D; Yang YP; Jiao K; Schwartz RJ; Klingensmith J; Meyers EN, Fgf8 is required for anterior heart field development., Development 2006 Jun;133(12):2435-45

J:108521, Heiser PW; Lau J; Taketo MM; Herrera PL; Hebrok M, Stabilization of {beta}-catenin impacts pancreas growth., Development 2006 May;133(10):2023-32

J:108507, Corrales JD; Blaess S; Mahoney EM; Joyner AL, The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation., Development 2006 May;133(9):1811-21

J:119563, Alt B; Elsalini OA; Schrumpf P; Haufs N; Lawson ND; Schwabe GC; Mundlos S; Gruters A; Krude H; Rohr KB, Arteries define the position of the thyroid gland during its developmental relocalisation., Development 2006 Oct;133(19):3797-804

J:115956, Pogoriler J; Millen K; Utset M; Du W, Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation., Development 2006 Oct;133(19):3929-37

J:112460, Hatsell SJ; Cowin P, Gli3-mediated repression of Hedgehog targets is required for normal mammary development., Development 2006 Sep;133(18):3661-70

J:112462, Mak KK; Chen MH; Day TF; Chuang PT; Yang Y, Wnt/{beta}-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation., Development 2006 Sep;133(18):3695-707

J:112701, Bailey PJ; Klos JM; Andersson E; Karlen M; Kallstrom M; Ponjavic J; Muhr J; Lenhard B; Sandelin A; Ericson J, A global genomic transcriptional code associated with CNS-expressed genes., Exp Cell Res 2006 Oct 1;312(16):3108-19

J:124918, Spencer-Dene B; Sala FG; Bellusci S; Gschmeissner S; Stamp G; Dickson C, Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling., Gastroenterology 2006 Apr;130(4):1233-44

J:104154, Rice R; Connor E; Rice DP, Expression patterns of Hedgehog signalling pathway members during mouse palate development., Gene Expr Patterns 2006 Jan;6(2):206-12

J:111685, Asayesh A; Sharpe J; Watson RP; Hecksher-Sorensen J; Hastie ND; Hill RE; Ahlgren U, Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice., Genes Dev 2006 Aug 15;20(16):2208-13

J:103820, Reiter JF; Skarnes WC, Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition., Genes Dev 2006 Jan 1;20(1):22-7

J:114852, Jiang F; Herman GE, Analysis of Nsdhl-deficient embryos reveals a role for Hedgehog signaling in early placental development., Hum Mol Genet 2006 Nov 15;15(22):3293-305

J:128121, Chen X; Macica CM; Dreyer BE; Hammond VE; Hens JR; Philbrick WM; Broadus AE, Initial characterization of PTH-related protein gene-driven lacZ expression in the mouse., J Bone Miner Res 2006 Jan;21(1):113-23

J:113301, James MJ; Jarvinen E; Wang XP; Thesleff I, Different roles of Runx2 during early neural crest-derived bone and tooth development., J Bone Miner Res 2006 Jul;21(7):1034-44

J:106499, Airik R; Bussen M; Singh MK; Petry M; Kispert A, Tbx18 regulates the development of the ureteral mesenchyme., J Clin Invest 2006 Mar;116(3):663-74

J:113291, Morita K; Lo Celso C; Spencer-Dene B; Zouboulis CC; Watt FM, HAN11 binds mDia1 and controls GLI1 transcriptional activity., J Dermatol Sci 2006 Oct;44(1):11-20

J:115750, Dakubo GD; Mazerolle CJ; Wallace VA, Expression of Notch and Wnt pathway components and activation of Notch signaling in medulloblastomas from heterozygous patched mice., J Neurooncol 2006 Sep;79(3):221-7

J:112169, Nieuwenhuis E; Motoyama J; Barnfield PC; Yoshikawa Y; Zhang X; Mo R; Crackower MA; Hui CC, Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia., Mol Cell Biol 2006 Sep;26(17):6609-22

J:106035, Ferrante MI; Zullo A; Barra A; Bimonte S; Messaddeq N; Studer M; Dolle P; Franco B, Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification., Nat Genet 2006 Jan;38(1):112-7

J:115846, Pazzaglia S; Tanori M; Mancuso M; Gessi M; Pasquali E; Leonardi S; Oliva MA; Rebessi S; Di Majo V; Covelli V; Giangaspero F; Saran A, Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice., Oncogene 2006 Sep 7;25(40):5575-80

J:109101, Li Y; Zhang H; Litingtung Y; Chiang C, Cholesterol modification restricts the spread of Shh gradient in the limb bud., Proc Natl Acad Sci U S A 2006 Apr 25;103(17):6548-53

J:118250, Mahoney ZX; Sammut B; Xavier RJ; Cunningham J; Go G; Brim KL; Stappenbeck TS; Miner JH; Swat W, Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter., Proc Natl Acad Sci U S A 2006 Dec 26;103(52):19872-7

J:105996, Roper RJ; Baxter LL; Saran NG; Klinedinst DK; Beachy PA; Reeves RH, Defective cerebellar response to mitogenic Hedgehog signaling in Down's syndrome mice., Proc Natl Acad Sci U S A 2006 Jan 31;103(5):1452-6

J:111051, Cui CY; Hashimoto T; Grivennikov SI; Piao Y; Nedospasov SA; Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation., Proc Natl Acad Sci U S A 2006 Jun 13;103(24):9142-7

J:113717, Trowbridge JJ; Scott MP; Bhatia M, Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration., Proc Natl Acad Sci U S A 2006 Sep 19;103(38):14134-9

J:106707, Lien WH; Klezovitch O; Fernandez TE; Delrow J; Vasioukhin V, alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway., Science 2006 Mar 17;311(5767):1609-12

J:96599, Miletich I; Cobourne MT; Abdeen M; Sharpe PT, Expression of the Hedgehog antagonists Rab23 and Slimb/betaTrCP during mouse tooth development., Arch Oral Biol 2005 Feb;50(2):147-51

J:104933, Hilton MJ; Gutierrez L; Martinez DA; Wells DE, EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development., Bone 2005 Mar;36(3):379-86

J:99387, Romer J; Curran T, Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics., Cancer Res 2005 Jun 15;65(12):4975-8

J:100563, Vauclair S; Nicolas M; Barrandon Y; Radtke F, Notch1 is essential for postnatal hair follicle development and homeostasis., Dev Biol 2005 Aug 1;284(1):184-93

J:104611, Moore-Scott BA; Manley NR, Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs., Dev Biol 2005 Feb 15;278(2):323-35

J:99648, Washington Smoak I; Byrd NA; Abu-Issa R; Goddeeris MM; Anderson R; Morris J; Yamamura K; Klingensmith J; Meyers EN, Sonic hedgehog is required for cardiac outflow tract and neural crest cell development., Dev Biol 2005 Jul 15;283(2):357-72

J:103457, Li C; Hu L; Xiao J; Chen H; Li JT; Bellusci S; Delanghe S; Minoo P, Wnt5a regulates Shh and Fgf10 signaling during lung development., Dev Biol 2005 Nov 1;287(1):86-97

J:101265, Kuijper S; Feitsma H; Sheth R; Korving J; Reijnen M; Meijlink F, Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh., Dev Biol 2005 Sep 15;285(2):533-44

J:100687, Mill P; Mo R; Hu MC; Dagnino L; Rosenblum ND; Hui CC, Shh controls epithelial proliferation via independent pathways that converge on N-Myc., Dev Cell 2005 Aug;9(2):293-303

J:98426, Hill TP; Spater D; Taketo MM; Birchmeier W; Hartmann C, Canonical Wnt/beta-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes., Dev Cell 2005 May;8(5):727-38

J:119848, Rawlins EL; Hogan BL, Intercellular growth factor signaling and the development of mouse tracheal submucosal glands., Dev Dyn 2005 Aug;233(4):1378-85

J:102853, Kim JH; Huang Z; Mo R, Gli3 null mice display glandular overgrowth of the developing stomach., Dev Dyn 2005 Dec;234(4):984-91

J:98927, Lipinski RJ; Cook CH; Barnett DH; Gipp JJ; Peterson RE; Bushman W, Sonic hedgehog signaling regulates the expression of insulin-like growth factor binding protein-6 during fetal prostate development., Dev Dyn 2005 Jul;233(3):829-36

J:98357, Bell SM; Schreiner CM; Goetz JA; Robbins DJ; Scott WJ Jr, Shh signaling in limb bud ectoderm: Potential role in teratogen-induced postaxial ectrodactyly., Dev Dyn 2005 Jun;233(2):313-25

J:101172, Gao N; Ishii K; Mirosevich J; Kuwajima S; Oppenheimer SR; Roberts RL; Jiang M; Yu X; Shappell SB; Caprioli RM; Stoffel M; Hayward SW; Matusik RJ, Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation., Development 2005 Aug;132(15):3431-43

J:100425, Grobe K; Inatani M; Pallerla SR; Castagnola J; Yamaguchi Y; Esko JD, Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function., Development 2005 Aug;132(16):3777-86

J:102948, Koziel L; Wuelling M; Schneider S; Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation., Development 2005 Dec;132(23):5249-60

J:94270, Tian H; Jeong J; Harfe BD; Tabin CJ; McMahon AP, Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand., Development 2005 Jan;132(1):133-42

J:94269, Jeong J; McMahon AP, Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1., Development 2005 Jan;132(1):143-54

J:94274, Hu H; Hilton MJ; Tu X; Yu K; Ornitz DM; Long F, Sequential roles of Hedgehog and Wnt signaling in osteoblast development., Development 2005 Jan;132(1):49-60

J:102236, Madison BB; Braunstein K; Kuizon E; Portman K; Qiao XT; Gumucio DL, Epithelial hedgehog signals pattern the intestinal crypt-villus axis., Development 2005 Jan;132(2):279-89

J:95319, Spoelgen R; Hammes A; Anzenberger U; Zechner D; Andersen OM; Jerchow B; Willnow TE, LRP2/megalin is required for patterning of the ventral telencephalon., Development 2005 Jan;132(2):405-14

J:98800, Liu A; Wang B; Niswander LA, Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors., Development 2005 Jul;132(13):3103-11

J:97179, Colnot C; de la Fuente L; Huang S; Hu D; Lu C; St-Jacques B; Helms JA, Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development., Development 2005 Mar;132(5):1057-67

J:98381, Oliver TG; Read TA; Kessler JD; Mehmeti A; Wells JF; Huynh TT; Lin SM; Wechsler-Reya RJ, Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma., Development 2005 May;132(10):2425-39

J:103125, Stickens D; Zak BM; Rougier N; Esko JD; Werb Z, Mice deficient in Ext2 lack heparan sulfate and develop exostoses., Development 2005 Nov;132(22):5055-68

J:101736, Verheyden JM; Lewandoski M; Deng C; Harfe BD; Sun X, Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning., Development 2005 Oct;132(19):4235-45

J:101731, Cooper AF; Yu KP; Brueckner M; Brailey LL; Johnson L; McGrath JM; Bale AE, Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused., Development 2005 Oct;132(19):4407-17

J:128547, Kluppel M; Wight TN; Chan C; Hinek A; Wrana JL, Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis., Development 2005 Sep;132(17):3989-4003

J:97242, Zhang XQ; Afink GB; Hu XR; Nister M; Forsberg-Nilsson K, Gli1 is not required for Pdgfralpha expression during mouse embryonic development., Differentiation 2005 Mar;73(2-3):109-19

J:99408, Riccomagno MM; Takada S; Epstein DJ, Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh., Genes Dev 2005 Jul 1;19(13):1612-23

J:102702, Uziel T; Zindy F; Xie S; Lee Y; Forget A; Magdaleno S; Rehg JE; Calabrese C; Solecki D; Eberhart CG; Sherr SE; Plimmer S; Clifford SC; Hatten ME; McKinnon PJ; Gilbertson RJ; Curran T; Sherr CJ; Roussel MF, The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation., Genes Dev 2005 Nov 15;19(22):2656-67

J:97531, Nagao K; Toyoda M; Takeuchi-Inoue K; Fujii K; Yamada M; Miyashita T, Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exons., Genomics 2005 Apr;85(4):462-71

J:104180, Uhmann A; Ferch U; Bauer R; Tauber S; Arziman Z; Chen C; Hemmerlein B; Wojnowski L; Hahn H, A model for PTCH1/Ptch1-associated tumors comprising mutational inactivation and gene silencing., Int J Oncol 2005 Dec;27(6):1567-75

J:97323, Niedermaier M; Schwabe GC; Fees S; Helmrich A; Brieske N; Seemann P; Hecht J; Seitz V; Stricker S; Leschik G; Schrock E; Selby PB; Mundlos S, An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression., J Clin Invest 2005 Apr 1;115(4):900-909

J:112545, Wang XP; Aberg T; James MJ; Levanon D; Groner Y; Thesleff I, Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth., J Dent Res 2005 Feb;84(2):138-43

J:96412, Sacedon R; Diez B; Nunez V; Hernandez-Lopez C; Gutierrez-Frias C; Cejalvo T; Outram SV; Crompton T; Zapata AG; Vicente A; Varas A, Sonic hedgehog is produced by follicular dendritic cells and protects germinal center B cells from apoptosis., J Immunol 2005 Feb 1;174(3):1456-61

J:95379, Vogt A; Hebert J; Hwang J; Lu Y; Epstein EH, Anti-rejection drug treatment increases Basal cell carcinoma burden in ptch1+/- mice., J Invest Dermatol 2005 Jan;124(1):263-7

J:103577, Lee JL; Kim A; Kopelovich L; Bickers DR; Athar M, Differential expression of E prostanoid receptors in murine and human non-melanoma skin cancer., J Invest Dermatol 2005 Oct;125(4):818-25

J:103007, DiPaola CP; Farmer JC; Manova K; Niswander LA, Molecular signaling in intervertebral disk development., J Orthop Res 2005 Sep;23(5):1112-9

J:102870, Razzaque MS; Soegiarto DW; Chang D; Long F; Lanske B, Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation., J Pathol 2005 Dec;207(4):453-61

J:116391, Merchant M; Evangelista M; Luoh SM; Frantz GD; Chalasani S; Carano RA; van Hoy M; Ramirez J; Ogasawara AK; McFarland LM; Filvaroff EH; French DM; de Sauvage FJ, Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus., Mol Cell Biol 2005 Aug;25(16):7054-68

J:103330, Loulier K; Ruat M; Traiffort E, Analysis of hedgehog interacting protein in the brain and its expression in nitric oxide synthase-positive cells., Neuroreport 2005 Nov 28;16(17):1959-62

J:99548, Kimura H; Stephen D; Joyner A; Curran T, Gli1 is important for medulloblastoma formation in Ptc1+/- mice., Oncogene 2005 Jun 9;24(25):4026-36

J:100466, Huangfu D; Anderson KV, Cilia and Hedgehog responsiveness in the mouse., Proc Natl Acad Sci U S A 2005 Aug 9;102(32):11325-30

J:96101, Haumaitre C; Barbacci E; Jenny M; Ott MO; Gradwohl G; Cereghini S, Lack of TCF2/vHNF1 in mice leads to pancreas agenesis., Proc Natl Acad Sci U S A 2005 Feb 1;102(5):1490-5

J:103829, Chen B; Schaevitz LR; McConnell SK, Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex., Proc Natl Acad Sci U S A 2005 Nov 22;102(47):17184-9

J:99680, The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome, Science 2005;309(5740):1559-1563

J:93296, Yu H; Wessels A; Chen J; Phelps AL; Oatis J; Tint GS; Patel SB, Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome., BMC Dev Biol 2004 Mar 2;4(1):1

J:93535, Romer JT; Kimura H; Magdaleno S; Sasai K; Fuller C; Baines H; Connelly M; Stewart CF; Gould S; Rubin LL; Curran T, Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice., Cancer Cell 2004 Sep;6(3):229-40

J:88072, Mancuso M; Pazzaglia S; Tanori M; Hahn H; Merola P; Rebessi S; Atkinson MJ; Di Majo V; Covelli V; Saran A, Basal cell carcinoma and its development: insights from radiation-induced tumors in ptch1-deficient mice., Cancer Res 2004 Feb 1;64(3):934-41

J:90301, Pazzaglia S; Mancuso M; Tanori M; Atkinson MJ; Merola P; Rebessi S; Di Majo V; Covelli V; Hahn H; Saran A, Modulation of patched-associated susceptibility to radiation induced tumorigenesis by genetic background., Cancer Res 2004 Jun 1;64(11):3798-806

J:89149, Hamed S; LaRue H; Hovington H; Girard J; Jeannotte L; Latulippe E; Fradet Y, Accelerated induction of bladder cancer in patched heterozygous mutant mice., Cancer Res 2004 Mar 15;64(6):1938-42

J:92504, Harfe BD; Scherz PJ; Nissim S; Tian H; McMahon AP; Tabin CJ, Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities., Cell 2004 Aug 20;118(4):517-28

J:92177, Powles N; Babbs C; Ficker M; Schimmang T; Maconochie M, Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization., Dev Biol 2004 Apr 1;268(1):24-38

J:128571, Selever J; Liu W; Lu MF; Behringer RR; Martin JF, Bmp4 in limb bud mesoderm regulates digit pattern by controlling AER development., Dev Biol 2004 Dec 15;276(2):268-79

J:92194, Li Y; Zhang H; Choi SC; Litingtung Y; Chiang C, Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis., Dev Biol 2004 Jun 1;270(1):214-31

J:92189, Lewis PM; Gritli-Linde A; Smeyne R; Kottmann A; McMahon AP, Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum., Dev Biol 2004 Jun 15;270(2):393-410

J:88802, Berman DM; Desai N; Wang X; Karhadkar SS; Reynon M; Abate-Shen C; Beachy PA; Shen MM, Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis., Dev Biol 2004 Mar 15;267(2):387-98

J:90053, Ohazama A; Hu Y; Schmidt-Ullrich R; Cao Y; Scheidereit C; Karin M; Sharpe PT, A dual role for Ikk alpha in tooth development., Dev Cell 2004 Feb;6(2):219-27

J:92212, Koziel L; Kunath M; Kelly OG; Vortkamp A, Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification., Dev Cell 2004 Jun;6(6):801-13

J:89029, Yashiro K; Zhao X; Uehara M; Yamashita K; Nishijima M; Nishino J; Saijoh Y; Sakai Y; Hamada H, Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb., Dev Cell 2004 Mar;6(3):411-22

J:89200, Jaskoll T; Leo T; Witcher D; Ormestad M; Astorga J; Bringas P Jr; Carlsson P; Melnick M, Sonic hedgehog signaling plays an essential role during embryonic salivary gland epithelial branching morphogenesis., Dev Dyn 2004 Apr;229(4):722-32

J:88955, Schwabe GC; Trepczik B; Suring K; Brieske N; Tucker AS; Sharpe PT; Minami Y; Mundlos S, Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome., Dev Dyn 2004 Feb;229(2):400-10

J:92067, Lei Q; Zelman AK; Kuang E; Li S; Matise MP, Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord., Development 2004 Aug;131(15):3593-604

J:92058, Tian H; Tenzen T; McMahon AP, Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse., Development 2004 Aug;131(16):4021-33

J:104488, Ozaki H; Nakamura K; Funahashi J; Ikeda K; Yamada G; Tokano H; Okamura HO; Kitamura K; Muto S; Kotaki H; Sudo K; Horai R; Iwakura Y; Kawakami K, Six1 controls patterning of the mouse otic vesicle., Development 2004 Feb;131(3):551-62

J:91052, Cobourne MT; Miletich I; Sharpe PT, Restriction of sonic hedgehog signalling during early tooth development., Development 2004 Jun;131(12):2875-85

J:88577, Mu X; Beremand PD; Zhao S; Pershad R; Sun H; Scarpa A; Liang S; Thomas TL; Klein WH, Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina., Development 2004 Mar;131(6):1197-210

J:88635, Long F; Chung UI; Ohba S; McMahon J; Kronenberg HM; McMahon AP, Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton., Development 2004 Mar;131(6):1309-18

J:89364, Bulgakov OV; Eggenschwiler JT; Hong DH; Anderson KV; Li T, FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues., Development 2004 May;131(9):2149-59

J:89474, Morikawa Y; Cserjesi P, Extra-embryonic vasculature development is regulated by the transcription factor HAND1., Development 2004 May;131(9):2195-204

J:128256, Mustonen T; Ilmonen M; Pummila M; Kangas AT; Laurikkala J; Jaatinen R; Pispa J; Gaide O; Schneider P; Thesleff I; Mikkola ML, Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages., Development 2004 Oct;131(20):4907-19

J:100340, Mori T; Yuxing Z; Takaki H; Takeuchi M; Iseki K; Hagino S; Kitanaka J; Takemura M; Misawa H; Ikawa M; Okabe M; Wanaka A, The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons., Eur J Neurosci 2004 Jun;19(12):3129-41

J:88344, Miao D; Liu H; Plut P; Niu M; Huo R; Goltzman D; Henderson JE, Impaired endochondral bone development and osteopenia in Gli2-deficient mice., Exp Cell Res 2004 Mar 10;294(1):210-22

J:89445, Jeong J; Mao J; Tenzen T; Kottmann AH; McMahon AP, Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia., Genes Dev 2004 Apr 15;18(8):937-51

J:89228, Chen MH; Li YJ; Kawakami T; Xu SM; Chuang PT, Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates., Genes Dev 2004 Mar 15;18(6):641-59

J:90567, Akiyama H; Lyons JP; Mori-Akiyama Y; Yang X; Zhang R; Zhang Z; Deng JM; Taketo MM; Nakamura T; Behringer RR; McCrea PD; de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation., Genes Dev 2004 May 1;18(9):1072-87

J:93364, Hahn H; Nitzki F; Schorban T; Hemmerlein B; Threadgill D; Rosemann M, Genetic mapping of a Ptch1-associated rhabdomyosarcoma susceptibility locus on mouse chromosome 2., Genomics 2004 Nov;84(5):853-8

J:111511, Tavella S; Biticchi R; Schito A; Minina E; Di Martino D; Pagano A; Vortkamp A; Horton WA; Cancedda R; Garofalo S, Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression., J Bone Miner Res 2004 Oct;19(10):1678-88

J:92499, Fu M; Lui VC; Sham MH; Pachnis V; Tam PK, Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut., J Cell Biol 2004 Aug 30;166(5):673-84

J:88817, Smits P; Dy P; Mitra S; Lefebvre V, Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate., J Cell Biol 2004 Mar 1;164(5):747-58

J:87618, Maes C; Stockmans I; Moermans K; Van Looveren R; Smets N; Carmeliet P; Bouillon R; Carmeliet G, Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival., J Clin Invest 2004 Jan;113(2):188-99

J:89218, Tang X; Kim AL; Feith DJ; Pegg AE; Russo J; Zhang H; Aszterbaum M; Kopelovich L; Epstein EH Jr; Bickers DR; Athar M, Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice., J Clin Invest 2004 Mar;113(6):867-75

J:87387, Moshiri A; Reh TA, Persistent progenitors at the retinal margin of ptc+/- mice., J Neurosci 2004 Jan 7;24(1):229-37

J:87798, Sagai T; Masuya H; Tamura M; Shimizu K; Yada Y; Wakana S; Gondo Y; Noda T; Shiroishi T, Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh)., Mamm Genome 2004 Jan;15(1):23-34

J:94710, Kappler R; Bauer R; Calzada-Wack J; Rosemann M; Hemmerlein B; Hahn H, Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma., Oncogene 2004 Nov 18;23(54):8785-95

J:94723, Inada M; Wang Y; Byrne MH; Rahman MU; Miyaura C; Lopez-Otin C; Krane SM, Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification., Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17192-7

J:82558, Ohuchi H; Tao H; Ohata K; Itoh N; Kato S; Noji S; Ono K, Fibroblast growth factor 10 is required for proper development of the mouse whiskers., Biochem Biophys Res Commun 2003 Mar 14;302(3):562-7

J:83607, Li L; Connelly MC; Wetmore C; Curran T; Morgan JI, Mouse embryos cloned from brain tumors., Cancer Res 2003 Jun 1;63(11):2733-6

J:86085, Lee Y; Miller HL; Jensen P; Hernan R; Connelly M; Wetmore C; Zindy F; Roussel MF; Curran T; Gilbertson RJ; McKinnon PJ, A molecular fingerprint for medulloblastoma., Cancer Res 2003 Sep 1;63(17):5428-37

J:86666, Michno K; Boras-Granic K; Mill P; Hui CC; Hamel PA, Shh expression is required for embryonic hair follicle but not mammary gland development., Dev Biol 2003 Dec 1;264(1):153-65

J:84056, Motoyama J; Milenkovic L; Iwama M; Shikata Y; Scott MP; Hui CC, Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification., Dev Biol 2003 Jul 1;259(1):150-61

J:83697, Weaver M; Batts L; Hogan BL, Tissue interactions pattern the mesenchyme of the embryonic mouse lung., Dev Biol 2003 Jun 1;258(1):169-84

J:82653, Oro AE; Higgins K, Hair cycle regulation of Hedgehog signal reception., Dev Biol 2003 Mar 15;255(2):238-48

J:86153, Kim JY; Nelson AL; Algon SA; Graves O; Sturla LM; Goumnerova LC; Rowitch DH; Segal RA; Pomeroy SL, Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice., Dev Biol 2003 Nov 1;263(1):50-66

J:86444, Ellis T; Smyth I; Riley E; Bowles J; Adolphe C; Rothnagel JA; Wicking C; Wainwright BJ, Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis., Dev Biol 2003 Nov 15;263(2):203-15

J:110732, Compagni A; Logan M; Klein R; Adams RH, Control of skeletal patterning by ephrinB1-EphB interactions., Dev Cell 2003 Aug;5(2):217-30

J:83305, Zhang Q; Murcia NS; Chittenden LR; Richards WG; Michaud EJ; Woychik RP; Yoder BK, Loss of the Tg737 protein results in skeletal patterning defects., Dev Dyn 2003 May;227(1):78-90

J:84605, Jeong Y; Epstein DJ, Distinct regulators of Shh transcription in the floor plate and notochord indicate separate origins for these tissues in the mouse node., Development 2003 Aug;130(16):3891-902

J:87042, Krebs O; Schreiner CM; Scott WJ Jr; Bell SM; Robbins DJ; Goetz JA; Alt H; Hawes N; Wolf E; Favor J, Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud., Development 2003 Dec;130(24):6037-47

J:80019, Kenney AM; Cole MD; Rowitch DH, Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors., Development 2003 Jan;130(1):15-28

J:83530, Dakubo GD; Wang YP; Mazerolle C; Campsall K; McMahon AP; Wallace VA, Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development., Development 2003 Jul;130(13):2967-80

J:81355, Yang Y; Topol L; Lee H; Wu J, Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation., Development 2003 Mar;130(5):1003-15

J:85472, Kawahira H; Ma NH; Tzanakakis ES; McMahon AP; Chuang PT; Hebrok M, Combined activities of hedgehog signaling inhibitors regulate pancreas development., Development 2003 Oct;130(20):4871-9

J:85949, Shikama N; Lutz W; Kretzschmar R; Sauter N; Roth JF; Marino S; Wittwer J; Scheidweiler A; Eckner R, Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation., EMBO J 2003 Oct 1;22(19):5175-85

J:86231, Kim JY; Mochizuki T; Akita K; Jung HS, Morphological evidence of the importance of epithelial tissue during mouse tongue development., Exp Cell Res 2003 Nov 1;290(2):217-26

J:81798, Chuang PT; Kawcak T; McMahon AP, Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung., Genes Dev 2003 Feb 1;17(3):342-7

J:81295, Mill P; Mo R; Fu H; Grachtchouk M; Kim PC; Dlugosz AA; Hui CC, Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development., Genes Dev 2003 Jan 15;17(2):282-94

J:82564, Brennan J; Tilmann C; Capel B, Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad., Genes Dev 2003 Mar 15;17(6):800-10

J:83385, Weston CR; Wong A; Hall JP; Goad ME; Flavell RA; Davis RJ, JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure., Genes Dev 2003 May 15;17(10):1271-80

J:85040, Ellis T; Smyth I; Riley E; Graham S; Elliot K; Narang M; Kay GF; Wicking C; Wainwright B, Patched 1 conditional null allele in mice., Genesis 2003 Jul;36(3):158-61

J:129156, Black GC; Mazerolle CJ; Wang Y; Campsall KD; Petrin D; Leonard BC; Damji KF; Evans DG; McLeod D; Wallace VA, Abnormalities of the vitreoretinal interface caused by dysregulated Hedgehog signaling during retinal development., Hum Mol Genet 2003 Dec 15;12(24):3269-76

J:85724, Bendall AJ; Hu G; Levi G; Abate-Shen C, Dlx5 regulates chondrocyte differentiation at multiple stages., Int J Dev Biol 2003 Jun;47(5):335-44

J:81440, Crick AP; Babbs C; Brown JM; Morriss-Kay GM, Developmental mechanisms underlying polydactyly in the mouse mutant Doublefoot., J Anat 2003 Jan;202(1):21-6

J:102978, Kimi K; Ohki K; Kumamoto H; Kondo M; Taniguchi Y; Tanigami A; Ooya K, Immunohistochemical and genetic analysis of mandibular cysts in heterozygous ptc knockout mice., J Oral Pathol Med 2003 Feb;32(2):108-13

J:84283, Kappler R; Calzada-Wack J; Schnitzbauer U; Koleva M; Herwig A; Piontek G; Graedler F; Adamski J; Heinzmann U; Schlegel J; Hemmerlein B; Quintanilla-Martinez L; Hahn H, Molecular characterization of Patched-associated rhabdomyosarcoma., J Pathol 2003 Jul;200(3):348-56

J:82151, Ioannides AS; Henderson DJ; Spitz L; Copp AJ, Role of Sonic hedgehog in the development of the trachea and oesophagus., J Pediatr Surg 2003 Jan;38(1):29-36

J:86406, Hashimoto-Torii K; Motoyama J; Hui CC; Kuroiwa A; Nakafuku M; Shimamura K, Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus., Mech Dev 2003 Oct;120(10):1097-111

J:84077, Khokha MK; Hsu D; Brunet LJ; Dionne MS; Harland RM, Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning., Nat Genet 2003 Jul;34(3):303-7

J:82377, Watkins DN; Berman DM; Burkholder SG; Wang B; Beachy PA; Baylin SB, Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer., Nature 2003 Mar 20;422(6929):313-7

J:86437, Huangfu D; Liu A; Rakeman AS; Murcia NS; Niswander L; Anderson KV, Hedgehog signalling in the mouse requires intraflagellar transport proteins., Nature 2003 Nov 6;426(6962):83-7

J:87181, Gold DA; Baek SH; Schork NJ; Rose DW; Larsen DD; Sachs BD; Rosenfeld MG; Hamilton BA, RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways., Neuron 2003 Dec 18;40(6):1119-31

J:85603, Machold R; Hayashi S; Rutlin M; Muzumdar MD; Nery S; Corbin JG; Gritli-Linde A; Dellovade T; Porter JA; Rubin LL; Dudek H; McMahon AP; Fishell G, Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches., Neuron 2003 Sep 11;39(6):937-50

J:86696, Zambrowicz BP; Abuin A; Ramirez-Solis R; Richter LJ; Piggott J; BeltrandelRio H; Buxton EC; Edwards J; Finch RA; Friddle CJ; Gupta A; Hansen G; Hu Y; Huang W; Jaing C; Key BW Jr; Kipp P; Kohlhauff B; Ma ZQ; Markesich D; Payne R; Potter DG; Qian N; Shaw J; Schrick J; Shi ZZ; Sparks MJ; Van Sligtenhorst I; Vogel P; Walke W; Xu N; Zhu Q; Person C; Sands AT, Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention., Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14109-14

J:76411, Lim L; Kalinichenko VV; Whitsett JA; Costa RH, Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele., Am J Physiol Lung Cell Mol Physiol 2002 May;282(5):L1012-22

J:77190, Calzada-Wack J; Kappler R; Schnitzbauer U; Richter T; Nathrath M; Rosemann M; Wagner SN; Hein R; Hahn H, Unbalanced overexpression of the mutant allele in murine Patched mutants., Carcinogenesis 2002 May;23(5):727-33

J:79457, Ma Y; Erkner A; Gong R; Yao S; Taipale J; Basler K; Beachy P, Hedgehog-Mediated Patterning of the Mammalian Embryo Requires Transporter-like Function of Dispatched., Cell 2002 Oct 4;111(1):63

J:79027, Caspary T; Garcia-Garcia MJ; Huangfu D; Eggenschwiler JT; Wyler MR; Rakeman AS; Alcorn HL; Anderson KV, Mouse dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling., Curr Biol 2002 Sep 17;12(18):1628-32

J:78407, O'Rourke MP; Soo K; Behringer RR; Hui CC; Tam PP, Twist plays an essential role in FGF and SHH signal transduction during mouse limb development., Dev Biol 2002 Aug 1;248(1):143-56

J:78384, Li C; Xiao J; Hormi K; Borok Z; Minoo P, Wnt5a participates in distal lung morphogenesis., Dev Biol 2002 Aug 1;248(1):68-81

J:77812, Perriton CL; Powles N; Chiang C; Maconochie MK; Cohn MJ, Sonic hedgehog signaling from the urethral epithelium controls external genital development., Dev Biol 2002 Jul 1;247(1):26-46

J:77801, Soo K; O'Rourke MP; Khoo PL; Steiner KA; Wong N; Behringer RR; Tam PP, Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo., Dev Biol 2002 Jul 15;247(2):251-70

J:79899, Grotewold L; Ruther U, The Fused toes (Ft) mouse mutation causes anteroposterior and dorsoventral polydactyly., Dev Biol 2002 Nov 1;251(1):129-41

J:78990, Lamm ML; Catbagan WS; Laciak RJ; Barnett DH; Hebner CM; Gaffield W; Walterhouse D; Iannaccone P; Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation., Dev Biol 2002 Sep 15;249(2):349-66

J:80081, Gritli-Linde A; Bei M; Maas R; Zhang XM; Linde A; McMahon AP, Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization., Development 2002 Dec;129(23):5323-37

J:79831, Kawakami T; Kawcak T; Li YJ; Zhang W; Hu Y; Chuang PT, Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling., Development 2002 Dec;129(24):5753-65

J:77683, Kobayashi T; Chung UI; Schipani E; Starbuck M; Karsenty G; Katagiri T; Goad DL; Lanske B; Kronenberg HM, PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps., Development 2002 Jun;129(12):2977-86

J:75946, Kanai-Azuma M; Kanai Y; Gad JM; Tajima Y; Taya C; Kurohmaru M; Sanai Y; Yonekawa H; Yazaki K; Tam PP; Hayashi Y, Depletion of definitive gut endoderm in Sox17-null mutant mice., Development 2002 May;129(10):2367-79

J:75942, Ybot-Gonzalez P; Cogram P; Gerrelli D; Copp AJ, Sonic hedgehog and the molecular regulation of mouse neural tube closure., Development 2002 May;129(10):2507-17

J:75943, Laurikkala J; Pispa J; Jung HS; Nieminen P; Mikkola M; Wang X; Saarialho-Kere U; Galceran J; Grosschedl R; Thesleff I, Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar., Development 2002 May;129(10):2541-53

J:79856, Rallu M; Machold R; Gaiano N; Corbin JG; McMahon AP; Fishell G, Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling., Development 2002 Nov;129(21):4963-74

J:79855, Anderson RM; Lawrence AR; Stottmann RW; Bachiller D; Klingensmith J, Chordin and noggin promote organizing centers of forebrain development in the mouse., Development 2002 Nov;129(21):4975-87

J:79482, Liu Y; Liu C; Yamada Y; Fan CM, growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb., Development 2002 Nov;129(22):5289-300

J:79481, Yu J; Carroll TJ; McMahon AP, Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney., Development 2002 Nov;129(22):5301-12

J:79392, Bai CB; Auerbach W; Lee JS; Stephen D; Joyner AL, Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway., Development 2002 Oct;129(20):4753-61

J:79394, Ishibashi M; McMahon AP, A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo., Development 2002 Oct;129(20):4807-19

J:78219, Aubin J; Dery U; Lemieux M; Chailler P; Jeannotte L, Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling., Development 2002 Sep;129(17):4075-87

J:75879, Liu Z; Xu J; Colvin JS; Ornitz DM, Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18., Genes Dev 2002 Apr 1;16(7):859-69

J:79879, Akiyama H; Chaboissier MC; Martin JF; Schedl A; De Crombrugghe B, The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6., Genes Dev 2002 Nov 1;16(21):2813-28

J:80206, Wijgerde M; McMahon JA; Rule M; McMahon AP, A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord., Genes Dev 2002 Nov 15;16(22):2849-64

J:79100, Riccomagno MM; Martinu L; Mulheisen M; Wu DK; Epstein DJ, Specification of the mammalian cochlea is dependent on Sonic hedgehog., Genes Dev 2002 Sep 15;16(18):2365-78

J:82019, Marshall KE; Godden EL; Yang F; Burgers S; Buck KJ; Sikela JM, In silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases., Genome Biol 2002;3(12):RESEARCH0078

J:74618, Deussing J; Kouadio M; Rehman S; Werber I; Schwinde A; Peters C, Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13., Genomics 2002 Feb;79(2):225-40

J:83507, Stoeger T; Proetzel GE; Welzel H; Papadimitriou A; Dony C; Balling R; Hofmann C, In situ gene expression analysis during BMP2-induced ectopic bone formation in mice shows simultaneous endochondral and intramembranous ossification., Growth Factors 2002 Dec;20(4):197-210

J:104869, Blanc I; Bach A; Robert B, Unusual pattern of Sonic hedgehog expression in the polydactylous mouse mutant Hemimelic extra-toes., Int J Dev Biol 2002;46(7):969-74

J:81331, Yada Y; Makino S; Chigusa-Ishiwa S; Shiroishi T, The mouse polydactylous mutation, luxate (lx), causes anterior shift of the anteroposterior border in the developing hindlimb bud., Int J Dev Biol 2002;46(7):975-82

J:76559, Ernest S; Christensen B; Gilfix BM; Mamer OA; Hosack A; Rodier M; Colmenares C; McGrath J; Bale A; Balling R; Sankoff D; Rosenblatt DS; Nadeau JH, Genetic and molecular control of folate-homocysteine metabolism in mutant mice., Mamm Genome 2002 May;13(5):259-67

J:76826, Zuniga A; Quillet R; Perrin-Schmitt F; Zeller R, Mouse Twist is required for fibroblast growth factor-mediated epithelial-mesenchymal signalling and cell survival during limb morphogenesis., Mech Dev 2002 Jun;114(1-2):51

J:75699, Albrecht AN; Schwabe GC; Stricker S; Boddrich A; Wanker EE; Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements., Mech Dev 2002 Mar;112(1-2):53-67

J:79512, Tribioli C; Robledo R; Lufkin T, The murine fork head gene Foxn2 is expressed in craniofacial, limb, CNS and somitic tissues during embryogenesis., Mech Dev 2002 Oct;118(1-2):161

J:78708, Wang YP; Dakubo G; Howley P; Campsall KD; Mazarolle CJ; Shiga SA; Lewis PM; McMahon AP; Wallace VA, Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells., Nat Neurosci 2002 Sep;5(9):831-2

J:78402, Sun X; Mariani FV; Martin GR, Functions of FGF signalling from the apical ectodermal ridge in limb development., Nature 2002 Aug 1;418(6897):501-8

J:78941, Litingtung Y; Dahn RD; Li Y; Fallon JF; Chiang C, Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity., Nature 2002 Aug 29;418(6901):979-83

J:80000, The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs, Nature 2002;420():563-573

J:75757, Fults D; Pedone C; Dai C; Holland EC, MYC expression promotes the proliferation of neural progenitor cells in culture and in vivo., Neoplasia 2002 Jan-Feb;4(1):32-9

J:79667, Weiss WA; Israel M; Cobbs C; Holland E; James CD; Louis DN; Marks C; McClatchey AI; Roberts T; Van Dyke T; Wetmore C; Chiu IM; Giovannini M; Guha A; Higgins RJ; Marino S; Radovanovic I; Reilly K; Aldape K, Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum., Oncogene 2002 Oct 24;21(49):7453-63

J:79666, Pazzaglia S; Mancuso M; Atkinson MJ; Tanori M; Rebessi S; Majo VD; Covelli V; Hahn H; Saran A, High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice., Oncogene 2002 Oct 24;21(49):7580-4

J:79798, Berman DM; Karhadkar SS; Hallahan AR; Pritchard JI; Eberhart CG; Watkins DN; Chen JK; Cooper MK; Taipale J; Olson JM; Beachy PA, Medulloblastoma growth inhibition by hedgehog pathway blockade., Science 2002 Aug 30;297(5586):1559-61

J:116953, Yamago G; Takata Y; Furuta I; Urase K; Momoi T; Huh N, Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice., Arch Dermatol Res 2001 Sep;293(9):435-41

J:108687, Pierucci-Alves F; Clark AM; Russell LD, A developmental study of the Desert hedgehog-null mouse testis., Biol Reprod 2001 Nov;65(5):1392-402

J:67452, Wetmore C; Eberhart DE; Curran T, Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched., Cancer Res 2001 Jan 15;61(2):513-6

J:69771, Lewis PM; Dunn MP; McMahon JA; Logan M; Martin JF; St-Jacques B; McMahon AP, Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1., Cell 2001 Jun 1;105(5):599-612

J:70021, Zhang XM; Ramalho-Santos M; McMahon AP, Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node., Cell 2001 Jun 15;105(6):781-92

J:69463, Huelsken J; Vogel R; Erdmann B; Cotsarelis G; Birchmeier W, beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin., Cell 2001 May 18;105(4):533-45

J:70735, Lee CS; May NR; Fan CM, Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant., Dev Biol 2001 Aug 1;236(1):17-29

J:71184, Gritli-Linde A; Lewis P; McMahon AP; Linde A, The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides., Dev Biol 2001 Aug 15;236(2):364-86

J:71186, Chiang C; Litingtung Y; Harris MP; Simandl BK; Li Y; Beachy PA; Fallon JF, Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function., Dev Biol 2001 Aug 15;236(2):421-35

J:72380, Makino S; Masuya H; Ishijima J; Yada Y; Shiroishi T, A Spontaneous Mouse Mutation, mesenchymal dysplasia (mes), Is Caused by a Deletion of the Most C-Terminal Cytoplasmic Domain of patched (ptc)., Dev Biol 2001 Nov 1;239(1):95-106

J:80666, Smits P; Li P; Mandel J; Zhang Z; Deng JM; Behringer RR; de Croumbrugghe B; Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation., Dev Cell 2001 Aug;1(2):277-90

J:73071, Long F; Zhang XM; Karp S; Yang Y; McMahon AP, Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation., Development 2001 Dec;128(24):5099-108

J:73075, Dahmane N; Sanchez P; Gitton Y; Palma V; Sun T; Beyna M; Weiner H; Ruiz i Altaba A, The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis., Development 2001 Dec;128(24):5201-12

J:66789, Treier M; O'Connell S; Gleiberman A; Price J; Szeto DP; Burgess R; Chuang PT; McMahon AP; Rosenfeld MG, Hedgehog signaling is required for pituitary gland development., Development 2001 Feb;128(3):377-86

J:67153, Long F; Schipani E; Asahara H; Kronenberg H; Montminy M, The CREB family of activators is required for endochondral bone development., Development 2001 Feb;128(4):541-50

J:69847, Mahlapuu M; Enerback S; Carlsson P, Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations., Development 2001 Jun;128(12):2397-406

J:68722, Dyer MA; Farrington SM; Mohn D; Munday JR; Baron MH, Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo., Development 2001 May;128(10):1717-30

J:72303, Haraguchi R; Mo R; Hui C; Motoyama J; Makino S; Shiroishi T; Gaffield W; Yamada G, Unique functions of Sonic hedgehog signaling during external genitalia development., Development 2001 Nov;128(21):4241-50

J:71880, Beverdam A; Brouwer A; Reijnen M; Korving J; Meijlink F, Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice., Development 2001 Oct;128(20):3975-86

J:108799, Soegiarto DW; Kiachopoulos S; Schipani E; Juppner H; Erben RG; Lanske B, Partial rescue of PTH/PTHrP receptor knockout mice by targeted expression of the Jansen transgene., Endocrinology 2001 Dec;142(12):5303-10

J:72500, Izraeli S; Lowe LA; Bertness VL; Campaner S; Hahn H; Kirsch IR; Kuehn MR, Genetic evidence that Sil is required for the sonic hedgehog response pathway., Genesis 2001 Oct;31(2):72-7

J:71525, Hayes C; Morriss-Kay GM, Retinoic acid specifically downregulates Fgf4 and inhibits posterior cell proliferation in the developing mouse autopod., J Anat 2001 May;198(Pt 5):561-8

J:74145, Gori F; Schipani E; Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development., J Cell Biochem 2001 Apr 2-27;82(1):46-57

J:67277, Chung UI; Schipani E; McMahon AP; Kronenberg HM, Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development., J Clin Invest 2001 Feb;107(3):295-304

J:73000, Corcoran RB; Scott MP, A mouse model for medulloblastoma and basal cell nevus syndrome., J Neurooncol 2001 Jul;53(3):307-18

J:69826, Juriloff DM; Harris MJ; Brown CJ, Unravelling the complex genetics of cleft lip in the mouse model., Mamm Genome 2001 Jun;12(6):426-35

J:67306, Koebernick K; Hollemann T; Pieler T, Molecular cloning and expression analysis of the Hedgehog receptors XPtc1 and XSmo in Xenopus laevis., Mech Dev 2001 Feb;100(2):303-8

J:66531, Kraus P; Fraidenraich D; Loomis CA, Some distal limb structures develop in mice lacking Sonic hedgehog signaling., Mech Dev 2001 Jan;100(1):45-58

J:66532, Hecksher-Sorensen J; Sharpe J, 3D confocal reconstruction of gene expression in mouse., Mech Dev 2001 Jan;100(1):59-63

J:65060, Kawai J; Shinagawa A; Shibata K; Yoshino M; Itoh M; Ishii Y; Arakawa T; Hara A; Fukunishi Y; Konno H; Adachi J; Fukuda S; Aizawa K; Izawa M; Nishi K; Kiyosawa H; Kondo S; Yamanaka I; Saito T; Okazaki Y; Gojobori T; Bono H; Kasukawa T; Saito R; Kadota K; Matsuda HA; Ashburner M; Batalov S; Casavant T; Fleischmann W; Gaasterland T; Gissi C; King B; Kochiwa H; Kuehl P; Lewis S; Matsuo Y; Nikaido I; Pesole G; Quackenbush J; Schriml LM; Staubli F; Suzuki R; Tomita M; Wagner L; Washio T; Sakai K; Okido T; et al, Functional annotation of a full-length mouse cDNA collection., Nature 2001 Feb 8;409(6821):685-90

J:74191, Urase K; Soyama A; Fujita E; Momoi T, Expression of RA175 mRNA, a new member of the immunoglobulin superfamily, in developing mouse brain., Neuroreport 2001 Oct 29;12(15):3217-21

J:71832, Lee CS; Buttitta L; Fan CM, Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite., Proc Natl Acad Sci U S A 2001 Sep 25;98(20):11347-52

J:72283, Hebert JL; Khugyani F; Athar M; Kopelovich L; Epstein EH Jr; Aszterbaum M, Chemoprevention of Basal Cell Carcinomas in the ptc1(+/-) Mouse - Green and Black Tea., Skin Pharmacol Appl Skin Physiol 2001 Nov-Dec;14(6):358-62

J:71964, Juriloff DM; Gunn TM; Harris MJ; Mah DG; Wu MK; Dewell SL, Multifactorial genetics of exencephaly in SELH/Bc mice., Teratology 2001 Oct;64(4):189-200

J:65900, Clark AM; Garland KK; Russell LD, Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type leydig cells and normal development of peritubular cells and seminiferous tubules, Biol Reprod 2000 Dec;63(6):1825-38

J:61727, Wetmore C; Eberhart DE; Curran T, The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched, Cancer Res 2000 Apr 15;60(8):2239-46

J:61723, Zhang Z; Yu X; Zhang Y; Geronimo B; Lovlie A; Fromm SH; Chen Y, Targeted misexpression of constitutively active BMP receptor-IB causes bifurcation, duplication, and posterior transformation of digit in mouse limb., Dev Biol 2000 Apr 15;220(2):154-67

J:64018, Wang CC; Biben C; Robb L; Nassir F; Barnett L; Davidson NO; Koentgen F; Tarlinton D; Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera., Dev Biol 2000 Aug 15;224(2):152-67

J:62158, Ramalho-Santos M; Melton DA; McMahon AP, Hedgehog signals regulate multiple aspects of gastrointestinal development., Development 2000 Jun;127(12):2763-72

J:65294, Dassule HR; Lewis P; Bei M; Maas R; McMahon AP, Sonic hedgehog regulates growth and morphogenesis of the tooth, Development 2000 Nov;127(22):4775-85

J:65293, Hebrok M; Kim SK; St Jacques B; McMahon AP; Melton DA, Regulation of pancreas development by hedgehog signaling., Development 2000 Nov;127(22):4905-13

J:61188, Zurawel RH; Allen C; Wechsler-Reya R; Scott MP; Raffel C, Evidence that haploinsufficiency of Ptch leads to medulloblastoma in mice., Genes Chromosomes Cancer 2000 May;28(1):77-81

J:63198, Iwata T; Chen L; Li Cl; Ovchinnikov DA; Behringer RR; Francomano CA; Deng CX, A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos, Hum Mol Genet 2000 Jul 1;9(11):1603-13

J:64180, Outram SV; Varas A; Pepicelli CV; Crompton T, Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte., Immunity 2000 Aug;13(2):187-97

J:64528, Hahn H; Wojnowski L; Specht K; Kappler R; Calzada-Wack J; Potter D; Zimmer A; Muller U; Samson E; Quintanilla-Martinez L, Patched target igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma, J Biol Chem 2000 Sep 15;275(37):28341-4

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J:61509, Satokata I; Ma L; Ohshima H; Bei M; Woo I; Nishizawa K; Maeda T; Takano Y; Uchiyama M; Heaney S; Peters H; Tang Z; Maxson R; Maas R, Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation., Nat Genet 2000 Apr;24(4):391-5

J:61488, Pennisi D; Gardner J; Chambers D; Hosking B; Peters J; Muscat G; Abbott C; Koopman P, Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice., Nat Genet 2000 Apr;24(4):434-7

J:62547, Barna M; Hawe N; Niswander L; Pandolfi PP, Plzf regulates limb and axial skeletal patterning., Nat Genet 2000 Jun;25(2):166-72

J:60109, Hardcastle Z; Hui CC; Sharpe PT, The Shh signalling pathway in early tooth development., Cell Mol Biol (Noisy-le-grand) 1999 Jul;45(5):567-78

J:54463, Wallace VA, Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum., Curr Biol 1999 Apr 22;9(8):445-8

J:52207, Chiang C; Swan RZ; Grachtchouk M; Bolinger M; Litingtung Y; Robertson EK; Cooper MK; Gaffield W; Westphal H; Beachy PA; Dlugosz AA, Essential role for Sonic hedgehog during hair follicle morphogenesis., Dev Biol 1999 Jan 1;205(1):1-9

J:52212, Lu MF; Cheng HT; Lacy AR; Kern MJ; Argao EA; Potter SS; Olson EN; Martin JF, Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis., Dev Biol 1999 Jan 1;205(1):145-57

J:56424, Goodrich LV; Jung D; Higgins KM; Scott MP, Overexpression of ptc1 inhibits induction of Shh target genes and prevents normal patterning in the neural tube., Dev Biol 1999 Jul 15;211(2):323-34

J:54600, Zhang Y; Zhao X; Hu Y; St. Amand T; Zhang M; Ramamurthy R; Qiu M; Chen Y, Msx1 is required for the induction of Patched by Sonic hedgehog in the mammalian tooth germ., Dev Dyn 1999 May;215(1):45-53

J:53903, Theil T; Alvarez-Bolado G; Walter A; Ruther U, Gli3 is required for Emx gene expression during dorsal telencephalon development., Development 1999 Aug;126(16):3561-71

J:51596, Lu MF; Cheng HT; Kern MJ; Potter SS; Tran B; Diekwisch TG; Martin JF, prx-1 functions cooperatively with another paired-related homeobox gene, prx-2, to maintain cell fates within the craniofacial mesenchyme., Development 1999 Feb;126(3):495-504

J:49322, Zuniga A; Zeller R, Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity., Development 1999 Jan;126(1):13-21

J:51128, Qu S; Tucker SC; Zhao Q; deCrombrugghe B; Wisdom R, Physical and genetic interactions between Alx4 and Cart1., Development 1999 Jan;126(2):359-69

J:54773, Wallace VA; Raff MC, A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve., Development 1999 Jul;126(13):2901-9

J:54912, Karlsson L; Bondjers C; Betsholtz C, Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle., Development 1999 Jun;126(12):2611-21

J:42408, Lewis MT; Ross S; Strickland PA; Sugnet CW; Jimenez E; Scott MP; Daniel CW, Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1., Development 1999 Nov;126(22):5181-93

J:56195, Milenkovic L; Goodrich LV; Higgins KM; Scott MP, Mouse patched1 controls body size determination and limb patterning., Development 1999 Oct;126(20):4431-40

J:54263, Walterhouse DO; Yoon JW; Iannaccone PM, Developmental pathways: Sonic hedgehog-Patched-GLI., Environ Health Perspect 1999 Mar;107(3):167-71

J:58089, Tisljar K; Deussing J; Peters C, Cathepsin J, a novel murine cysteine protease of the papain family with a placenta-restricted expression., FEBS Lett 1999 Oct 15;459(3):299-304

J:57297, St-Jacques B; Hammerschmidt M; McMahon AP, Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation [published erratum appears in Genes Dev 1999 Oct 1;13(19):2617], Genes Dev 1999 Aug 15;13(16):2072-86

J:58105, Woldeyesus MT; Britsch S; Riethmacher D; Xu L; Sonnenberg-Riethmacher E; Abou-Rebyeh F; Harvey R; Caroni P; Birchmeier C, Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development., Genes Dev 1999 Oct 1;13(19):2538-48

J:53317, Hall JM; Hooper JE; Finger TE, Expression of sonic hedgehog, patched, and Gli1 in developing taste papillae of the mouse., J Comp Neurol 1999 Apr 5;406(2):143-55

J:59453, Hahn H; Wojnowski L; Miller G; Zimmer A, The patched signaling pathway in tumorigenesis and development: lessons from animal models., J Mol Med 1999 Jun;77(6):459-68

J:57948, Rowitch DH; S.-Jacques B; Lee SM; Flax JD; Snyder EY; McMahon AP, Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells., J Neurosci 1999 Oct 15;19(20):8954-65

J:58674, Bell SM; Schreiner CM; Scott WJ, Disrupting the establishment of polarizing activity by teratogen exposure., Mech Dev 1999 Nov;88(2):147-57

J:58328, Aszterbaum M; Epstein J; Oro A; Douglas V; LeBoit PE; Scott MP; Epstein EH Jr, Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice., Nat Med 1999 Nov;5(11):1285-91

J:53760, Chuang PT; McMahon AP, Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein., Nature 1999 Feb 18;397(6720):617-21

J:55887, Izraeli S; Lowe LA; Bertness VL; Good DJ; Dorward DW; Kirsch IR; Kuehn MR, The SIL gene is required for mouse embryonic axial development and left-right specification., Nature 1999 Jun 17;399(6737):691-4

J:57341, Parmantier E; Lynn B; Lawson D; Turmaine M; Namini SS; Chakrabarti L; McMahon AP; Jessen KR; Mirsky R, Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths [see comments], Neuron 1999 Aug;23(4):713-24

J:52548, Wechsler-Reya RJ; Scott MP, Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog [see comments], Neuron 1999 Jan;22(1):103-14

J:59339, Wicking C; Smyth I; Bale A, The hedgehog signalling pathway in tumorigenesis and development., Oncogene 1999 Dec 20;18(55):7844-51

J:58240, Merlino G; Helman LJ, Rhabdomyosarcoma--working out the pathways., Oncogene 1999 Sep 20;18(38):5340-8

J:113791, Fuse N; Maiti T; Wang B; Porter JA; Hall TM; Leahy DJ; Beachy PA, Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched., Proc Natl Acad Sci U S A 1999 Sep 28;96(20):10992-9

J:52397, Koebbe MJ; Golden JA; Bennett G; Finnell RH; Mackler SA, Effects of prenatal cocaine exposure on embryonic expression of sonic hedgehog., Teratology 1999 Jan;59(1):12-9

J:50050, St-Jacques B; Dassule HR; Karavanova I; Botchkarev VA; Li J; Danielian PS; McMahon JA; Lewis PM; Paus R; McMahon AP, Sonic hedgehog signaling is essential for hair development., Curr Biol 1998 Sep 24;8(19):1058-68

J:50051, Pepicelli CV; Lewis PM; McMahon AP, Sonic hedgehog regulates branching morphogenesis in the mammalian lung., Curr Biol 1998 Sep 24;8(19):1083-6

J:50462, Dassule HR; McMahon AP, Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth., Dev Biol 1998 Oct 15;202(2):215-27

J:47321, Kim HJ; Rice DP; Kettunen PJ; Thesleff I, FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development., Development 1998 Apr;125(7):1241-51

J:49251, Matise MP; Epstein DJ; Park HL; Platt KA; Joyner AL, Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system., Development 1998 Aug;125(15):2759-70

J:49252, Hardcastle Z; Mo R; Hui CC; Sharpe PT, The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants., Development 1998 Aug;125(15):2803-11

J:49653, Yang Y; Guillot P; Boyd Y; Lyon MF; McMahon AP, Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling., Development 1998 Aug;125(16):3123-32

J:50292, Naski MC; Colvin JS; Coffin JD; Ornitz DM, Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3., Development 1998 Dec;125(24):4977-88

J:46225, Hayes C; Brown JM; Lyon MF; Morriss-Kay GM, Sonic hedgehog is not required for polarising activity in the Doublefoot mutant mouse limb bud., Development 1998 Feb;125(3):351-7

J:49164, Ding Q; Motoyama J; Gasca S; Mo R; Sasaki H; Rossant J; Hui CC, Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice., Development 1998 Jul;125(14):2533-43

J:49902, Liu A; Joyner AL; Turnbull DH, Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells., Mech Dev 1998 Jul;75(1-2):107-15

J:51701, Motoyama J; Heng H; Crackower MA; Takabatake T; Takeshima K; Tsui LC ; Hui C, Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis., Mech Dev 1998 Nov;78(1-2):81-4

J:45907, Motoyama J; Takabatake T; Takeshima K; Hui C, Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog [letter], Nat Genet 1998 Feb;18(2):104-6

J:49603, Motoyama J; Liu J; Mo R; Ding Q; Post M; Hui CC, Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus [see comments], Nat Genet 1998 Sep;20(1):54-7

J:49604, Litingtung Y; Lei L; Westphal H; Chiang C, Sonic hedgehog is essential to foregut development [see comments], Nat Genet 1998 Sep;20(1):58-61

J:47421, Hahn H; Wojnowski L; Zimmer AM; Hall J; Miller G; Zimmer A, Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome [see comments], Nat Med 1998 May;4(5):619-22

J:49400, Yueh YG; Gardner DP; Kappen C, Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8., Proc Natl Acad Sci U S A 1998 Aug 18;95(17):9956-61

J:50930, Carpenter D; Stone DM; Brush J; Ryan A; Armanini M; Frantz G ; Rosenthal A ; de Sauvage FJ, Characterization of two patched receptors for the vertebrate hedgehog protein family., Proc Natl Acad Sci U S A 1998 Nov 10;95(23):13630-4

J:50593, Chung UI; Lanske B; Lee K; Li E; Kronenberg H, The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation., Proc Natl Acad Sci U S A 1998 Oct 27;95(22):13030-5

J:46793, Johnson RL; Scott MP, Control of cell growth and fate by patched genes., Cold Spring Harb Symp Quant Biol 1997;62():205-15

J:44143, Apelqvist A; Ahlgren U; Edlund H, Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas., Curr Biol 1997 Oct 1;7(10):801-4

J:42454, Grindley JC; Bellusci S; Perkins D; Hogan BL, Evidence for the involvement of the Gli gene family in embryonic mouse lung development., Dev Biol 1997 Aug 15;188(2):337-48

J:44838, Thomas BL; Tucker AS; Qui M; Ferguson CA; Hardcastle Z; Rubenstein JL; Sharpe PT, Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition., Development 1997 Dec;124(23):4811-8

J:38383, Bellusci S; Furuta Y; Rush MG; Henderson R; Winnier G; Hogan BL, Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis., Development 1997 Jan;124(1):53-63

J:38389, Jensen AM; Wallace VA, Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina., Development 1997 Jan;124(2):363-71

J:41710, Takabatake T; Ogawa M; Takahashi TC; Mizuno M; Okamoto M; Takeshima K, Hedgehog and patched gene expression in adult ocular tissues., FEBS Lett 1997 Jun 30;410(2-3):485-9

J:41401, Grindley JC; Hargett LK; Hill RE; Ross A; Hogan BL, Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon., Mech Dev 1997 Jun;64(1-2):111-26

J:39659, Platt KA; Michaud J; Joyner AL, Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice., Mech Dev 1997 Mar;62(2):121-35

J:39658, Buscher D; Bosse B; Heymer J; Ruther U, Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development., Mech Dev 1997 Mar;62(2):175-82

J:41861, Hynes M; Stone DM; Dowd M; Pitts-Meek S; Goddard A; Gurney A ; Rosenthal A, Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1., Neuron 1997 Jul;19(1):15-26

J:42441, Goodrich LV; Milenkovic L; Higgins KM; Scott MP, Altered neural cell fates and medulloblastoma in mouse patched mutants., Science 1997 Aug 22;277(5329):1109-13

J:40166, Oro AE; Higgins KM; Hu Z; Bonifas JM; Epstein EH Jr; Scott MP, Basal cell carcinomas in mice overexpressing sonic hedgehog., Science 1997 May 2;276(5313):817-21

J:47524, Hahn H; Wicking C; Zaphiropoulous PG; Gailani MR; Shanley S; Chidambaram A; Vorechovsky I; Holmberg E; Unden AB; Gillies S; Negus K; Smyth I; Pressman C; Leffell DJ; Gerrard B; Goldstein AM; Dean M; Toftgard R; Chenevix-Trench G; Wainwright B; Bale AE, Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome., Cell 1996 Jun 14;85(6):841-51

J:35809, Epstein DJ; Marti E; Scott MP; McMahon AP, Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway., Development 1996 Sep;122(9):2885-94

J:31336, Goodrich LV; Johnson RL; Milenkovic L; McMahon JA; Scott MP, Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog., Genes Dev 1996 Feb 1;10(3):301-12

J:33153, Hahn H; Christiansen J; Wicking C; Zaphiropoulos PG; Chidambaram A; Gerrard B; Vorechovsky I; Bale AE; Toftgard R; Dean M; Wainwright B, A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities., J Biol Chem 1996 May 24;271(21):12125-8

J:32739, Sweet HO; Bronson RT; Donahue LR; Davisson MT, Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse., J Hered 1996 Mar-Apr;87(2):87-95

J:36573, Stone DM; Hynes M; Armanini M; Swanson TA; Gu Q; Johnson RL; Scott MP; Pennica D; Goddard A; Phillips H; Noll M; Hooper JE; de Sauvage F; Rosenthal A, The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog [see comments], Nature 1996 Nov 14;384(6605):129-34

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