J:154656, Follit JA; Xu F; Keady BT; Pazour GJ, Characterization of mouse IFT complex B., Cell Motil Cytoskeleton 2009 Aug;66(8):457-68
J:154376, Stottmann RW; Tran PV; Turbe-Doan A; Beier DR, Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain., Dev Biol 2009 Nov 1;335(1):166-78
J:142685, Yu J; Carroll TJ; Rajagopal J; Kobayashi A; Ren Q; McMahon AP, A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney., Development 2009 Jan;136(1):161-71
J:146634, Ohazama A ; Haycraft CJ ; Seppala M ; Blackburn J ; Ghafoor S ; Cobourne M ; Martinelli DC ; Fan CM ; Peterkova R ; Lesot H ; Yoder BK ; Sharpe PT, Primary cilia regulate Shh activity in the control of molar tooth number., Development 2009 Mar;136(6):897-903
J:147574, Norman RX; Ko HW; Huang V; Eun CM; Abler LL; Zhang Z; Sun X; Eggenschwiler JT, Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling., Hum Mol Genet 2009 May 15;18(10):1740-54
J:153142, Clement CA; Kristensen SG; Mollgard K; Pazour GJ; Yoder BK; Larsen LA; Christensen ST, The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation., J Cell Sci 2009 Sep 1;122(Pt 17):3070-82
J:150229, Lehman JM; Laag E; Michaud EJ; Yoder BK, An essential role for dermal primary cilia in hair follicle morphogenesis., J Invest Dermatol 2009 Feb;129(2):438-48
J:153498, In progress, MGI Direct Data Submission 2009;():
J:154128, Wong SY; Seol AD; So PL; Ermilov AN; Bichakjian CK; Epstein EH Jr; Dlugosz AA; Reiter JF, Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis., Nat Med 2009 Sep;15(9):1055-61
J:154130, Han YG; Kim HJ; Dlugosz AA; Ellison DW; Gilbertson RJ; Alvarez-Buylla A, Dual and opposing roles of primary cilia in medulloblastoma development., Nat Med 2009 Sep;15(9):1062-5
J:148449, Nauli SM; Kawanabe Y; Kaminski JJ; Pearce WJ; Ingber DE; Zhou J, Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1., Circulation 2008 Mar 4;117(9):1161-71
J:138713, Cho A; Ko HW; Eggenschwiler JT, FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism., Dev Biol 2008 Sep 1;321(1):27-39
J:138088, Lehman JM; Michaud EJ; Schoeb TR; Aydin-Son Y; Miller M; Yoder BK, The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men., Dev Dyn 2008 Aug;237(8):1960-71
J:138332, Johnson ET; Nicola T; Roarty K; Yoder BK; Haycraft CJ; Serra R, Role for primary cilia in the regulation of mouse ovarian function., Dev Dyn 2008 Aug;237(8):2053-60
J:132152, Chamberlain CE; Jeong J; Guo C; Allen BL; McMahon AP, Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning., Development 2008 Mar;135(6):1097-106
J:139508, Gao J; DeRouen MC; Chen CH; Nguyen M; Nguyen NT; Ido H; Harada K; Sekiguchi K; Morgan BA; Miner JH; Oro AE; Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis., Genes Dev 2008 Aug 1;22(15):2111-24
J:142500, Willaredt MA; Hasenpusch-Theil K; Gardner HA; Kitanovic I; Hirschfeld-Warneken VC; Gojak CP; Gorgas K; Bradford CL; Spatz J; Wolfl S; Theil T; Tucker KL, A crucial role for primary cilia in cortical morphogenesis., J Neurosci 2008 Nov 26;28(48):12887-900
J:132369, Corbit KC; Shyer AE; Dowdle WE; Gaulden J; Singla V; Reiter JF, Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms., Nat Cell Biol 2008 Jan;10(1):70-6
J:133725, Tran PV; Haycraft CJ; Besschetnova TY; Turbe-Doan A; Stottmann RW; Herron BJ; Chesebro AL; Qiu H; Scherz PJ; Shah JV; Yoder BK; Beier DR, THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia., Nat Genet 2008 Apr;40(4):403-10
J:131308, Jones C; Roper VC; Foucher I; Qian D; Banizs B; Petit C; Yoder BK; Chen P, Ciliary proteins link basal body polarization to planar cell polarity regulation., Nat Genet 2008 Jan;40(1):69-77
J:135664, Han YG; Spassky N; Romaguera-Ros M; Garcia-Verdugo JM; Aguilar A; Schneider-Maunoury S; Alvarez-Buylla A, Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells., Nat Neurosci 2008 Mar;11(3):277-84
J:142875, Follit JA; San Agustin JT; Xu F; Jonassen JA; Samtani R; Lo CW; Pazour GJ, The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex., PLoS Genet 2008 Dec;4(12):e1000315
J:125882, Banizs B; Komlosi P; Bevensee MO; Schwiebert EM; Bell PD; Yoder BK, Altered pH(i) regulation and Na(+)/HCO3(-) transporter activity in choroid plexus of cilia-defective Tg737(orpk) mutant mouse., Am J Physiol Cell Physiol 2007 Apr;292(4):C1409-16
J:121342, Song B; Haycraft CJ; Seo HS; Yoder BK; Serra R, Development of the post-natal growth plate requires intraflagellar transport proteins., Dev Biol 2007 May 1;305(1):202-16
J:124940, Nechiporuk T; Fernandez TE; Vasioukhin V, Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in dlg5(-/-) mice., Dev Cell 2007 Sep;13(3):338-50
J:117033, Haycraft CJ; Zhang Q; Song B; Jackson WS; Detloff PJ; Serra R; Yoder BK, Intraflagellar transport is essential for endochondral bone formation., Development 2007 Jan;134(2):307-16
J:145113, Chizhikov VV; Davenport J; Zhang Q; Shih EK; Cabello OA; Fuchs JL; Yoder BK; Millen KJ, Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool., J Neurosci 2007 Sep 5;27(36):9780-9
J:122045, McGlashan SR; Haycraft CJ; Jensen CG; Yoder BK; Poole CA, Articular cartilage and growth plate defects are associated with chondrocyte cytoskeletal abnormalities in Tg737orpk mice lacking the primary cilia protein polaris., Matrix Biol 2007 May;26(4):234-46
J:119488, Hossain Z; Ali SM; Ko HL; Xu J; Ng CP; Guo K; Qi Z; Ponniah S; Hong W; Hunziker W, Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1., Proc Natl Acad Sci U S A 2007 Jan 30;104(5):1631-6
J:125042, Pierreux CE; Poll AV; Kemp CR; Clotman F; Maestro MA; Cordi S; Ferrer J; Leyns L; Rousseau GG; Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse., Gastroenterology 2006 Feb;130(2):532-41
J:111714, Lang B; Song B; Davidson W; MacKenzie A; Smith N; McCaig CD; Harmar AJ; Shen S, Expression of the human PAC1 receptor leads to dose-dependent hydrocephalus-related abnormalities in mice., J Clin Invest 2006 Jul;116(7):1924-34
J:108293, Shillingford JM; Murcia NS; Larson CH; Low SH; Hedgepeth R; Brown N; Flask CA; Novick AC; Goldfarb DA; Kramer-Zucker A; Walz G; Piontek KB; Germino GG; Weimbs T, The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease., Proc Natl Acad Sci U S A 2006 Apr 4;103(14):5466-71
J:105241, Sawamoto K; Wichterle H; Gonzalez-Perez O; Cholfin JA; Yamada M; Spassky N; Murcia NS; Garcia-Verdugo JM; Marin O; Rubenstein JL; Tessier-Lavigne M; Okano H; Alvarez-Buylla A, New neurons follow the flow of cerebrospinal fluid in the adult brain., Science 2006 Feb 3;311(5761):629-32
J:101454, Liu W; Murcia NS; Duan Y; Weinbaum S; Yoder BK; Schwiebert E; Satlin LM, Mechanoregulation of intracellular Ca2+ concentration is attenuated in collecting duct of monocilium-impaired orpk mice., Am J Physiol Renal Physiol 2005 Nov;289(5):F978-88
J:102215, Schneider L; Clement CA; Teilmann SC; Pazour GJ; Hoffmann EK; Satir P; Christensen ST, PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts., Curr Biol 2005 Oct 25;15(20):1861-6
J:119858, Banizs B; Pike MM; Millican CL; Ferguson WB; Komlosi P; Sheetz J; Bell PD; Schwiebert EM; Yoder BK, Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus., Development 2005 Dec;132(23):5329-39
J:98800, Liu A; Wang B; Niswander LA, Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors., Development 2005 Jul;132(13):3103-11
J:95813, Zhang Q; Davenport JR; Croyle MJ; Haycraft CJ; Yoder BK, Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice., Lab Invest 2005 Jan;85(1):45-64
J:115756, Haycraft CJ; Banizs B; Aydin-Son Y; Zhang Q; Michaud EJ; Yoder BK, Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function., PLoS Genet 2005 Oct;1(4):e53
J:98216, Garcia-Garcia MJ; Eggenschwiler JT; Caspary T; Alcorn HL; Wyler MR; Huangfu D; Rakeman AS; Lee JD; Feinberg EH; Timmer JR; Anderson KV, Inaugural Article: Analysis of mouse embryonic patterning and morphogenesis by forward genetics., Proc Natl Acad Sci U S A 2005 Apr 26;102(17):5913-9
J:99680, The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome, Science 2005;309(5740):1559-1563
J:90990, Cano DA; Murcia NS; Pazour GJ; Hebrok M, Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization., Development 2004 Jul;131(14):3457-67
J:89880, Bonnafe E; Touka M; AitLounis A; Baas D; Barras E; Ucla C; Moreau A; Flamant F; Dubruille R; Couble P; Collignon J; Durand B; Reith W, The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification., Mol Cell Biol 2004 May;24(10):4417-27
J:87130, Guay-Woodford LM, Murine models of polycystic kidney disease: molecular and therapeutic insights., Am J Physiol Renal Physiol 2003 Dec;285(6):F1034-49
J:83305, Zhang Q; Murcia NS; Chittenden LR; Richards WG; Michaud EJ; Woychik RP; Yoder BK, Loss of the Tg737 protein results in skeletal patterning defects., Dev Dyn 2003 May;227(1):78-90
J:104022, Brown NE; Murcia NS, Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice., Kidney Int 2003 Apr;63(4):1220-9
J:86437, Huangfu D; Liu A; Rakeman AS; Murcia NS; Niswander L; Anderson KV, Hedgehog signalling in the mouse requires intraflagellar transport proteins., Nature 2003 Nov 6;426(6962):83-7
J:86696, Zambrowicz BP; Abuin A; Ramirez-Solis R; Richter LJ; Piggott J; BeltrandelRio H; Buxton EC; Edwards J; Finch RA; Friddle CJ; Gupta A; Hansen G; Hu Y; Huang W; Jaing C; Key BW Jr; Kipp P; Kohlhauff B; Ma ZQ; Markesich D; Payne R; Potter DG; Qian N; Shaw J; Schrick J; Shi ZZ; Sparks MJ; Van Sligtenhorst I; Vogel P; Walke W; Xu N; Zhu Q; Person C; Sands AT, Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention., Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14109-14
J:83908, Yoder BK; Tousson A; Millican L; Wu JH; Bugg CE Jr; Schafer JA; Balkovetz DF, Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium., Am J Physiol Renal Physiol 2002 Mar;282(3):F541-52
J:77403, Pazour GJ; San Agustin JT; Follit JA; Rosenbaum JL; Witman GB, Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease., Curr Biol 2002 Jun 4;12(11):R378-80
J:103374, Yoder BK; Hou X; Guay-Woodford LM, The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia., J Am Soc Nephrol 2002 Oct;13(10):2508-16
J:74701, Hou X; Mrug M; Yoder BK; Lefkowitz EJ; Kremmidiotis G; D'Eustachio P; Beier DR; Guay-Woodford LM, Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease., J Clin Invest 2002 Feb;109(4):533-40
J:68697, Haycraft CJ; Swoboda P; Taulman PD; Thomas JH; Yoder BK, The C. elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms., Development 2001 May;128(9):1493-505
J:83906, Taulman PD; Haycraft CJ; Balkovetz DF; Yoder BK, Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia., Mol Biol Cell 2001 Mar;12(3):589-99
J:74115, Nakanishi K; Sweeney WE Jr; Avner ED; Murcia NS, Expression of the orpk disease gene during kidney development and maturation., Pediatr Nephrol 2001 Mar;16(3):219-26
J:73583, Sommardahl C; Cottrell M; Wilkinson JE; Woychik RP; Johnson DK, Phenotypic variations of orpk mutation and chromosomal localization of modifiers influencing kidney phenotype., Physiol Genomics 2001 Dec 21;7(2):127-34
J:62025, Murcia NS; Richards WG; Yoder BK; Mucenski ML; Dunlap JR; Woychik RP, The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination., Development 2000 Jun;127(11):2347-55
J:65500, Pazour GJ; Dickert BL; Vucica Y; Seeley ES; Rosenbaum JL; Witman GB; Cole DG, Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella, J Cell Biol 2000 Oct 30;151(3):709-18
J:57294, Colvin JS; Feldman B; Nadeau JH; Goldfarb M; Ornitz DM, Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene., Dev Dyn 1999 Sep;216(1):72-88
J:46764, Richards WG; Sweeney WE; Yoder BK; Wilkinson JE; Woychik RP; Avner ED, Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease., J Clin Invest 1998 Mar 1;101(5):935-9
J:40810, Yoder BK; Richards WG; Sommardahl C; Sweeney WE; Michaud EJ; Wilkinson JE ; Avner ED ; Woychik RP, Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion., Am J Pathol 1997 Jun;150(6):2231-41
J:47067, Sommardahl CS; Woychik RP; Sweeney WE; Avner ED; Wilkinson JE, Efficacy of taxol in the orpk mouse model of polycystic kidney disease., Pediatr Nephrol 1997 Dec;11(6):728-33
J:37149, Richards WG; Yoder BK; Isfort RJ; Detilleux PG; Foster C; Neilsen N ; Woychik RP ; Wilkinson JE, Oval cell proliferation associated with the murine insertional mutation TgN737Rpw., Am J Pathol 1996 Dec;149(6):1919-30
J:33899, Yoder BK; Richards WG; Sweeney WE; Wilkinson JE; Avener ED; Woychik RP, Insertional mutagenesis and molecular analysis of a new gene associated with polycystic kidney disease., Proc Assoc Am Physicians 1995 Oct;107(3):314-23
J:18508, Moyer JH; Lee-Tischler MJ; Kwon HY; Schrick JJ; Avner ED; Sweeney WE; Godfrey VL; Cacheiro NL; Wilkinson JE; Woychik RP, Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice., Science 1994 May 27;264(5163):1329-33
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