References
Query Results -- Details
MGI Accession ID: MGI:3039308
J Number: J:89268
Other Accession IDs:
Title: Cerebral ischemia in 5-lipoxygenase knockout mice.
Authors: Kitagawa K; Matsumoto M; Hori M
Journal: Brain Res
Volume: 1004
Issue: 1-2
Date: 2004 Apr 9
Year: 2004
Pages: 198-202
Review Status: Peer Reviewed
Abstract:
Cerebral ischemia induces 5-lipoxygenase translocation and leukotriene production in the brain. We tried to clarify the pathological significance of 5-lipoxygenase on cerebral ischemia using 5-lipoxygenase knockout mice. No significant difference was observed in the infarct size following permanent and transient ischemia for 60 min between both types of mice. The present study did not support the idea that leukotriene production is involved in infarct expansion in focal cerebral ischemia.
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