References
Query Results -- Details
MGI Accession ID: MGI:3028821
J Number: J:88012
Other Accession IDs:
Title: Modifier genes and protective alleles in humans and mice.
Authors: Nadeau JH
Journal: Curr Opin Genet Dev
Volume: 13
Issue: 3
Date: 2003 Jun
Year: 2003
Pages: 290-5
Review Status: Peer Reviewed
Abstract:
Interest in modifier genes is growing rapidly because of their ability to modulate the phenotype of individuals with monogenic and multigenic traits and diseases. A neglected class of modifiers is protective alleles that can suppress disease in otherwise susceptible individuals. Together these modifier genes and protective alleles provide important glimpses into the molecular and cellular basis for the functional networks that provide robustness and homeostasis in complex biological systems.
Additional Information:
