References
Query Results -- Details
MGI Accession ID: MGI:2135358
J Number: J:69716
Other Accession IDs:
Title: Combined histiologic and molecular features reveal previously unappreciated subsets of lymphoma in AKXD recombinant inbred mice.
Authors: Morse HC; Qi C; Chattopadhyay SK; Hori M; Taddesse-Heath L; Ozato K; Hartley JW; Taylor BA; Ward JM; Jenkins NA; Copeland NG; Fredrickson TN
Journal: Leuk Res
Volume: 25
Issue: 8
Date: 2001 Aug
Year: 2001
Pages: 719-33
Review Status: Peer Reviewed
Abstract:
Hematopoietic neoplasms developing in AKXD recombinant inbred, NFS.V(+) and ICSBP knockout mice were assessed using morphologic, cytologic and molecular criteria that relate these disorders to human lymphoma and leukemia. Lymphoma types included precursor T-cell and B-cell lymphoblastic, small lymphocytic, splenic marginal zone, follicular, and diffuse large cell (DLCL). In addition to previously defined subtypes of DLCL composed of centroblasts or immunoblasts, two additional subtypes are defined here: lymphoblastic lymphoma like (LL) and lymphoma characterized by a histiocytic reaction (HS). DLCL(HS) were distinguished from true histiocytic lymphomas by the presence of clonal Ig gene rearrangements.
