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Query Results -- Details

MGI Accession ID: MGI:55086
J Number: J:6611
Other Accession IDs: Title: Tyrosinase subcellular distribution and kinetic parameters in wild type and C-locus mutant C57BL/6J mice.
Authors: Townsend D; Witkop CJ Jr; Mattson J
Journal: J Exp Zool
Volume: 216
Issue: 1
Date: 1981 Apr
Year: 1981
Pages: 113-9
Review Status: Peer Reviewed

Abstract:

The distribution and kinetic parameters of tyrosinase (EC 1.14.-18.1) from anagen hair follicles of the C57BL/6J mouse and several c-locus mutants were investigated. The results showed that c-locus mutations not only influenced the total tyrosinase activity, but the subcellular distribution as well. The kinetic parameters of tyrosinase were not influenced by the pigment mutations, suggesting that the mutations were not influencing the structure of the enzyme.

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