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Query Results -- Details

MGI Accession ID: MGI:55062
J Number: J:6587
Other Accession IDs: Title: Dilute (d) coat colour mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome.
Authors: Jenkins NA; Copeland NG; Taylor BA; Lee BK
Journal: Nature
Volume: 293
Issue: 5831
Date: 1981 Oct 1
Year: 1981
Pages: 370-4
Review Status: Peer Reviewed

Abstract:

The single endogenous DBA/2J ectropic provirus segregated concordantly with the dilute (d) coat colour mutation on chromosome 9 in 53/53 DBA/2J-derived recombinant inbred mouse strains and all seven inbred and mutant strains tested that carry the d allele. Analysis of DNA from a spontaneous DBA/2J d revertant (d+2J) showed that these mice lack ecotropic-specific MuLV DNA sequences and suggested that the dilute mutation resulted from integration of an ecotropic provirus into the mouse genome.

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