References
Query Results -- Details
MGI Accession ID: MGI:1888622
J Number: J:64036
Other Accession IDs:
Title: Role of inducible nitric oxide synthase in resistance to Mycobacterium leprae in mice.
Authors: Adams LB; Job CK; Krahenbuhl JL
Journal: Infect Immun
Volume: 68
Issue: 9
Date: 2000 Sep
Year: 2000
Pages: 5462-5
Review Status: Peer Reviewed
Abstract:
The manifestation of leprosy in humans is largely determined by host immunity to Mycobacterium leprae and is a model for immunoregulation in a human disease. However, animal models available for exploration of the leprosy spectrum are inadequate. This study explored M. leprae infection in mice deficient in inducible nitric oxide synthase, and this report describes elements resembling borderline tuberculoid leprosy in humans.
Additional Information:
