References
Query Results -- Details
MGI Accession ID: MGI:54956
J Number: J:6480
Other Accession IDs:
Title: Gene for neuraminidase activity on mouse chromosome 17 near h-2: pleiotropic effects on multiple hydrolases.
Authors: Womack JE; Yan DL; Potier M
Journal: Science
Volume: 212
Issue: 4490
Date: 1981 Apr 3
Year: 1981
Pages: 63-5
Review Status: Peer Reviewed
Abstract:
The low activity of liver neuraminidase that is characteristic of mouse strain SM/J is inherited as a single gene on chromosome 17, near the major histocompatibility complex. This gene, neuraminidase-1 (Neu-1), is represented by the low activity allele Neu-1s in SM/J and the high activity allele Neu-1b in C57BL/6J and most other strains. Previously described variations in the posttranslational processing of acid phosphatase, alpha-mannosidase, arylsulfatase-B, and alpha-glucosidase are attributed to pleiotropic effects of this gene.
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