References
Query Results -- Details
MGI Accession ID: MGI:1333348
J Number: J:53730
Other Accession IDs:
Title: Advantages of the CBA mouse in leukemogenesis research.
Authors: Rithidech KN; Cronkite EP; Bond VP
Journal: Blood Cells Mol Dis
Volume: 25
Issue: 1
Date: 1999 Feb
Year: 1999
Pages: 38-45
Review Status: Peer Reviewed
Abstract:
The objectives of this review are to: (a) demonstrate that the male CBA/Ca mouse has several characteristics that make it an excellent animal for the study of leukemogenesis, (b) show that several of the genetic abnormalities observed in the male CBA/Ca mouse during the development of radiation induced acute myeloid leukemia (AML) are syntenic with those frequently detected in patients with myeloid disorders such as myelodysplastic syndrome and AML, (c) illustrate that leukemia-related chromosomal lesions are the indicators for high risk individuals.
