References
Query Results -- Details
MGI Accession ID: MGI:49014
J Number: J:477
Other Accession IDs:
Title: cDNA cloning and structure of mouse putative Ah receptor.
Authors: Ema M; Sogawa K; Watanabe N; Chujoh Y; Matsushita N; Gotoh O; Funae Y; Fujii-Kuriyama Y
Journal: Biochem Biophys Res Commun
Volume: 184
Issue: 1
Date: 1992 Apr 15
Year: 1992
Pages: 246-53
Review Status: Peer Reviewed
Abstract:
Mouse cDNA clones for a putative Ah receptor have been isolated from a cDNA library of mRNA from Hepa-1 cells by an oligonucleotide probe produced by PCR with a pair of primers which was synthesized according to the reported N-terminal sequence of 26 amino acids. The cDNA clones encode a polypeptide of 805 amino acids with a helix-loop-helix motif and with some similarity to a certain region designated PAS of Drosophila Per and Sim, and human Arnt protein. Cotransfection of an expression vector of the Ah receptor with a reporter plasmid pMC6.3k consisting of CYP1A1 promoter and CAT structural gene into CV-1 cells enhanced the CAT expression in response to added 3-methylcholanthrene.
Additional Information:
