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MGI Accession ID: MGI:73767
J Number: J:26136
Other Accession IDs: Title: Polymorphism for PCR-analyzed microsatellites between the inbred mouse strains LG and SM.
Authors: Routman EJ; Cheverud JM
Journal: Mamm Genome
Volume: 6
Issue: 6
Date: 1995 Jun
Year: 1995
Pages: 401-4
Review Status: Peer Reviewed

Abstract:

Using agarose gel electrophoresis, we surveyed four strains of inbred mice (AKR/J, C57BL/J, LG/J, and SM/J) for 472 microsatellite loci. Agarose electrophoresis proved to be extremely efficient in separating alleles differing by six or more base pairs and detected a majority of allelic differences of between two and six base pairs. Overall, 64.4% of loci showed polymorphism among the four strains, and pairwise comparisons ranged from 42.1% to 48.1%. Microsatellite polymorphism for strains LG/J and SM/J has not been previously described and was sufficiently high (47.1%) to make these size-divergent strains excellent candidates for quantitative trait loci (QTL) analysis of normal growth.

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