References
Query Results -- Details
MGI Accession ID: MGI:67773
J Number: J:19624
Other Accession IDs:
Title: Structure and expression of the hairless gene of mice.
Authors: Cachon-Gonzalez MB; Fenner S; Coffin JM; Moran C; Best S; Stoye JP
Journal: Proc Natl Acad Sci U S A
Volume: 91
Issue: 16
Date: 1994 Aug 2
Year: 1994
Pages: 7717-21
Review Status: Peer Reviewed
Abstract:
The hairless mutation of mice was caused by insertion of a murine leukemia virus. Starting with sequences flanking the provirus, a series of overlapping clones surrounding the viral integration site were obtained. By using a combination of sequencing, PCR, and exon-trapping techniques, the hairless gene was identified. It encodes a predicted protein of 1182 amino acids, including a potential zinc-finger domain. The expression patterns of the gene closely reflect the phenotype of animals carrying the hairless mutation.
Additional Information:
