References
Query Results -- Details
MGI Accession ID: MGI:3619793
J Number: J:106939
Other Accession IDs:
Title: Genomic and proteomic analysis of mammary tumors arising in transgenic mice.
Authors: Xie L; Xu BJ; Gorska AE; Shyr Y; Schwartz SA; Cheng N; Levy S; Bierie B; Caprioli RM; Moses HL
Journal: J Proteome Res
Volume: 4
Issue: 6
Date: 2005 Nov-Dec
Year: 2005
Pages: 2088-98
Review Status: Peer Reviewed
Abstract:
Transforming growth factor-beta (TGF-beta) is the prototype of a large family of signaling molecules. TGF-beta signaling profoundly influences tumor development as demonstrated in several engineered mouse models. The present study was designed to identify differences by cDNA microarray and MALDI-TOF MS analyses in mammary carcinomas with and without TGF-beta signaling. The results demonstrate a significant potential for combination of profiling technologies to further understand the molecular mechanisms of breast cancer.
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