References
Query Results -- Details
MGI Accession ID: MGI:3610791
J Number: J:103844
Other Accession IDs:
Title: Deficits in sexual and aggressive behaviors in Cnga2 mutant mice.
Authors: Mandiyan VS; Coats JK; Shah NM
Journal: Nat Neurosci
Volume: 8
Issue: 12
Date: 2005 Dec
Year: 2005
Pages: 1660-2
Review Status: Peer Reviewed
Abstract:
Odors detected by the vomeronasal organ or the main olfactory epithelium (MOE) trigger social behaviors in many animals. It is unknown whether MOE neurons detect cues that initiate mating or aggression. We demonstrate that mice lacking functional CNGA2 (cyclic nucleotide-gated channel alpha2), which is required for odor-evoked MOE signaling, fail to mate or fight, suggesting a broad and essential role for the MOE in regulating these behaviors.
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